Marco Tomasetti

Profiling tumor-associated markers for early detection of malignant mesothelioma: An epidemiologic study (2008)

Amati, Monica, Tomasetti, Marco, Scartozzi, Mario, Mariotti, Laura, Alleva, Renata, Pignotti, Elettra, ...

Improved detection methods for diagnosis of asymptomatic malignant mesothelioma (MM) are essential for an early and reliable detection and treatment of this type of neoplastic disease. Thus, focus...

α-Lipoic acid modulates extracellular matrix and angiogenesis gene expression in non-healing wounds treated with hyperbaric oxygen therapy (2008)

Alleva, Renata, Tomasetti, Marco, Sartini, Davide, Emanuelli, Monica, Nasole, Emanuele, Donato, Ferruccio Di, ...

α-Lipoic acid (LA) has been found previously to accelerate wound repair in patients affected by chronic wounds who underwent hyperbaric oxygen (HBO) therapy. Because proteinases are important in...

Profiling tumor-associated markers for early detection of malignant mesothelioma: An epidemiologic study (2008)

Amati, Monica, Tomasetti, Marco, Scartozzi, Mario, Mariotti, Laura, Alleva, Renata, Pignotti, Elettra, ...

Improved detection methods for diagnosis of asymptomatic malignant mesothelioma (MM) are essential for an early and reliable detection and treatment of this type of neoplastic disease. Thus, focus...

α-Lipoic acid modulates extracellular matrix and angiogenesis gene expression in non-healing wounds treated with hyperbaric oxygen therapy (2008)

Alleva, Renata, Tomasetti, Marco, Sartini, Davide, Emanuelli, Monica, Nasole, Emanuele, Donato, Ferruccio Di, ...

α-Lipoic acid (LA) has been found previously to accelerate wound repair in patients affected by chronic wounds who underwent hyperbaric oxygen (HBO) therapy. Because proteinases are important in...

Profiling tumor-associated markers for early detection of malignant mesothelioma: An epidemiologic study (2008)

Amati, Monica, Tomasetti, Marco, Scartozzi, Mario, Mariotti, Laura, Alleva, Renata, Pignotti, Elettra, ...

Improved detection methods for diagnosis of asymptomatic malignant mesothelioma (MM) are essential for an early and reliable detection and treatment of this type of neoplastic disease. Thus, focus...

α-Lipoic acid modulates extracellular matrix and angiogenesis gene expression in non-healing wounds treated with hyperbaric oxygen therapy (2008)

Alleva, Renata, Tomasetti, Marco, Sartini, Davide, Emanuelli, Monica, Nasole, Emanuele, Donato, Ferruccio Di, ...

α-Lipoic acid (LA) has been found previously to accelerate wound repair in patients affected by chronic wounds who underwent hyperbaric oxygen (HBO) therapy. Because proteinases are important in...

Vitamin E analogs, a novel group of "Mitocans," as anticancer agents: The importance of being redox-silent (2007)

Neuzil, Jiri, Tomasetti, Marco, Zhao, Yan, Dong, Lan-feng, Birringer, Marc, Wang, Xiufang, ...

The search for a selective and efficient anticancer agent for treating all neoplastic disease has yet to deliver a universally suitable compound(s). The majority of established anticancer drugs...

Vitamin E Analogues and Immune Response in Cancer Treatment (2007)

Tomasetti, Marco, Neuzil, Jiri

Chemotherapeutic drugs induce both proliferation arrest and apoptosis; however, some cancer cells escape drug toxicity and become resistant. The suppression of the immune system by chemotherapeutic...

Vitamin E analogs, a novel group of "Mitocans," as anticancer agents: The importance of being redox-silent (2007)

Neuzil, Jiri, Tomasetti, Marco, Zhao, Yan, Dong, Lan-feng, Birringer, Marc, Wang, Xiufang, ...

The search for a selective and efficient anticancer agent for treating all neoplastic disease has yet to deliver a universally suitable compound(s). The majority of established anticancer drugs...

