An assessment of the portability of ancestry informative markers between human populations (2009)
Myles, Sean, Stoneking, Mark, Timpson, Nic
Abstract Background Recent work has shown that population stratification can have confounding effects on genetic association studies and statistical methods have been developed to correct for these...
Hughes, David A, Jastroch, Martin, Stoneking, Mark, Klingenspor, Martin
Abstract Background Uncoupling protein 1 (UCP1) is a mitochondrial anion carrier, expressed in brown adipose tissue (BAT) of Eutherians. UCP1 is responsible for uncoupling mitochondrial proton...
Balaresque, Patricia L., Parkin, Emma J., Roewer, Lutz, Carvalho-Silva, Denise R., Mitchell, R. John, ...
This is the author's final draft of the paper published as International Journal of Legal Medicine, 2009, 123 (1), pp. 15-23. The original publication is available at www.springerlink.com. Doi:...
Mona, Stefano, Grunz, Katharina E., Brauer, Silke, Pakendorf, Brigitte, Castrì, Loredana, Sudoyo, Herawati, ...
Eastern Indonesia possesses more linguistic diversity than any other region in Southeast Asia, with both Austronesian (AN) languages that are of East Asian origin, as well as non-Austronesian (NAN)...
Global diversity in the human salivary microbiome (2009)
Nasidze, Ivan, Li, Jing, Quinque, Dominique, Tang, Kun, Stoneking, Mark
The human salivary microbiome may play a role in diseases of the oral cavity and interact with microbiomes from other parts of the human body (in particular, the intestinal tract), but little is...
Worldwide population differentiation at disease-associated SNPs (2008)
Myles, Sean, Davison, Dan, Barrett, Jeffrey, Stoneking, Mark, Timpson, Nic
Abstract Background Recent genome-wide association (GWA) studies have provided compelling evidence of association between genetic variants and common complex diseases. These studies have made use of...
Parallel Selection on TRPV6 in Human Populations (2008)
Hughes, David A., Tang, Kun, Stoneking, Mark, Schöneberg, Torsten, Prenen, Jean, Nilius, Bernd
Genome-wide Analysis Indicates More Asian than Melanesian Ancestry of Polynesians (2008)
Kayser, Manfred, Lao, Oscar, Saar, Kathrin, Brauer, Silke, Wang, Xingyu, Nürnberg, Peter, ...
Mehlotra, Rajeev K., Mattera, Gabriel, Bockarie, Moses J., Maguire, Jason D., Baird, J. Kevin, Sharma, Yagya D., ...
Roewer, Lutz, Willuweit, Sascha, Krüger, Carmen, Nagy, Marion, Rychkov, Sergey, Morozowa, Irina, ...
Fechner, Angela, Quinque, Dominique, Rychkov, Sergey, Morozowa, Irina, Naumova, Oksana, Schneider, Yurij, ...
Worldwide population differentiation at disease-associated SNPs (2008)
Myles, Sean, Davison, Dan, Barrett, Jeffrey, Stoneking, Mark, Timpson, Nic
Balaresque, Patricia, Bowden, Georgina R., Parkin, Emma J., Omran, Gadha A., Heyer, Evelyne, Quintana-Murci, Lluis, ...
Close genetic relationship between semitic-speaking and indo-european-speaking groups in iran (2008)
Nasidze, Ivan, Quinque, Dominique, Rahmani, M., Alemohamad, S. A., Stoneking, Mark
Positive selection in East Asians for an EDAR allele that enhances NF-kappaB activation (2008)
Bryk, Jarosław, Hardouin, Emilie, Pugach, Irina, Hughes, David, Strotmann, Rainer, Stoneking, Mark, ...
Kayser, Manfred, Choi, Ying, Van Oven, Mannis, Mona, Stefano, Brauer, Silke, Trent, Ronald J., ...
