Manuel Mattheisen

Common variants conferring risk of schizophrenia (2009)

Stefansson, Hreinn, Ophoff, Roel A, Steinberg, Stacy, Andreassen, Ole A, Cichon, Sven, Rujescu, Dan, ...

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The DISC locus and schizophrenia: evidence from an association study in a central European sample and from a meta-analysis across different European populations (2009)

Schumacher, Johannes, Laje, Gonzalo, Jamra, Rami Abou, Becker, Tim, Mühleisen, Thomas W., Vasilescu, Catalina, ...

Association studies, as well as the initial translocation family study, identified the gene Disrupted-In-Schizophrenia-1 (DISC1) as a risk factor for schizophrenia. DISC1 encodes a multifunctional...

Brain-specific tryptophan hydroxylase 2 (TPH2): a functional Pro206Ser substitution and variation in the 5'-region are associated with bipolar affective disorder (2008)

Cichon, Sven, Winge, Ingeborg, Mattheisen, Manuel, Georgi, Alexander, Karpushova, Anna, Freudenberg, Jan, ...

The neurotransmitter serotonin [5-hydroxytryptamine (5-HT)] controls a broad range of biological functions that are disturbed in affective disorder. In the brain, 5-HT production is controlled by...

Linkage analysis using sex-specific recombination fractions with GENEHUNTER-MODSCORE (2007)

Dietter, Johannes, Mattheisen, Manuel, Fürst, Robert, Rüschendorf, Franz, Wienker, Thomas F., Strauch, Konstantin

Motivation: Sex-specific marker maps have become increasingly available. We have implemented the usage of sex-specific recombination frequencies in the GENEHUNTER-MODSCORE program that performs...

Linkage analysis using sex-specific recombination fractions with GENEHUNTER-MODSCORE (2006)

Johannes Dietter, Manuel Mattheisen, Robert Fürst, Franz Rüschendorf, Thomas F. Wienker, Konstantin Strauch

Motivation: Sex-specific marker maps have become increasingly available. We have implemented the usage of sex-specific recombi-nation frequencies in the GENEHUNTER-MODSCORE program that performs...