Vitamin E Analogues and Immune Response in Cancer Treatment (2007)

Tomasetti, Marco, Neuzil, Jiri

Chemotherapeutic drugs induce both proliferation arrest and apoptosis; however, some cancer cells escape drug toxicity and become resistant. The suppression of the immune system by chemotherapeutic...

Vitamin E analogs, a novel group of "Mitocans," as anticancer agents: The importance of being redox-silent (2007)

Neuzil, Jiri, Tomasetti, Marco, Zhao, Yan, Dong, Lan-feng, Birringer, Marc, Wang, Xiufang, ...

The search for a selective and efficient anticancer agent for treating all neoplastic disease has yet to deliver a universally suitable compound(s). The majority of established anticancer drugs...

Vitamin E Analogues and Immune Response in Cancer Treatment (2007)

Tomasetti, Marco, Neuzil, Jiri

Chemotherapeutic drugs induce both proliferation arrest and apoptosis; however, some cancer cells escape drug toxicity and become resistant. The suppression of the immune system by chemotherapeutic...

Vitamin E analogues as anti-cancer agents: Lessons from studies with α-tocopheryl succinate (2006)

Wang, Xiufang, Dong, Lan-feng, Zhao, Yan, Tomasetti, Marco, Wu, Kun, Neuzil, Jiri

The new millennium has witnessed considerable decrease in a number of previously fatal pathologies, largely due to the advancement in molecular medicine and modern approaches to treatment. In spite...

Vitamin E analogues as anti-cancer agents: Lessons from studies with a-tocopheryl succinate (2006)

Wang, Xiufang, Dong, Lan-feng, Zhao, Yan, Tomasetti, Marco, Wu, Kun, Neuzil, Jiri

Yes

Vitamin E analogues as anti-cancer agents: Lessons from studies with α-tocopheryl succinate (2006)

Wang, Xiufang, Dong, Lan-feng, Zhao, Yan, Tomasetti, Marco, Wu, Kun, Neuzil, Jiri

The new millennium has witnessed considerable decrease in a number of previously fatal pathologies, largely due to the advancement in molecular medicine and modern approaches to treatment. In spite...

Vitamin E analogues as anti-cancer agents: The role of modulation of apoptosis signalling pathways (2006)

Neuzil, Jiri, Dong, Lan-Feng, Wang, Xiu-Fang, Zhao, Yan, Tomasetti, Marco, Wu, Kun

Yes

Vitamin E analogues as anti-cancer agents: The role of modulation of apoptosis signalling pathways (2006)

Neuzil, Jiri, Dong, Lan-Feng, Wang, Xiu-Fang, Zhao, Yan, Tomasetti, Marco, Wu, Kun

α-Tocopheryl succinate alters cell cycle distribution sensitising human osteosarcoma cells to methotrexate-induced apoptosis (2006)

Alleva, Renata, Benassi, Maria Serena, Pazzaglia, Laura, Tomasetti, Marco, Gellert, Nina, Borghi, Battista, ...

α-Tocopheryl succinate (α-TOS) exerts pleiotrophic responses in malignant cells leading to cell cycle arrest, differentiation and apoptosis. We tested the ability of α-TOS to induce apoptosis or...

α-Tocopheryl succinate induces DR4 and DR5 expression by a p53-dependent route: Implication for sensitisation of resistant cancer cells to TRAIL apoptosis (2006)

Tomasetti, Marco, Andera, Ladislav, Alleva, Renata, Borghi, Battista, Neuzil, Jiri, Procopio, Antonio

We evaluated the ability of α-tocopheryl succinate (α-TOS) to sensitise TRAIL-resistant malignant mesothelioma (MM) cells to TRAIL-induced apoptosis. We show that α-TOS activates expression of...

α-Tocopheryl succinate alters cell cycle distribution sensitising human osteosarcoma cells to methotrexate-induced apoptosis (2006)

Alleva, Renata, Benassi, Maria Serena, Pazzaglia, Laura, Tomasetti, Marco, Gellert, Nina, Borghi, Battista, ...

α-Tocopheryl succinate (α-TOS) exerts pleiotrophic responses in malignant cells leading to cell cycle arrest, differentiation and apoptosis. We tested the ability of α-TOS to induce apoptosis or...