The genetic ancestry of Polynesians can be traced to both Asia and Melanesia, which presumably reflects admixture occurring between incoming Austronesians and resident non-Austronesians in Melanesia...
Parallel selection on TRPV6 in human populations (2008)
Tang, Kun, Strotmann, Rainer, Schöneberg, Torsten, Prenen, Jean, ...
We identified and examined a candidate gene for local directional selection in Europeans, TRPV6, and conclude that selection has acted on standing genetic variation at this locus, creating parallel...
A New Approach for Using Genome Scans to Detect Recent Positive Selection in the Human Genome (2007)
Kun Tang, Kevin R. Thornton, Mark Stoneking
Genome-wide scanning for signals of recent positive selection is essential for a comprehensive and systematic understanding of human adaptation. Here, we present a genomic survey of recent local...
DaRe, Jeana T, Mehlotra, Rajeev K, Michon, Pascal, Mueller, Ivo, Reeder, John, Sharma, Yagya D, ...
Abstract Background Polymorphism in the pfcrt gene underlies Plasmodium falciparum chloroquine resistance (CQR), as sensitive strains consistently carry lysine (K), while CQR strains carry threonine...
Identifying genes underlying skin pigmentation differences among human populations (2007)
Myles, Sean, Somel, Mehmet, Tang, Kun, Kelso, Janet, Stoneking, Mark
In search of polymorphic alu insertions with restricted geographic distributions (2007)
Cordaux, Richard, Srikanta, Deepa, Lee, Jungnam, Stoneking, Mark, Batzer, Mark A.
The Gagauz, a Linguistic Enclave, are not a Genetic Isolate (2007)
Nasidze, Ivan, Quinque, Dominique, Udina, Irina, Kunizheva, Svetlana, Stoneking, Mark
Kuch, Melanie, Gröcke, Darren R., Knyf, Martin C., Gilbert, M. Thomas P., Younghusband, Ban, Young, Terry, ...
A New Approach for Using Genome Scans to Detect Recent Positive Selection in the Human Genome (2007)
Rootsi, Siiri, Zhivotovsky, Lev A., Baldovic, Marian, Kayser, Manfred, Kutuev, Ildus A., Khusainova, Rita, ...
Y-chromosomal STR haplotypes in Kalmyk population samples (2007)
Roewer, Lutz, Krüger, Carmen, Willuweit, Sascha, Nagy, Marion, Rodig, Heike, Kokshunova, Lyudmila, ...
A Melanocortin 1 Receptor Allele Suggests Varying Pigmentation Among Neanderthals (2007)
Lalueza-Fox, Carles, Römpler, Holger, Caramelli, David, Stäubert, Claudia, Catalano, Giulio, Hughes, David, ...
Close Genetic Relationship Between Semitic-speaking and Indo-European-speaking Groups in Iran (2007)
Nasidze, Ivan, Quinque, Dominique, Rahmani, M., Alemohamad, S. A., Stoneking, Mark
DaRe, Jeana T., Mehlotra, Rajeev K., Michon, Pascal, Mueller, Ivo, Reeder, John, Sharma, Yagya D., ...
DaRe, Jeana T, Mehlotra, Rajeev K, Michon, Pascal, Mueller, Ivo, Reeder, John, Sharma, Yagya D, ...
BACKGROUND: Polymorphism in the pfcrt gene underlies Plasmodium falciparum chloroquine resistance (CQR), as sensitive strains consistently carry lysine (K), while CQR strains carry threonine (T) at...
Dual origins of the Japanese : common ground for hunter-gatherer and farmer Y chromosomes (2006)
Hammer, M. F., Karafet, H., Park, H., Omoto, K., Harihara, S., Stoneking, Mark, ...
