Valés-Gómez, Mar, Browne, Helena, Reyburn, Hugh T
Abstract Background Human Cytomegalovirus (HCMV) has acquired through evolution a number of genes to try to evade immune recognition of the virus-infected cell. Many of these mechanisms act to...
Self and viral peptides can initiate lysis by autologous natural killer cells
Mandelboim, Ofer, Wilson, S. Brian, Valés-Gómez, Mar, Reyburn, Hugh T., Strominger, Jack L.
Natural killer (NK) cells are inhibited by specific allotypes of class I major histocompatibility complex ligands recognized by polymorphic inhibitory receptors (e.g., NKIR1 and NKIR2). NK1- and...
Differential binding to HLA-C of p50-activating and p58-inhibitory natural killer cell receptors
Valés-Gómez, Mar, Reyburn, Hugh T., Erskine, Robert A., Strominger, Jack
Natural killer (NK) cell cytotoxicity is regulated in large part by the expression of NK cell receptors able to bind class I major histocompatibility complex glycoproteins. The receptors associated...
The role of zinc in the binding of killer cell Ig-like receptors to class I MHC proteins
Valés-Gómez, Mar, Erskine, Robert A., Deacon, Matthew P., Strominger, Jack L., Reyburn, Hugh T.
The binding of killer cell Ig-like Receptors (KIR) to their Class I MHC ligands was shown previously to be characterized by extremely rapid association and dissociation rate constants. During...
Valés-Gómez, Mar, Shiroishi, Mitsunori, Maenaka, Katsumi, Reyburn, Hugh T.
Human cytomegalovirus carries a gene, UL18, that is homologous to cellular major histocompatibility complex (MHC) class I genes. Like MHC class I molecules, the protein product of the UL18 gene...
Self and viral peptides can initiate lysis by autologous natural killer cells
Mandelboim, Ofer, Wilson, S. Brian, Valés-Gómez, Mar, Reyburn, Hugh T., Strominger, Jack L.
Natural killer (NK) cells are inhibited by specific allotypes of class I major histocompatibility complex ligands recognized by polymorphic inhibitory receptors (e.g., NKIR1 and NKIR2). NK1- and...
Differential binding to HLA-C of p50-activating and p58-inhibitory natural killer cell receptors
Valés-Gómez, Mar, Reyburn, Hugh T., Erskine, Robert A., Strominger, Jack
Natural killer (NK) cell cytotoxicity is regulated in large part by the expression of NK cell receptors able to bind class I major histocompatibility complex glycoproteins. The receptors associated...
The role of zinc in the binding of killer cell Ig-like receptors to class I MHC proteins
Valés-Gómez, Mar, Erskine, Robert A., Deacon, Matthew P., Strominger, Jack L., Reyburn, Hugh T.
The binding of killer cell Ig-like Receptors (KIR) to their Class I MHC ligands was shown previously to be characterized by extremely rapid association and dissociation rate constants. During...
Valés-Gómez, Mar, Shiroishi, Mitsunori, Maenaka, Katsumi, Reyburn, Hugh T.
Human cytomegalovirus carries a gene, UL18, that is homologous to cellular major histocompatibility complex (MHC) class I genes. Like MHC class I molecules, the protein product of the UL18 gene...