Mark Reimers

An analytical pipeline for genomic representations used for cytosine methylation studies (2008)

Thompson, Reid F., Reimers, Mark, Khulan, Batbayar, Gissot, Mathieu, Richmond, Todd A., Chen, Quan, ...

Motivation: Representations of the genome can be generated by the selection of a subpopulation of restriction fragments using ligation-mediated PCR. Such representations form the basis for a number...

Clonal Mosaic Model for the Synthesis of Mammalian Coat Patterns (2007)

Accepted For Graphics, Marcelo Walter, Alain Fournier, Mark Reimers

We introduce the Clonal Mosaic (CM) model for the synthesis of mammalian coat patterns, present its implementation for modeling and display purposes, and give a few examples of generated patterns....

The LeFE algorithm: embracing the complexity of gene expression in the interpretation of microarray data (2007)

Eichler, Gabriel S, Reimers, Mark, Kane, David, Weinstein, John N

Abstract Interpretation of microarray data remains a challenge, and most methods fail to consider the complex, nonlinear regulation of gene expression. To address that limitation, we introduce...

Exploring the Foundation of Genomics: A Northern Blot Reference set for the Comparative Analysis of Transcript Profiling Technologies (2006)

Danielle Kemmer, Margareta Faxén, Emily Hodges, Jonathan Lim, Elena Herzog, Elsebrit Ljungström, ...

In this paper we aim to create a reference data collection of Northern blot results and demonstrate how such a collection can enable a quantitative comparison of modern expression profiling...

High-Throughput GoMiner, an 'industrial-strength' integrative gene ontology tool for interpretation of multiple-microarray experiments, with application to studies of Common Variable Immune Deficiency (CVID) (2005)

Zeeberg, Barry R, Qin, Haiying, Narasimhan, Sudarshan, Sunshine, Margot, Cao, Hong, Kane, David W, ...

Abstract Background We previously developed GoMiner, an application that organizes lists of 'interesting' genes (for example, under-and overexpressed genes from a microarray experiment) for...

Quality assessment of microarrays: Visualization of spatial artifacts and quantitation of regional biases (2005)

Reimers, Mark, Weinstein, John N

Abstract Background Quality-control is an important issue in the analysis of gene expression microarrays. One type of problem is regional bias, in which one region of a chip shows artifactually high...

BMC Bioinformatics BioMed Central Methodology article Quality assessment of microarrays: Visualization of spatial artifacts and quantitation of regional biases (2005)

Mark Reimers, John N Weinstein, Mark Reimers, John N Weinstein

Background: Quality-control is an important issue in the analysis of gene expression microarrays. One type of problem is regional bias, in which one region of a chip shows artifactually high or low...

Exploring the Foundation of Genomics: A Northern Blot Reference set for the Comparative Analysis of Transcript Profiling Technologies (2004)

Danielle Kemmer, Margareta Faxén, Emily Hodges, Jonathan Lim, Elena Herzog, Elsebrit Ljungström, ...

In this paper we aim to create a reference data collection of Northern blot results and demonstrate how such a collection can enable a quantitative comparison of modern expression profiling...

Clonal Mosaic Model for the Synthesis of Mammalian Coat Patterns (1998)

Marcelo Walter, Alain Fournier, Mark Reimers

We introduce the Clonal Mosaic (CM) model for the synthesis of mammalian coat patterns, present its implementation for modeling and display purposes, and give a few examples of generated patterns....

An Integrative Genomic and Epigenomic Approach for the Study of Transcriptional Regulation

Figueroa, Maria E., Reimers, Mark, Thompson, Reid F., Ye, Kenny, Li, Yushan, Selzer, Rebecca R., ...

The molecular heterogeneity of acute leukemias and other tumors constitutes a major obstacle towards understanding disease pathogenesis and developing new targeted-therapies. Aberrant gene regulation...

The LeFE algorithm: embracing the complexity of gene expression in the interpretation of microarray data

Eichler, Gabriel S, Reimers, Mark, Kane, David, Weinstein, John N

The LeFE algorithm has been developed to address the complex, non-linear regulation of gene expression.

Exploring the Foundation of Genomics: A Northern Blot Reference set for the Comparative Analysis of Transcript Profiling Technologies

Kemmer, Danielle, Faxén, Margareta, Hodges, Emily, Lim, Jonathan, Herzog, Elena, Ljungström, Elsebrit, ...

In this paper we aim to create a reference data collection of Northern blot results and demonstrate how such a collection can enable a quantitative comparison of modern expression profiling...