Both SEPT2and MLLare down-regulated in MLL-SEPT2therapy-related myeloid neoplasia (2009)
Cerveira, Nuno, Santos, Joana, Bizarro, Susana, Costa, Vera, Ribeiro, Franclim R, Lisboa, Susana, ...
Abstract Background A relevant role of septins in leukemogenesis has been uncovered by their involvement as fusion partners in MLL -related leukemia. Recently, we have established the MLL-SEPT2 gene...
A universal assay for detection of oncogenic fusion transcripts by oligo microarray analysis (2009)
Skotheim, Rolf I, Thomassen, Gard OS, Eken, Marthe, Lind, Guro E, Micci, Francesca, Ribeiro, Franclim R, ...
Abstract Background The ability to detect neoplasia-specific fusion genes is important not only in cancer research, but also increasingly in clinical settings to ensure that correct diagnosis is made...
A universal assay for detection of oncogenic fusion transcripts by oligo microarray analysis. (2009)
Skotheim, Rolf I, Thomassen, Gard O S, Eken, Marthe, Lind, Guro E, Micci, Francesca, Ribeiro, Franclim R, ...
BACKGROUND: The ability to detect neoplasia-specific fusion genes is important not only in cancer research, but also increasingly in clinical settings to ensure that correct diagnosis is made and the...
Costa, Vera L, Henrique, Rui, Ribeiro, Franclim R, Pinto, Mafalda, Oliveira, Jorge, Lobo, Francisco, ...
Abstract Background Aberrant promoter hypermethylation of cancer-associated genes occurs frequently during carcinogenesis and may serve as a cancer biomarker. In this study we aimed at defining a...
Ribeiro, Franclim R, Henrique, Rui, Hektoen, Merete, Berg, Marianne, Jerónimo, Carmen, Teixeira, Manuel R, ...
Abstract Background In order to gain new insights into the molecular mechanisms involved in prostate cancer, we performed array-based comparative genomic hybridization (aCGH) on a series of 46...
Mesquita, Bárbara, Veiga, Isabel, Pereira, Deolinda, Tavares, Ana, Pinto, Isabel M, Pinto, Carla, ...
Abstract Background The mechanisms of chemoresistance in ovarian cancer patients remain largely to be elucidated. Paclitaxel/cisplatin combination is the standard chemotherapeutic treatment for this...
Lind, Guro E, Skotheim, Rolf I, Fraga, Mario F, Abeler, Vera M, Henrique, Rui, Saatcioglu, Fahri, ...
Abstract Background Recent studies have demonstrated that the NKX3.1 protein is commonly down-regulated in testicular germ cell tumors (TGCTs) and prostate carcinomas. The homeobox gene NKX3.1 maps...
Molecular cytogenetic characterization of proximal-type epithelioid sarcoma (2004)
Modena, Piergiorgio, Pedeutour, Florence, Teixeira, Manuel R, Facchinetti, Federica, ...
Proximal-type epithelioid sarcoma is a recently described soft-tissue tumor that is distinguished from conventional-type epithelioid sarcoma by a far more aggressive clinical course, frequent...
Diep, Chieu B, Teixeira, Manuel R, Thorstensen, Lin, Wiig, Johan N, Eknæs, Mette, Nesland, Jahn M, ...
Abstract Background Colorectal cancer (CRC) is one of the most common causes of cancer-related deaths in the Western world, and despite the fact that metastases are usually the ultimate cause of...
Oliveira, Carla, Westra, Jantine L, Arango, Diego, Ollikainen, Miina, Domingo, Enric, Ferreira, Ana, ...
In sporadic colorectal tumours the BRAFV600E is associated with microsatellite instability (MSI-H) and inversely associated to KRAS mutations. Tumours from HNPCC patients carrying germline mutations...
Oliveira, Carla, Westra, Jantine L., Arango, Diego, Ollikainen, Miina, Domingo, Enric, Ferreira, Ana, ...