The Gagauz, a linguistic enclave, are not a genetic isolate (2006)
Nasidze, Ivan, Quinque, Dominique, Udina, I., Kunizheva, S., Stoneking, Mark
Concomitant replacement of language and mtDNA in South Caspian populations of Iran (2006)
Nasidze, Ivan, Quinque, Dominique, Rahmani, M., Alemohamad, S. A., Stoneking, Mark
Evaluation of saliva as a source of human DNA for population and association studies (2006)
Quinque, Dominique, Kittler, Ralf, Kayser, Manfred, Stoneking, Mark, Nasidze, Ivan
Kayser, Manfred, Brauer, Silke, Cordaux, Richard, Casto, Amanda, Lao, Oscar, Zhivotovsky, Lev A., ...
Pakendorf, Brigitte, Novgorodov, I. N., Osakovskij, V. L., Danilova, A. P., Protod´jakonov, A.P., Stoneking, Mark
Identifying genes underlying skin pigmentation differences among human populations (2006)
Myles, Sean, Somel, Mehmet, Tang, Kun, Kelso, Janet, Stoneking, Mark
Kayser, Manfred, Brauer, Silke, Cordaux, Richard, Casto, Amanda, Lao, Oscar, Zhivotovsky, Lev A., ...
The human settlement of the Pacific Islands represents one of the most recent major migration events of mankind. Polynesians originated in Asia according to linguistic evidence or in Melanesia...
Kayser, Manfred, Brauer, Silke, Cordaux, Richard, Casto, Amanda, Lao, Oscar, Zhivotovsky, Lev A., ...
The human settlement of the Pacific Islands represents one of the most recent major migration events of mankind. Polynesians originated in Asia according to linguistic evidence or in Melanesia...
Hamilton, Grant S., Stoneking, Mark, Excoffier, Laurent
Human social organization can deeply affect levels of genetic diversity. This fact implies that genetic information can be used to study social structures, which is the basis of ethnogenetics....
Hamilton, Grant S., Stoneking, Mark, Excoffier, Laurent
Human social organization can deeply affect levels of genetic diversity. This fact implies that genetic information can be used to study social structures, which is the basis of ethnogenetics....
Hamilton, Grant S., Stoneking, Mark, Excoffier, Laurent
Human social organization can deeply affect levels of genetic diversity. This fact implies that genetic information can be used to study social structures, which is the basis of ethnogenetics....
Recent Origin and Cultural Reversion of a Hunter–Gatherer Group (2005)
Hiroki Oota, Brigitte Pakendorf, Gunter Weiss, Arndt Von Haeseler, Surin Pookajorn, Wannapa Settheetham-Ishida, ...
Genes, language and culture reveal that the Mlabri reverted from an agricultural to a hunter-gatherer lifestyle, suggesting that hunter-gatherer groups might not always represent the pre-...
Recent Origin and Cultural Reversion of a Hunter–Gatherer Group (2005)
Hiroki Oota, Brigitte Pakendorf, Gunter Weiss, Arndt Von Haeseler, Surin Pookajorn, Wannapa Settheetham-Ishida, ...
Contemporary hunter–gatherer groups are often thought to serve as models of an ancient lifestyle that was typical of human populations prior to the development of agriculture. Patterns of genetic...
Recent Origin and Cultural Reversion of a Hunter–Gatherer Group (2005)
Oota, Hiroki, Pakendorf, Brigitte, Weiss, Gunter, Von Haeseler, Arndt, Pookajorn, Surin, Settheetham-Ishida, Wannapa, ...
Contemporary hunter–gatherer groups are often thought to serve as models of an ancient lifestyle that was typical of human populations prior to the development of agriculture. Patterns of genetic...
Genetic evidence for the Mongolian ancestry of Kalmyks (2005)
Nasidze, Ivan, Quinque, Dominique, Dupanloup, I., Cordaux, Richard, Kokshunova, L., Stoneking, Mark
MtDNA and Y-chromosome variation in Kurdish groups (2005)
Nasidze, Ivan, Quinque, Dominique, Ozturk, M., Bendukidze, N., Stoneking, Mark
In order to investigate the origins and relationships of Kurdish-speaking groups, mtDNA HV1 sequences, eleven Y chromosome bi-allelic markers, and 9 Y-STR loci were analyzed among three Kurdish...
