Noyes, Marcus B., Christensen, Ryan G., Wakabayashi, Atsuya, Stormo, Gary D., Brodsky, Michael H., Wolfe, Scot A.
We describe the comprehensive characterization of homeodomain DNA-binding specificities from a metazoan genome. The analysis of all 84 independent homeodomains from D. melanogaster reveals the...
Targeted gene inactivation in zebrafish using engineered zinc-finger nucleases (2008)
Meng, Xiangdong, Noyes, Marcus B., Zhu, Lihua J., Lawson, Nathan D., Wolfe, Scot A.
Direct genomic manipulation at a specific locus is still not feasible in most vertebrate model organisms. In vertebrate cell lines, genomic lesions at a specific site have been introduced using...
Noyes, Marcus B., Meng, Xiangdong, Wakabayashi, Atsuya, Sinha, Saurabh, Brodsky, Michael H., Wolfe, Scot A.
Specificity data for groups of transcription factors (TFs) in a common regulatory network can be used to computationally identify the location of cis-regulatory modules in a genome. The primary...
Noyes, Marcus B., Meng, Xiangdong, Wakabayashi, Atsuya, Sinha, Saurabh, Brodsky, Michael H., Wolfe, Scot A.
Specificity data for groups of transcription factors (TFs) in a common regulatory network can be used to computationally identify the location of cis-regulatory modules in a genome. The primary...
Noyes, Marcus B., Meng, Xiangdong, Wakabayashi, Atsuya, Sinha, Saurabh, Brodsky, Michael H., Wolfe, Scot A.
Specificity data for groups of transcription factors (TFs) in a common regulatory network can be used to computationally identify the location of cis-regulatory modules in a genome. The primary...