Marcus Harrison

Comprehensive identification of essential Staphylococcus aureusgenes using Transposon-Mediated Differential Hybridisation (TMDH) (2009)

Chaudhuri, Roy R, Allen, Andrew G, Owen, Paul J, Shalom, Gil, Stone, Karl, Harrison, Marcus, ...

Abstract Background In recent years there has been an increasing problem with Staphylococcus aureus strains that are resistant to treatment with existing antibiotics. An important starting point for...

Development and application of versatile high density microarrays for genome-wide analysis of Streptomyces coelicolor: characterization of the HspR regulon (2009)

Bucca, Giselda, Laing, Emma, Mersinias, Vassilis, Allenby, Nicholas, Hurd, Douglas, Holdstock, Jolyon, ...

Abstract Background DNA microarrays are a key resource for global analysis of genome content, gene expression and the distribution of transcription factor binding sites. We describe the development...

H-NS Mediates the Silencing of Laterally Acquired Genes in Bacteria (2006)

Sacha Lucchini, Gary Rowley, Martin D. Goldberg, Douglas Hurd, Marcus Harrison

Histone-like nucleoid structuring protein (H-NS) is a modular protein that is associated with the bacterial nucleoid. We used chromatin immunoprecipitation to determine the binding sites of H-NS and...

Studies of the distribution of Escherichia coli cAMP-receptor protein and RNA polymerase along the E. coli chromosome

Grainger, David C., Hurd, Douglas, Harrison, Marcus, Holdstock, Jolyon, Busby, Stephen J. W.

Chromatin immunoprecipitation and high-density microarrays have been used to monitor the distribution of the global transcription regulator Escherichia coli cAMP-receptor protein (CRP) and RNA...

H-NS Mediates the Silencing of Laterally Acquired Genes in Bacteria

Lucchini, Sacha, Rowley, Gary, Goldberg, Martin D, Hurd, Douglas, Harrison, Marcus, Hinton, Jay C. D

Histone-like nucleoid structuring protein (H-NS) is a modular protein that is associated with the bacterial nucleoid. We used chromatin immunoprecipitation to determine the binding sites of H-NS and...

Studies of the distribution of Escherichia coli cAMP-receptor protein and RNA polymerase along the E. coli chromosome

Grainger, David C., Hurd, Douglas, Harrison, Marcus, Holdstock, Jolyon, Busby, Stephen J. W.

Chromatin immunoprecipitation and high-density microarrays have been used to monitor the distribution of the global transcription regulator Escherichia coli cAMP-receptor protein (CRP) and RNA...

H-NS Mediates the Silencing of Laterally Acquired Genes in Bacteria

Lucchini, Sacha, Rowley, Gary, Goldberg, Martin D, Hurd, Douglas, Harrison, Marcus, Hinton, Jay C. D

Histone-like nucleoid structuring protein (H-NS) is a modular protein that is associated with the bacterial nucleoid. We used chromatin immunoprecipitation to determine the binding sites of H-NS and...

Development and application of versatile high density microarrays for genome-wide analysis of Streptomyces coelicolor: characterization of the HspR regulon

Bucca, Giselda, Laing, Emma, Mersinias, Vassilis, Allenby, Nicholas, Hurd, Douglas, Holdstock, Jolyon, ...

Development of high-density microarrays for global analysis of gene expression and transcription factor binding in Streptomyces coelicolor suggests a novel role for HspR in stress adaptation.