Closing gaps in the human genome using sequencing by synthesis (2009)
Garber, Manuel, Zody, Michael C, Arachchi, Harindra M, Berlin, Aaron, Gnerre, Sante, Green, Lisa M, ...
Abstract The most recent release of the finished human genome contains 260 euchromatic gaps (excluding chromosome Y). Recent work has helped explain a large number of these unresolved regions as...
Closing gaps in the human genome using sequencing by synthesis (2009)
Arachchi, Harindra M., Green, Lisa M., Zody, Michael C., Lennon, Niall, Gnerre, Sante, Berlin, Aaron, ...
The most recent release of the finished human genome contains 260 euchromatic gaps (excluding chromosome Y). Recent work has helped explain a large number of these unresolved regions as 'structural'...
Identifying novel constrained elements by exploiting biased substitution patterns (2009)
Garber, Manuel, Guttman, Mitchell, Clamp, Michele, Zody, Michael C., Friedman, Nir, Xie, Xiaohui
Motivation: Comparing the genomes from closely related species provides a powerful tool to identify functional elements in a reference genome. Many methods have been developed to identify conserved...
Quality scores and SNP detection in sequencing-by-synthesis systems (2008)
Brockman, William, Alvarez, Pablo, Young, Sarah, Garber, Manuel, Giannoukos, Georgia, Lee, William L., ...
Promising new sequencing technologies, based on sequencing-by-synthesis (SBS), are starting to deliver large amounts of DNA sequence at very low cost. Polymorphism detection is a key application. We...
On quadratic vector fields preserving a family of quadrics /--by Manuel Garber. (1999)
"UMI:9931713."
Quality scores and SNP detection in sequencing-by-synthesis systems
Brockman, William, Alvarez, Pablo, Young, Sarah, Garber, Manuel, Giannoukos, Georgia, Lee, William L., ...
Promising new sequencing technologies, based on sequencing-by-synthesis (SBS), are starting to deliver large amounts of DNA sequence at very low cost. Polymorphism detection is a key application. We...
Identifying novel constrained elements by exploiting biased substitution patterns
Garber, Manuel, Guttman, Mitchell, Clamp, Michele, Zody, Michael C., Friedman, Nir, Xie, Xiaohui
Motivation: Comparing the genomes from closely related species provides a powerful tool to identify functional elements in a reference genome. Many methods have been developed to identify conserved...
Khalil, Ahmad M., Guttman, Mitchell, Huarte, Maite, Garber, Manuel, Raj, Arjun, Rivea Morales, Dianali, ...
We recently showed that the mammalian genome encodes >1,000 large intergenic noncoding (linc)RNAs that are clearly conserved across mammals and, thus, functional. Gene expression patterns have...
Closing gaps in the human genome using sequencing by synthesis
Garber, Manuel, Zody, Michael C, Arachchi, Harindra M, Berlin, Aaron, Gnerre, Sante, Green, Lisa M, ...
A novel method for closing non-structural gaps in the human genome assembly using 454 sequencing is presented here.