α-Tocopheryl succinate induces DR4 and DR5 expression by a p53-dependent route: Implication for sensitisation of resistant cancer cells to TRAIL apoptosis (2006)

Tomasetti, Marco, Andera, Ladislav, Alleva, Renata, Borghi, Battista, Neuzil, Jiri, Procopio, Antonio

We evaluated the ability of α-tocopheryl succinate (α-TOS) to sensitise TRAIL-resistant malignant mesothelioma (MM) cells to TRAIL-induced apoptosis. We show that α-TOS activates expression of...

Vitamin E analogues as anti-cancer agents: Lessons from studies with α-tocopheryl succinate (2006)

Wang, Xiufang, Dong, Lan-feng, Zhao, Yan, Tomasetti, Marco, Wu, Kun, Neuzil, Jiri

The new millennium has witnessed considerable decrease in a number of previously fatal pathologies, largely due to the advancement in molecular medicine and modern approaches to treatment. In spite...

Vitamin E analogues as anti-cancer agents: The role of modulation of apoptosis signalling pathways (2006)

Neuzil, Jiri, Dong, Lan-Feng, Wang, Xiu-Fang, Zhao, Yan, Tomasetti, Marco, Wu, Kun

α-Tocopheryl succinate alters cell cycle distribution sensitising human osteosarcoma cells to methotrexate-induced apoptosis (2006)

Alleva, Renata, Benassi, Maria Serena, Pazzaglia, Laura, Tomasetti, Marco, Gellert, Nina, Borghi, Battista, ...

α-Tocopheryl succinate (α-TOS) exerts pleiotrophic responses in malignant cells leading to cell cycle arrest, differentiation and apoptosis. We tested the ability of α-TOS to induce apoptosis or...

α-Tocopheryl succinate induces DR4 and DR5 expression by a p53-dependent route: Implication for sensitisation of resistant cancer cells to TRAIL apoptosis (2006)

Tomasetti, Marco, Andera, Ladislav, Alleva, Renata, Borghi, Battista, Neuzil, Jiri, Procopio, Antonio

We evaluated the ability of α-tocopheryl succinate (α-TOS) to sensitise TRAIL-resistant malignant mesothelioma (MM) cells to TRAIL-induced apoptosis. We show that α-TOS activates expression of...

a-Tocopheryl succinate induces cytostasis and apoptosis in osteosarcoma cells: the role of E2F1 (2005)

Alleva, Renata, Benassi, Maria Serena, Tomasetti, Marco, Gellert, Nina, Ponticelli, Francesca, Borgha, Battista, ...

Yes

a-Lipoic acid supplementation inhibits oxidative damage accelerating chronic wound healing in patients undergoing hyperbaric oxygen therapy (2005)

Alleva, Renata, Nasole, Emmanuele, Donato, Ferruccio Di, Borghi, Battista, Neuzil, Jiri, Tomasetti, Marco

Yes

a-Tocopheryl succinate inhibits malignant mesothelioma by disrupting the Fibroblast Growth Factor Autocrine Loop: Mechanism and the role of oxidative stress (2005)

Stapelberg, Michael, Gellert, Nina, Swettenham, Emma Angela, Tomasetti, Marco, Witting, Paul K., Procopio, Antonio, ...

Yes

α-Tocopheryl succinate induces cytostasis and apoptosis in osteosarcoma cells: the role of E2F1 (2005)

Alleva, Renata, Benassi, Maria Serena, Tomasetti, Marco, Gellert, Nina, Ponticelli, Francesca, Borgha, Battista, ...

Yes

α-Lipoic acid supplementation inhibits oxidative damage accelerating chronic wound healing in patients undergoing hyperbaric oxygen therapy (2005)

Alleva, Renata, Nasole, Emmanuele, Donato, Ferruccio Di, Borghi, Battista, Neuzil, Jiri, Tomasetti, Marco

Hyperbaric oxygen (HBO) therapy is successfully used for the treatment of a variety of conditions. However, prolonged exposure to high concentrations of oxygen induces production of reactive oxygen...