Hamilton, Grant S., Stoneking, Mark, Excoffier, Laurent
Human social organization can deeply affect levels of genetic diversity. This fact implies that genetic information can be used to study social structures, which is the basis of ethnogenetics....
Hamilton, Grant S., Stoneking, Mark, Excoffier, Laurent
Human social organization can deeply affect levels of genetic diversity. This fact implies that genetic information can be used to study social structures, which is the basis of ethnogenetics....
Hamilton, Grant S., Stoneking, Mark, Excoffier, Laurent
Human social organization can deeply affect levels of genetic diversity. This fact implies that genetic information can be used to study social structures, which is the basis of ethnogenetics....
Hamilton, Grant S., Stoneking, Mark, Excoffier, Laurent
Human social organization can deeply affect levels of genetic diversity. This fact implies that genetic information can be used to study social structures, which is the basis of ethnogenetics....
Hamilton, Grant S., Stoneking, Mark, Excoffier, Laurent
Human social organization can deeply affect levels of genetic diversity. This fact implies that genetic information can be used to study social structures, which is the basis of ethnogenetics....
Hamilton, Grant S., Stoneking, Mark, Excoffier, Laurent
Human social organization can deeply affect levels of genetic diversity. This fact implies that genetic information can be used to study social structures, which is the basis of ethnogenetics....
Independent origins of Indian caste and tribal paternal lineages (2004)
Cordaux, Richard, Aunger, R., Bentley, G., Nasidze, Ivan, Sirajuddin, S. M., Stoneking, Mark
Y-STR haplotypes from eight south Indian groups based on five loci (2004)
Cordaux, Richard, Bentley, G., Aunger, R., Sirajuddin, S. M., Stoneking, Mark
Genetic evidence for the demic diffusion of agriculture to India (2004)
Cordaux, Richard, Edwin, D., Vishwanathan, H., Stoneking, Mark
A comprehensive survey of human Y-chromosomal microsatellites (2004)
Kayser, Manfred, Kittler, Ralf, Erler, Axel, Hedman, M., Lee, A. C., Mohyuddin, A., ...
Mitochondrial DNA and Y-chromosome variation in the Caucasus (2004)
Nasidze, Ivan, Ling, E. Y., Quinque, D., Dupanloup, I., Cordaux, Richard, Rychkov, S., ...
Genetic evidence concerning the origins of South and North Ossetians (2004)
Nasidze, Ivan, Quinque, D., Dupanloup, I., Rychkov, S., Naumova, O., Zhukova, O., ...
A Comprehensive Survey of Human Y-Chromosomal Microsatellites (2004)
Kayser, Manfred, Kittler, Ralf, Erler, Axel, Hedman, Minttu, Lee, Andrew C., Mohyuddin, Aisha, ...
This is the version as printed in the American Journal of Human Genetics by the University of Chicago Press. Their website is http://www.journals.uchicago.edu/AJHG/home.html
The Northeast Indian Passageway: A Barrier or Corridor for Human Migrations? (2004)
Cordaux, Richard, Weiss, Gunter, Saha, Nilmani, Stoneking, Mark
The northeast Indian passageway connecting the Indian subcontinent to east/southeast Asia is thought to have been a major corridor for human migrations. Because it is also an important linguistic...
The Northeast Indian Passageway: A Barrier or Corridor for Human Migrations? (2004)
Cordaux, Richard, Weiss, Gunter, Saha, Nilmani, Stoneking, Mark
The northeast Indian passageway connecting the Indian subcontinent to East/Southeast Asia is thought to have been a major corridor for human migrations. Because it is also an important linguistic...
