Multi-tissue coexpression networks reveal unexpected subnetworks associated with disease (2009)
Dobrin, Radu, Zhu, Jun, Molony, Cliona, Argman, Carmen, Parrish, Mark L, Carlson, Sonia, ...
Abstract Background Obesity is a particularly complex disease that at least partially involves genetic and environmental perturbations to gene-networks connecting the hypothalamus and several...
Dobrin, Radu, Zhu, Jun, Molony, Cliona, Argman, Carmen, Parrish, Mark L, Carlson, Sonia, ...
Figure S1 shows the connectivity distribution P(k) for GGC networks. Figure S2 shows FDR curves for each tissue in the analysis. Figure S3 shows modules in single tissue GGC networks as detected by...
Castle, John, Garrett-Engele, Phil, Armour, Christopher D, Duenwald, Sven J, Loerch, Patrick M, Meyer, Michael R, ...
Abstract Microarrays offer a high-resolution means for monitoring pre-mRNA splicing on a genomic scale. We have developed a novel, unbiased amplification protocol that permits labeling of entire...
Castle, John, Garrett-Engele, Phil, Armour, Christopher D, Duenwald, Sven J, Loerch, Patrick M, Meyer, Michael R, ...
A novel, unbiased amplification protocol has been developed that permits labeling of entire transcripts. Also, hybridization conditions, probe characteristics, and analysis algorithms were optimized...
Loertscher, Jennifer, Larson, Lynnelle L., Matson, Clinton K., Parrish, Mark L., Felthauser, Alicia, Sturm, Aaron, ...
Endoplasmic reticulum-associated degradation (ERAD) mediates the turnover of short-lived and misfolded proteins in the ER membrane or lumen. In spite of its important role, only subtle growth...
Koning, Ann J, Larson, Lynnelle L, Cadera, Emily J, Parrish, Mark L, Wright, Robin L
In yeast, increased levels of the sterol biosynthetic enzyme, 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase isozyme, Hmg1p, induce assembly of nuclear-associated ER membranes called...
Castle, John, Garrett-Engele, Phil, Armour, Christopher D, Duenwald, Sven J, Loerch, Patrick M, Meyer, Michael R, ...
A novel, unbiased amplification protocol has been developed that permits labeling of entire transcripts. Also, hybridization conditions, probe characteristics, and analysis algorithms were optimized...
Loertscher, Jennifer, Larson, Lynnelle L., Matson, Clinton K., Parrish, Mark L., Felthauser, Alicia, Sturm, Aaron, ...
Endoplasmic reticulum-associated degradation (ERAD) mediates the turnover of short-lived and misfolded proteins in the ER membrane or lumen. In spite of its important role, only subtle growth...
Koning, Ann J, Larson, Lynnelle L, Cadera, Emily J, Parrish, Mark L, Wright, Robin L
In yeast, increased levels of the sterol biosynthetic enzyme, 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase isozyme, Hmg1p, induce assembly of nuclear-associated ER membranes called...
Multi-tissue coexpression networks reveal unexpected subnetworks associated with disease
Dobrin, Radu, Zhu, Jun, Molony, Cliona, Argman, Carmen, Parrish, Mark L, Carlson, Sonia, ...
Tissue-to-tissue coexpression networks between genes in hypothalamus, liver or adipose tissue enable identification of obesity-specific genes.