Sultan, Marc, Schulz, Marcel H., Hugues, Richard, Magen, Alon, Klingenhoff, Andreas, Scherf, Matthias, ...
The functional complexity of the human transcriptome is not yet fully elucidated. We report a high-throughput sequence of the human transcriptome from a human embryonic kidney and a B cell line. We...
Gene expression variation in Down's syndrome mice allows prioritization of candidate genes (2007)
Sultan, Marc, Piccini, Ilaria, Balzereit, Daniela, Herwig, Ralf, Saran, Nidhi G, Lehrach, Hans, ...
Abstract Background Down's syndrome (DS), or trisomy 21, is a complex developmental disorder that exhibits many clinical signs that vary in occurrence and severity among patients. The molecular...
Quantitative PCR based expression analysis on a nanoliter scale using polymer nano-well chips (2007)
Dahl, Andreas, Sultan, Marc, Jung, Alexander, Schwartz, Regine, Lange, Matthias, Steinwand, Michael, ...
The analysis of gene expression is an essential element of functional genomics. Expression analysis is mainly based on DNA microarrays due to highly parallel readout and high throughput. Quantitative...
Gene expression variation in Down's syndrome mice allows prioritization of candidate genes (2007)
Sultan, Marc, Piccini, Ilaria, Balzereit, Daniela, Herwig, Ralf, Saran, Nidhi G., Lehrach, Hans, ...
Background Down's syndrome (DS), or trisomy 21, is a complex developmental disorder that exhibits many clinical signs that vary in occurrence and severity among patients. The molecular mechanisms...
Taking a functional genomic approach to the study of down syndrome pathogenesos (2007)
Down syndrome (DS) or trisomy 21 is a complex congenital disorder affecting 1:700 live births, and a leading genetic cause of mental retardation. The identification of genes and molecular mechanisms...
Kahlem,Pascal, Sultan,Marc, Herwig,Ralf, Steinfath,Matthias, Balzereit,Daniela, Eppens,Barbara, ...
Human trisomy 21, which results in Down syndrome (DS), is one of the most complicated congenital genetic anomalies compatible with life, yet little is known about the molecular basis of DS. It is...
Kahlem, Pascal, Sultan, Marc, Herwig, Ralf, Steinfath, Matthias, Balzereit, Daniela, Eppens, Barbara, ...
Human trisomy 21, which results in Down syndrome (DS), is one of the most complicated congenital genetic anomalies compatible with life, yet little is known about the molecular basis of DS. It is...
Kahlem, Pascal, Sultan, Marc, Herwig, Ralf, Steinfath, Matthias, Balzereit, Daniela, Eppens, Barbara, ...
Human trisomy 21, which results in Down syndrome (DS), is one of the most complicated congenital genetic anomalies compatible with life, yet little is known about the molecular basis of DS. It is...
Kahlem, Pascal, Sultan, Marc, Herwig, Ralf, Steinfath, Matthias, Balzereit, Daniela, Eppens, Barbara, ...
Human trisomy 21, which results in Down syndrome (DS), is one of the most complicated congenital genetic anomalies compatible with life, yet little is known about the molecular basis of DS. It is...
Kahlem, Pascal, Sultan, Marc, Herwig, Ralf, Steinfath, Matthias, Balzereit, Daniela, Eppens, Barbara, ...
Human trisomy 21, which results in Down syndrome (DS), is one of the most complicated congenital genetic anomalies compatible with life, yet little is known about the molecular basis of DS. It is...
Gene expression variation in Down's syndrome mice allows prioritization of candidate genes
Sultan, Marc, Piccini, Ilaria, Balzereit, Daniela, Herwig, Ralf, Saran, Nidhi G, Lehrach, Hans, ...
RNA from eight Ts65Dn mice (a model of Down syndrome) and eight euploid mice were analysed by real-time PCR to examine inter-individual gene expression levels as a function of trisomy.