In sporadic colorectal tumours the BRAFV600E is associated with microsatellite instability (MSI-H) and inversely associated to KRAS mutations. Tumours from hereditary non-polyposis colorectal cancer...
Oliveira, Carla, Westra, Jantine L, Arango, Diego, Ollikainen, Miina, Domingo, Enric, Ferreira, Ana, ...
In sporadic colorectal tumours the BRAFV600E is associated with microsatellite instability (MSI-H) and inversely associated to KRAS mutations. Tumours from HNPCC patients carrying germline mutations...
Diep, Chieu B, Teixeira, Manuel R, Thorstensen, Lin, Wiig, Johan N, Eknæs, Mette, Nesland, Jahn M, ...
Lind, Guro E, Skotheim, Rolf I, Fraga, Mario F, Abeler, Vera M, Henrique, Rui, Saatcioglu, Fahri, ...
Mesquita, Bárbara, Veiga, Isabel, Pereira, Deolinda, Tavares, Ana, Pinto, Isabel M, Pinto, Carla, ...
Ribeiro, Franclim R, Henrique, Rui, Hektoen, Merete, Berg, Marianne, Jerónimo, Carmen, Teixeira, Manuel R, ...
Telomerase Activity and Genetic Alterations in Primary Breast Carcinomas
Papadopoulou, Anna, Trangas, Theoni, Teixeira, Manuel R, Heim, Sverre, Dimitriadis, Euthimios, Tsarouha, Haroula, ...
It has been proposed that the structural and numerical chromosome abnormalities recorded in breast cancer could be the result of telomere dysfunction and that telomerase is activated de novo to...
Teixeira, Manuel R, Tsarouha, Haroula, Kraggerud, Sigrid M, Pandis, Nikos, Dimitriadis, Euthymios, Andersen, Johan A, ...
Cytogenetically unrelated clones have been detected by chromosome banding analysis in many breast carcinomas. Because these karyotypic studies were performed on short-term cultured samples, it may be...
Diep, Chieu B, Teixeira, Manuel R, Thorstensen, Lin, Wiig, Johan N, Eknæs, Mette, Nesland, Jahn M, ...
Lind, Guro E, Skotheim, Rolf I, Fraga, Mario F, Abeler, Vera M, Henrique, Rui, Saatcioglu, Fahri, ...
Mesquita, Bárbara, Veiga, Isabel, Pereira, Deolinda, Tavares, Ana, Pinto, Isabel M, Pinto, Carla, ...
Telomerase Activity and Genetic Alterations in Primary Breast Carcinomas
Papadopoulou, Anna, Trangas, Theoni, Teixeira, Manuel R, Heim, Sverre, Dimitriadis, Euthimios, Tsarouha, Haroula, ...
It has been proposed that the structural and numerical chromosome abnormalities recorded in breast cancer could be the result of telomere dysfunction and that telomerase is activated de novo to...
Teixeira, Manuel R, Tsarouha, Haroula, Kraggerud, Sigrid M, Pandis, Nikos, Dimitriadis, Euthymios, Andersen, Johan A, ...
Cytogenetically unrelated clones have been detected by chromosome banding analysis in many breast carcinomas. Because these karyotypic studies were performed on short-term cultured samples, it may be...
Ribeiro, Franclim R, Henrique, Rui, Hektoen, Merete, Berg, Marianne, Jerónimo, Carmen, Teixeira, Manuel R, ...
Cerveira, Nuno, Ribeiro, Franclim R, Peixoto, Ana, Costa, Vera, Henrique, Rui, Jerónimo, Carmen, ...
TMPRSS2-ETS gene fusions have been found recurrently in prostate carcinomas, but not in the presumed precursor lesion, high-grade prostatic intraepithelial neoplasia (HGPIN). However, HGPIN lesions...
Quantitative promoter methylation analysis of multiple cancer-related genes in renal cell tumors
Costa, Vera L, Henrique, Rui, Ribeiro, Franclim R, Pinto, Mafalda, Oliveira, Jorge, Lobo, Francisco, ...