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Hepatitis C virus mutation affects proteasomal epitope processing
Seifert, Ulrike, Liermann, Heike, Racanelli, Vito, Halenius, Anne, Wiese, Manfred, Wedemeyer, Heiner, ...
The high incidence of hepatitis C virus (HCV) persistence raises the question of how HCV interferes with host immune responses. Studying a single-source HCV outbreak, we identified an HCV mutation...
Hepatitis C virus mutation affects proteasomal epitope processing
Seifert, Ulrike, Liermann, Heike, Racanelli, Vito, Halenius, Anne, Wiese, Manfred, Wedemeyer, Heiner, ...
The high incidence of hepatitis C virus (HCV) persistence raises the question of how HCV interferes with host immune responses. Studying a single-source HCV outbreak, we identified an HCV mutation...
Escape from HLA-B*08-Restricted CD8 T Cells by Hepatitis C Virus Is Associated with Fitness Costs ▿
Salloum, Shadi, Oniangue-Ndza, Cesar, Neumann-Haefelin, Christoph, Hudson, Laura, Giugliano, Silvia, Aus Dem Siepen, Marc, ...
The inherent sequence diversity of the hepatitis C virus (HCV) represents a major hurdle for the adaptive immune system to control viral replication. Mutational escape within targeted CD8 epitopes...