α-Tocopheryl succinate inhibits malignant mesothelioma by disrupting the Fibroblast Growth Factor Autocrine Loop: Mechanism and the role of oxidative stress (2005)

Stapelberg, Michael, Gellert, Nina, Cowie, Emma Angela, Tomasetti, Marco, Witting, Paul K., Procopio, Antonio, ...

We have studied the potential effect against human malignant mesotheliomas (MM) of α-tocopheryl succinate (α-TOS), a redox-silent vitamin E analog with strong pro-apoptotic and anti-cancer...

α-Tocopheryl succinate induces cytostasis and apoptosis in osteosarcoma cells: the role of E2F1 (2005)

Alleva, Renata, Benassi, Maria Serena, Tomasetti, Marco, Gellert, Nina, Ponticelli, Francesca, Borgha, Battista, ...

α-Lipoic acid supplementation inhibits oxidative damage accelerating chronic wound healing in patients undergoing hyperbaric oxygen therapy (2005)

Alleva, Renata, Nasole, Emmanuele, Donato, Ferruccio Di, Borghi, Battista, Neuzil, Jiri, Tomasetti, Marco

Hyperbaric oxygen (HBO) therapy is successfully used for the treatment of a variety of conditions. However, prolonged exposure to high concentrations of oxygen induces production of reactive oxygen...

α-Tocopheryl succinate inhibits malignant mesothelioma by disrupting the Fibroblast Growth Factor Autocrine Loop: Mechanism and the role of oxidative stress (2005)

Stapelberg, Michael, Gellert, Nina, Cowie, Emma Angela, Tomasetti, Marco, Witting, Paul K., Procopio, Antonio, ...

We have studied the potential effect against human malignant mesotheliomas (MM) of α-tocopheryl succinate (α-TOS), a redox-silent vitamin E analog with strong pro-apoptotic and anti-cancer...

α-Tocopheryl succinate induces cytostasis and apoptosis in osteosarcoma cells: the role of E2F1 (2005)

Alleva, Renata, Benassi, Maria Serena, Tomasetti, Marco, Gellert, Nina, Ponticelli, Francesca, Borgha, Battista, ...

α-Tocopheryl succinate (α-TOS), a redox-inactive analog of vitamin E, induces cell cycle arrest, differentiation, and triggers apoptosis. We examined the ability of α-TOS to induce cytostasis...

α-Lipoic acid supplementation inhibits oxidative damage accelerating chronic wound healing in patients undergoing hyperbaric oxygen therapy (2005)

Alleva, Renata, Nasole, Emmanuele, Donato, Ferruccio Di, Borghi, Battista, Neuzil, Jiri, Tomasetti, Marco

Hyperbaric oxygen (HBO) therapy is successfully used for the treatment of a variety of conditions. However, prolonged exposure to high concentrations of oxygen induces production of reactive oxygen...

α-Tocopheryl succinate inhibits malignant mesothelioma by disrupting the Fibroblast Growth Factor Autocrine Loop: Mechanism and the role of oxidative stress (2005)

Stapelberg, Michael, Gellert, Nina, Cowie, Emma Angela, Tomasetti, Marco, Witting, Paul K., Procopio, Antonio, ...

We have studied the potential effect against human malignant mesotheliomas (MM) of α-tocopheryl succinate (α-TOS), a redox-silent vitamin E analog with strong pro-apoptotic and anti-cancer...

A vitamin E analogue suppresses malignant mesothelioma in a preclinical model: a future drug against a fatal neoplastic disease? (2004)

Tomasetti, Marco, Gellert, Nina, Procopio, Antonio, Neuzil, Jiri

Yes

alpha-Tocopheryl succinate inhibits proliferation of mesothelioma cells by differential down-regulation of fibroblast growth factor receptors (2004)

Stapelberg, Michael, Tomasetti, Marco, Alleva, Renata, Gellert, Nina, Procopio, Antonio, Neuzil, Jiri, ...

Yes

Vitamin E analogues: a new class of inducers of apoptosis with selective anti-cancer effects (2004)

Neuzil, Jiri, Tomasetti, Marco, Mellick, Albert, Alleva, Renata, Salvatore, Brian A., Birringer, Marc, ...

