Epithelial NEMO links innate immunity to chronic intestinal inflammation (2007)
Nenci, Arianna, Becker, Christoph, Wullaert, Andy, Gareus, Ralph, Van Loo, Geert, Danese, Silvio, ...
Deregulation of intestinal immune responses seems to have a principal function in the pathogenesis of inflammatory bowel disease(1-4). The gut epithelium is critically involved in the maintenance of...
Nenci, Arianna, Huth, Marion, Funteh, Alfred, Schmidt-Supprian, Marc, Bloch, Wilhelm, Metzger, Daniel, ...
NF-κB essential modulator (NEMO), the regulatory subunit of the IκB kinase, is essential for NF-κB activation. Mutations disrupting the X-linked NEMO gene cause incontinentia pigmenti (IP), a...
Nenci, Arianna, Huth, Marion, Funteh, Alfred, Schmidt-Supprian, Marc, Bloch, Wilhelm, Metzger, Daniel, ...
NF-κB Essential Modulator (NEMO), the regulatory subunit of the IκB kinase, is essential for NF-κB activation. Mutations disrupting the X-linked NEMO gene cause incontinentia pigmenti (IP), a...
Conditional disruption of IκB kinase 2 fails to prevent obesity-induced insulin resistance
Röhl, Mathias, Pasparakis, Manolis, Baudler, Stephanie, Baumgartl, Julia, Gautam, Dinesh, Huth, Marion, ...
The inhibitor of NF-κB (IκB) kinases (IKK1[α] and IKK2[β]), the catalytic subunits of the IKK complex, phosphorylate IκB proteins on serine residues, targeting them for degradation and thus...
Conditional disruption of IκB kinase 2 fails to prevent obesity-induced insulin resistance
Röhl, Mathias, Pasparakis, Manolis, Baudler, Stephanie, Baumgartl, Julia, Gautam, Dinesh, Huth, Marion, ...
The inhibitor of NF-κB (IκB) kinases (IKK1[α] and IKK2[β]), the catalytic subunits of the IKK complex, phosphorylate IκB proteins on serine residues, targeting them for degradation and thus...