Reijmers, Leon G., Coats, Jennifer K., Pletcher, Mathew T., Wiltshire, Tim, Tarantino, Lisa M., Mayford, Mark
Targeted mutagenesis in mice has shown that genes from a wide variety of gene families are involved in memory formation. The efficient identification of genes involved in learning and memory could be...
Krestel,Heinz Eric, Mayford,Mark, Seeburg,Peter H., Sprengel,Rolf
Doxycycline (Dox)-sensitive co-regulation of two transcriptionally coupled transgenes was investigated in the mouse. For this, we generated four independent mouse lines carrying coding regions for...
Krestel, Heinz Eric, Mayford, Mark, Seeburg, Peter H., Sprengel, Rolf
Doxycycline (Dox)-sensitive co-regulation of two transcriptionally coupled transgenes was investigated in the mouse. For this, we generated four independent mouse lines carrying coding regions for...
Rescuing impairment of long-term potentiation in fyn-deficient mice by introducing Fyn transgene
Kojima, Nobuhiko, Wang, Jian, Mansuy, Isabelle M., Grant, Seth G. N., Mayford, Mark, Kandel, Eric R.
To examine the physiological role of the Fyn tyrosine kinase in neurons, we generated transgenic mice that expressed a fyn cDNA under the control of the calcium/calmodulin-dependent protein kinase...
Mayford, Mark, Baranes, Danny, Podsypanina, Katrina, Kandel, Eric R.
Neuronal signaling requires that synaptic proteins be appropriately localized within the cell and regulated there. In mammalian neurons, polyribosomes are found not just in the cell body, but also in...
Regional and strain-specific gene expression mapping in the adult mouse brain
Sandberg, Rickard, Yasuda, Rie, Pankratz, Daniel G., Carter, Todd A., Del Rio, Jo A., Wodicka, Lisa, ...
To determine the genetic causes and molecular mechanisms responsible for neurobehavioral differences in mice, we used highly parallel gene expression profiling to detect genes that are differentially...
Rescuing impairment of long-term potentiation in fyn-deficient mice by introducing Fyn transgene
Kojima, Nobuhiko, Wang, Jian, Mansuy, Isabelle M., Grant, Seth G. N., Mayford, Mark, Kandel, Eric R.
To examine the physiological role of the Fyn tyrosine kinase in neurons, we generated transgenic mice that expressed a fyn cDNA under the control of the calcium/calmodulin-dependent protein kinase...
Mayford, Mark, Baranes, Danny, Podsypanina, Katrina, Kandel, Eric R.
Neuronal signaling requires that synaptic proteins be appropriately localized within the cell and regulated there. In mammalian neurons, polyribosomes are found not just in the cell body, but also in...
Regional and strain-specific gene expression mapping in the adult mouse brain
Sandberg, Rickard, Yasuda, Rie, Pankratz, Daniel G., Carter, Todd A., Del Rio, Jo A., Wodicka, Lisa, ...
To determine the genetic causes and molecular mechanisms responsible for neurobehavioral differences in mice, we used highly parallel gene expression profiling to detect genes that are differentially...
Reijmers, Leon G., Coats, Jennifer K., Pletcher, Mathew T., Wiltshire, Tim, Tarantino, Lisa M., Mayford, Mark
Targeted mutagenesis in mice has shown that genes from a wide variety of gene families are involved in memory formation. The efficient identification of genes involved in learning and memory could be...
Barros, Claudia S., Calabrese, Barbara, Chamero, Pablo, Roberts, Amanda J., Korzus, Ed, Lloyd, Kent, ...
Neuregulin-1 (NRG1) and its ErbB2/B4 receptors are encoded by candidate susceptibility genes for schizophrenia, yet the essential functions of NRG1 signaling in the CNS are still unclear. Using...