Yes

A vitamin E analogue suppresses malignant mesothelioma in a preclinical model: a future drug against a fatal neoplastic disease? (2004)

Tomasetti, Marco, Gellert, Nina, Procopio, Antonio, Neuzil, Jiri

Yes

α-Tocopheryl succinate inhibits proliferation of mesothelioma cells by selective down-regulation of fibroblast growth factor receptors (2004)

Stapelberg, Michael, Tomasetti, Marco, Alleva, Renata, Gellert, Nina, Procopio, Antonio, Neuzil, Jiri

α-Tocopheryl succinate (α-TOS), a redox-silent analogue of vitamin E, inhibits malignant mesotheliomas (MM) in a pre-clinical model. Here we investigated the underlying mechanism. Exposure of MM...

Vitamin E analogues: a new class of inducers of apoptosis with selective anti-cancer effects (2004)

Neuzil, Jiri, Tomasetti, Marco, Mellick, Albert Sleiman, Alleva, Renata, Salvatore, Brian A., Birringer, Marc, ...

Yes

A vitamin E analogue suppresses malignant mesothelioma in a preclinical model: a future drug against a fatal neoplastic disease? (2004)

Tomasetti, Marco, Gellert, Nina, Procopio, Antonio, Neuzil, Jiri

α-Tocopheryl succinate inhibits proliferation of mesothelioma cells by selective down-regulation of fibroblast growth factor receptors (2004)

Stapelberg, Michael, Tomasetti, Marco, Alleva, Renata, Gellert, Nina, Procopio, Antonio, Neuzil, Jiri

α-Tocopheryl succinate (α-TOS), a redox-silent analogue of vitamin E, inhibits malignant mesotheliomas (MM) in a pre-clinical model. Here we investigated the underlying mechanism. Exposure of MM...

Vitamin E analogues: a new class of inducers of apoptosis with selective anti-cancer effects (2004)

Neuzil, Jiri, Tomasetti, Marco, Mellick, Albert Sleiman, Alleva, Renata, Salvatore, Brian A., Birringer, Marc, ...

A vitamin E analogue suppresses malignant mesothelioma in a preclinical model: a future drug against a fatal neoplastic disease? (2004)

Tomasetti, Marco, Gellert, Nina, Procopio, Antonio, Neuzil, Jiri

α-Tocopheryl succinate inhibits proliferation of mesothelioma cells by selective down-regulation of fibroblast growth factor receptors (2004)

Stapelberg, Michael, Tomasetti, Marco, Alleva, Renata, Gellert, Nina, Procopio, Antonio, Neuzil, Jiri

α-Tocopheryl succinate (α-TOS), a redox-silent analogue of vitamin E, inhibits malignant mesotheliomas (MM) in a pre-clinical model. Here we investigated the underlying mechanism. Exposure of MM...

Vitamin E analogues: a new class of inducers of apoptosis with selective anti-cancer effects (2004)

Neuzil, Jiri, Tomasetti, Marco, Mellick, Albert Sleiman, Alleva, Renata, Salvatore, Brian A., Birringer, Marc, ...

In spite of unrelenting effort, the net incidence of neoplastic diseases appears not to have been curbed. While some types of cancer have been suppressed significantly, others are either stagnating...

Lymphocyte DNA damage precedes DNA repair or cell death after orthopaedic surgery under general anaesthesia (2003)

Alleva, Renata, Tomasetti, Marco, Solenghi, Maria D., Stagni, Francesca, Gamberini, Flavio, Bassi, Alessandra, ...

Anaesthetics have gained a lot of attention for their potential mutagenic/carcinogenic effects. In the present study we have investigated the genotoxicity of the inhalation anaesthetic sevoflurane on...

α-Lipoic Acid Modulates Extracellular Matrix and Angiogenesis Gene Expression in Non-Healing Wounds Treated with Hyperbaric Oxygen Therapy

Alleva, Renata, Tomasetti, Marco, Sartini, Davide, Emanuelli, Monica, Nasole, Emanuele, Di Donato, Ferruccio, ...

α-Lipoic acid (LA) has been found previously to accelerate wound repair in patients affected by chronic wounds who underwent hyperbaric oxygen (HBO) therapy. Because proteinases are important in...