Southern, Louise, Williams, Jonathan, Esiri, Margaret M
Abstract Background Advanced glycation end-products (AGEs) and their receptor (RAGE) occur in dementia of the Alzheimer's type and diabetic microvascular disease. Accumulation of AGEs relates to risk...
Lai, Mitchell K.P., Tsang, Shirley W.Y., Garcia-Alloza, Monica, Minger, Stephen L., Nicoll, James A.R., Esiri, Margaret M., ...
The effects of the APOE epsilon 4 allele on a range of pre- and postsynaptic cholinergic markers were studied in a cohort of community-based Alzheimer's disease (AD) patients. Compared with...
Haplotype-specific expression of exon 10 at the human MAPT locus (2006)
Caffrey, Tara M., Joachim, Catharine, Paracchini, Silvia, Esiri, Margaret M., Wade-Martins, Richard
Neurofibrillary tangles composed of exon 10+ microtubule associated protein tau (MAPT) deposits are the characteristic feature of the neurodegenerative diseases progressive supranuclear palsy (PSP)...
Haplotype-specific expression of exon 10 at the human MAPT locus (2006)
Caffrey, Tara M., Joachim, Catharine, Paracchini, Silvia, Esiri, Margaret M., Wade-Martins, Richard
Neurofibrillary tangles composed of exon 10+ microtubule associated protein tau (MAPT) deposits are the characteristic feature of the neurodegenerative diseases progressive supranuclear palsy (PSP)...
Pomeroy, Ian M., Matthews, Paul M., Frank, Joseph A., Jordan, Elaine K., Esiri, Margaret M.
The use of immunohistochemical methods has led to a new understanding of the prevalence and significance of cortical lesions in multiple sclerosis but these lesions have not yet been formally...
Pomeroy, Ian M., Matthews, Paul M., Frank, Joseph A., Jordan, Elaine K., Esiri, Margaret M.
The use of immunohistochemical methods has led to a new understanding of the prevalence and significance of cortical lesions in multiple sclerosis but these lesions have not yet been formally...
Highley, J. Robin, Walker, Mary A., Esiri, Margaret M., Crow, Timothy J., Harrison, Paul J.
The uncinate fasciculus interconnects the anterior temporal and inferior frontal lobes. The temporal lobes show a number of anatomical asymmetries, some of which are altered in schizophrenia. This...
Neuroimaging Alzheimer's Disease (2002)
Margaret M. Esiri, Michael S. Mega, Paul M.Thompson, James H. Morris, Arthur W. Toga, ...
nd time. They detect group-specific features not apparent in individual patients' scans. Once built, these atlases can be stratified into subpopulations to reflect a particular clinical group,...
Highley, J. Robin, Walker, Mary A., Esiri, Margaret M., Crow, Timothy J., Harrison, Paul J.
The uncinate fasciculus interconnects the anterior temporal and inferior frontal lobes. The temporal lobes show a number of anatomical asymmetries, some of which are altered in schizophrenia. This...
Minger, Stephen L., Honer, William G., Esiri, Margaret M., McDonald, Brendan, Keene, Janet, Nicoll, James A.R., ...
Synaptic pathology is proposed to be integral to the clinical expression of Alzheimer disease (AD). Most studies have assessed only the vesicle protein synaptophysin as a measure of synaptic...
Highley, J. Robin, Esiri, Margaret M., McDonald, Brendan, Cortina-Borja, Mario, Herron, Brian M., Crow, Timothy J.
In this study the cross-sectional area (in n = 14 female controls, 15 male controls, 11 female patients with schizophrenia, 15 male patients with schizophrenia) and fibre composition (in n ...
MCCALLUM, KIMBERLI, ESIRI, MARGARET M., TOURTELLOTTE, WALLACE W., BOOSS, JOHN
This report provides a quantitative analysis of the distribution of helper-inducer T cells (H-I, LEU3A +) and cytotoxic-suppressor T cells (C-S, 0KT8 +) performed in a standardized fashion...
Axonal Injury in Cerebral Malaria
Medana, Isabelle M., Day, Nicholas P., Hien, Tran Tinh, Mai, Nguyen Thi Hoang, Bethell, Delia, Phu, Nguyen Hoan, ...
Impairment of consciousness and other signs of cerebral dysfunction are common complications of severe Plasmodium falciparum malaria. Although the majority of patients make a complete recovery a...
Lymphocyte sensitivity to skeletal muscle in patients with polymyositis and other disorders
Esiri, Margaret M., Maclennan, I. C. M., Hazleman, B. L.
The transformation response of peripheral blood lymphocytes in vitro to human muscle antigen has been studied in patients with polymyositis, polymyalgia rheumatica and rheumatoid arthritis....
Esiri, Margaret M., Maclennan, I. C. M.
An allergic myositis was produced in an inbred strain of rats by giving repeated injections of heterologous muscle with complete Freund's adjuvant. Histological lesions developed after two or more...
Tzartos, John S., Friese, Manuel A., Craner, Matthew J., Palace, Jackie, Newcombe, Jia, Esiri, Margaret M., ...
Recent findings in the animal model for multiple sclerosis (MS), experimental autoimmune encephalomyelitis, implicate a novel CD4+ T-cell subset (TH17), characterized by the secretion of...
Alpha-synuclein pathology in the olfactory pathways of dementia patients
Hubbard, Paul S, Esiri, Margaret M, Reading, Margaret, McShane, Rupert, Nagy, Zsuzsanna
Lewy-type pathology is a characteristic of a number of neurodegenerative disorders, including Parkinson's disease and dementia with Lewy bodies. Thus far, the definitive diagnosis of these dementias...