Manoj T. Duraisingh

Publication List Details

Period

2009 - 2009

Number

14

Co-Authors

Sir2 Paralogues Cooperate to Regulate Virulence Genes and Antigenic Variation in Plasmodium falciparum (2009)

Christopher J. Tonkin, Céline K. Carret, Manoj T. Duraisingh, Till S. Voss, Stuart A. Ralph, Mirja Hommel, ...

Cytoadherance of Plasmodium falciparum-infected erythrocytes in the brain, organs and peripheral microvasculature is linked to morbidity and mortality associated with severe malaria. Parasite-derived...

Identification and Disruption of the Gene Encoding the Third Member of the Low-Molecular-Mass Rhoptry Complex in Plasmodium falciparum

Baldi, Deborah L., Good, Robert, Duraisingh, Manoj T., Crabb, Brendan S., Cowman, Alan F.

The low-molecular-mass rhoptry complex of Plasmodium falciparum consists of three proteins, rhoptry-associated protein 1 (RAP1), RAP2, and RAP3. The genes encoding RAP1 and RAP2 are known; however,...

Phenotypic variation of Plasmodium falciparum merozoite proteins directs receptor targeting for invasion of human erythrocytes

Duraisingh, Manoj T., Triglia, Tony, Ralph, Stuart A., Rayner, Julian C., Barnwell, John W., McFadden, Geoffrey I., ...

The members of the phylum Apicomplexa parasitize a wide range of eukaryotic host cells. Plasmodium falciparum, responsible for the most virulent form of malaria, invades human erythrocytes using...

Erythrocyte-binding antigen 175 mediates invasion in Plasmodium falciparum utilizing sialic acid-dependent and -independent pathways

Duraisingh, Manoj T., Maier, Alexander G., Triglia, Tony, Cowman, Alan F.

The Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175) is a ligand for merozoite invasion into human erythrocytes that binds to glycophorin A in a sialic acid-dependent manner. P....

Identification and Disruption of the Gene Encoding the Third Member of the Low-Molecular-Mass Rhoptry Complex in Plasmodium falciparum

Baldi, Deborah L., Good, Robert, Duraisingh, Manoj T., Crabb, Brendan S., Cowman, Alan F.

The low-molecular-mass rhoptry complex of Plasmodium falciparum consists of three proteins, rhoptry-associated protein 1 (RAP1), RAP2, and RAP3. The genes encoding RAP1 and RAP2 are known; however,...

Phenotypic variation of Plasmodium falciparum merozoite proteins directs receptor targeting for invasion of human erythrocytes

Duraisingh, Manoj T., Triglia, Tony, Ralph, Stuart A., Rayner, Julian C., Barnwell, John W., McFadden, Geoffrey I., ...

The members of the phylum Apicomplexa parasitize a wide range of eukaryotic host cells. Plasmodium falciparum, responsible for the most virulent form of malaria, invades human erythrocytes using...

Erythrocyte-binding antigen 175 mediates invasion in Plasmodium falciparum utilizing sialic acid-dependent and -independent pathways

Duraisingh, Manoj T., Maier, Alexander G., Triglia, Tony, Cowman, Alan F.

The Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175) is a ligand for merozoite invasion into human erythrocytes that binds to glycophorin A in a sialic acid-dependent manner. P....

Molecular Analysis of Erythrocyte Invasion in Plasmodium falciparum Isolates from Senegal▿ ‡

Jennings, Cameron V., Ahouidi, Ambroise D., Zilversmit, Martine, Bei, Amy K., Rayner, Julian, Sarr, Ousmane, ...

The human malaria parasite, Plasmodium falciparum, utilizes multiple ligand-receptor interactions for the invasion of human erythrocytes. Members of the reticulocyte binding protein homolog (PfRh)...

Evidence-Based Annotation of the Malaria Parasite's Genome Using Comparative Expression Profiling

Zhou, Yingyao, Ramachandran, Vandana, Kumar, Kota Arun, Westenberger, Scott, Refour, Phillippe, Zhou, Bin, ...

A fundamental problem in systems biology and whole genome sequence analysis is how to infer functions for the many uncharacterized proteins that are identified, whether they are conserved across...

Plasmodium falciparum Sir2: an Unusual Sirtuin with Dual Histone Deacetylase and ADP-Ribosyltransferase Activity▿ †

Merrick, Catherine J., Duraisingh, Manoj T.

In the human malaria parasite Plasmodium falciparum, a member of the sirtuin family has been implicated in the epigenetic regulation of virulence genes that are vital to malaria pathogenesis and...

Sir2 Paralogues Cooperate to Regulate Virulence Genes and Antigenic Variation in Plasmodium falciparum

Tonkin, Christopher J, Carret, Céline K, Duraisingh, Manoj T, Voss, Till S, Ralph, Stuart A, Hommel, Mirja, ...

Cytoadherance of Plasmodium falciparum-infected erythrocytes in the brain, organs and peripheral microvasculature is linked to morbidity and mortality associated with severe malaria. Parasite-derived...