The Northeast Indian Passageway: A Barrier or Corridor for Human Migrations? (2004)
Cordaux, Richard, Weiss, Gunter, Saha, Nilmani, Stoneking, Mark
The northeast Indian passageway connecting the Indian subcontinent to east/southeast Asia is thought to have been a major corridor for human migrations. Because it is also an important linguistic...
Mitochondrial DNA analysis reveals diverse histories of tribal populations of India (2003)
Cordaux, Richard, Saha, N., Bentley, G. R., Aunger, A., Sirajuddin, S. M., Stoneking, Mark
Apparent intra-chromosomal exchange on the human Y chromosome explained by population history (2003)
Kittler, Ralf, Erler, Axel, Brauer, Silke, Stoneking, Mark, Kayser, Manfred
Mitochondrial DNA evidence for admixed origins of central Siberian populations (2003)
Pakendorf, Brigitte, Wiebe, Victor, Tarskaia, L. A., Spitsyn, V. A., Soodyall, H., Rodewald, A., ...
Kayser, Manfred, Brauer, Silke, Sch Dlich, Hiltrud, Prinz, Mechthild, Batzer, Mark A., Zimmerman, Peter A., ...
To investigate geographic structure within U.S. ethnic populations, we analyzed 1705 haplotypes on the basis of 9 short tandem repeat (STR) loci on the Y-chromosome from 9-11 groups each of...
Kayser, Manfred, Brauer, Silke, Stoneking, Mark
As human populations dispersed throughout the world, they were subjected to new selective forces, which must have led to local adaptation via natural selection and hence altered patterns of genetic...
Kayser, Manfred, Brauer, Silke, Stoneking, Mark
As human populations dispersed throughout the world, they were subjected to new selective forces, which must have led to local adaptation via natural selection and hence altered patterns of genetic...
Kayser, Manfred, Brauer, Silke, Schädlich, Hiltrud, Prinz, Mechthild, Batzer, Mark A., Zimmerman, Peter A., ...
To investigate geographic structure within U.S. ethnic populations, we analyzed 1705 haplotypes on the basis of 9 short tandem repeat (STR) loci on the Y-chromosome from 9–11 groups each of...
Kayser, Manfred, Brauer, Silke, Stoneking, Mark
As human populations dispersed throughout the world, they were subjected to new selective forces, which must have led to local adaptation via natural selection and hence altered patterns of genetic...
Kayser, Manfred, Brauer, Silke, Willuweit, S., Schadlich, H., Batzer, M. A., Zawacki, J., ...
We describe here an online Y-chromosomal short tandem repeat haplotype reference database (YHRD) for U.S. populations, which represents 9-locus Y-STR haplotypes for 1705 African-Americans....
Extreme mtDNA homogeneity in continental Asian populations (2002)
Oota, Hiroshi, Kitano, T., Jin, F., Yuasa, I., Wang, L., Ueda, S., ...
Mitochondrial DNA (mtDNA) variation in continental Asia has not been well-studied. Here, we report mtDNA HV1 sequences for 84 Xi'an and 82 Changsha Han Chinese, 89 Honshu Japanese, and 35 Vietnamese....
Y-chromosomal evidence for a strong reduction in male population size of Yakuts (2002)
Pakendorf, Brigitte, Morar, B., Tarskaia, L. A., Kayser, Manfred, Soodyall, H., Rodewald, A., ...
Romualdi, C., Balding, D., Nasidze, Ivan, Risch, G., Robichaux, M., Sherry, S. T., ...
Previous studies have reported that about 85% of human diversity at Short Tandem Repeat (STR) and Restriction Fragment Length Polymorphism (RFLP) autosomal loci is due to differences between...
Kittler, Ralf, Stoneking, Mark, Kayser, Manfred
Several whole genome amplification strategies have been developed to preamplify the entire genome from minimal amounts of DNA for subsequent molecular genetic analysis. However, none of these...
Phylogenetic analysis of the Friedreich ataxia GAA trinucleotide repeat. (2001)
Justice, C. M., Den, Z., Nguyen, S. V., Stoneking, Mark, Deininger, P. L., Batzer, M. A., ...
Independent histories of human Y chromosomes from Melanesia and Australia. (2001)
Kayser, Manfred, Brauer, Silke, Weiss, Gunter, Schiefenhövel, W., Underhill, P. A., Stoneking, Mark
Diversity and heterogeneity in mitochondrial DNA of North American populations. (2001)
Melton, T., Clifford, S., Kayser, Manfred, Nasidze, Ivan, Batzer, M., Stoneking, Mark
Alu insertion polymorphisms and the genetic structure of human populations from the Caucasus. (2001)
Nasidze, Ivan, Risch, G. M., Robichaux, M., Sherry, S. T., Batzer, M. A., Stoneking, Mark
Alu insertion polymorphisms in humans: a review. (2001)
Donnelly, P., Foley, R., Stoneking, Mark, Deininger, P. L., Batzer, M. A.
Mitochondrial DNA sequences in prehistoric human remains from the Alps. (2000)
Di Benedetto, G., Nasidze, Ivan, Stenico, M., Nigro, L., Krings, M., Lanzinger, M., ...
HLA-DQ haplotypes in 15 different populations. (2000)
Kasahara, M., Begovich., A. B., Klitz, W., Steiner, L. L., Grams, S., Suraj-Baker, V., ...
Mitochondrial DNA sequences in prehistoric human remains from the Alps. (2000)
Di Benedetto, G., Nasidze, Ivan, Stenico, M., Nigro, L., Krings, M., Lanzinger, M., ...
Melanesian origin of Polynesian Y chromosomes. (2000)
Kayser, Manfred, Brauer, Silke, Weiss, G., Underhill, P. A., Roewer, L., Schiefenhövel, W., ...
Reading between the LINEs: human genomic variation induced by LINE-1 retrotransposition. (2000)
Sheen, F., Sherry, S. T., Risch, G. M., Robichaux, M., Nasidze, Ivan, Stoneking, Mark, ...
Reading between the LINEs: Human Genomic Variation Induced by LINE-1 Retrotransposition (2000)
Sheen, Fang-miin, Sherry, Stephen T., Risch, Gregory M., Robichaux, Myles, Nasidze, Ivane, Stoneking, Mark, ...
MtDNA Analysis of Nile River Valley Populations: A Genetic Corridor or aBarrier to Migration? (1999)
Krings, Matthias, Salem, Abd-el Halim, Bauer, Karin, Geisert, Helga, Malek, Adel K., Chaix, Louis, ...
Sequential Loss of Two Neighboring Exons of the Tropoelastin Gene During Primate Evolution (1999)
Szabó, Zoltán, Levi-Minzi, Simona A., Christiano, Angela M., Struminger, Carole, Stoneking, Mark, Batzer, Mark A., ...
Mitochondrial mutation rate revisited: hot spots and polymorphism (1998)
Jazin, Elena, Soodyall, Himla, Jalonen, Paula, Lindholm, Eva, Stoneking, Mark, Gyllenstein, Ulf
Polymorphic Alu insertions and the Asian origin of native American populations (1998)
Novick, Gabriele E., Novick, Corina C., Yunis, Juan, Yunis, Emilio, Mayolo, Pamela A., Scheer, W. Douglas, ...
Genetic Structure of the Ancestral Population of Modern Humans (1998)
Zietkiewicz, Ewa, Yotova, Vania, Jarnik, Michal, Korab-Laskowska, Maria, Kidd, Kenneth K., Modiano, David, ...
Response: Alu repeats and human evolution (1997)
Batzer, Mark A., Sherry, Stephen T., Deininger, Prescott L., Stoneking, Mark
Extent of heterogeneity in mitochondrial DNA of sub-Saharan African populations (1997)
Melton, T., Ginther, C., Sensabaugh, G., Soodyall, G., Stoneking, Mark
The founding mitochondrial DNA lineages of Tristan da Cunha Islanders (p 157-166) (1997)
Soodyall, Himla, Jenkis, Trefor, Mukherjee, Arindam, Du Toit, Ernette, Roberts, Derek F., Stoneking, Mark
Neandertal DNA Sequences and the Origin of Modern Humans (1997)
Krings, Matthias, Stone, Anne, Schmitz, Ralf W., Krainitzki, Heike, Stoneking, Mark, Pääbo, Svante
Stoneking, Mark, Fontius, Jennifer J., Clifford, Stephanie L., Soodyall, Himla, Arcot, Santosh S., Saha, Nilmani, ...
Stoneking, Mark, Fontius, Jennifer J., Clifford, Stephanie L., Soodyall, Himla, Arcot, Santosh S., Saha, Nilmani, ...
A Molecular basis for human hypersensitivity of aminoglyscoside antibiotics (1993)
Hutchin, Tim, Haworth, Lan, Higashi, Koichiro, Fischel-Ghodsian, Nathan, Stoneking, Mark, Saha, N., ...
We have investigated the distribution of mitochondrial DNA polymorphisms in a rare maternally transmitted genetic trait that causes hypersensitivity to aminoglycoside antibiotics, In the hope that a...
Vigilant, Linda, Stoneking, Mark, Wilson, Allan C.
Restriction enzyme analysis of 241 human mtDNAs revealed polymorphism in the electrophoretic mobility of a fragment corresponding to part of the ND4 gene. Enzymatic amplification and direct...
Length mutations in human mitochondrial DNA: direct sequencing of enzymatically amplified DNA (1987)
Wrischnik, Lisa A., Higuchi, Russell G., Stoneking, Mark, Erlich, Henry A., Arnheim, Norman, Wilson, Allan C.
A specific segment of mitochondrial DNA from 18 people was examined by two methods of direct DNA sequencing. This segment includes a small noncoding region (V) shown before by restriction analysis to...
Linkage and other relations of the ptc-tasting and kell blood group system loci / (1977)
Typescript.
Patterns of Human Diversity, within and among Continents, Inferred from Biallelic DNA Polymorphisms
Romualdi, Chiara, Balding, David, Nasidze, Ivane S., Risch, Gregory, Robichaux, Myles, Sherry, Stephen T., ...
Previous studies have reported that about 85% of human diversity at Short Tandem Repeat (STR) and Restriction Fragment Length Polymorphism (RFLP) autosomal loci is due to differences between...
Alu Insertion Polymorphisms and Human Evolution: Evidence for a Larger Population Size in Africa
Stoneking, Mark, Fontius, Jennifer J., Clifford, Stephanie L., Soodyall, Himla, Arcot, Santosh S., Saha, Nilmani, ...
Alu insertion polymorphisms (polymorphisms consisting of the presence/absence of an Alu element at a particular chromosomal location) offer several advantages over other nuclear DNA polymorphisms for...
Reading between the LINEs: Human Genomic Variation Induced by LINE-1 Retrotransposition
Sheen, Fang-miin, Sherry, Stephen T., Risch, Gregory M., Robichaux, Myles, Nasidze, Ivane, Stoneking, Mark, ...
The insertion of mobile elements into the genome represents a new class of genetic markers for the study of human evolution. Long interspersed elements (LINEs) have amplified to a copy number of...
Kayser, Manfred, Brauer, Silke, Schädlich, Hiltrud, Prinz, Mechthild, Batzer, Mark A., Zimmerman, Peter A., ...
To investigate geographic structure within U.S. ethnic populations, we analyzed 1705 haplotypes on the basis of 9 short tandem repeat (STR) loci on the Y-chromosome from 9–11 groups each of...
Recent Origin and Cultural Reversion of a Hunter–Gatherer Group
Oota, Hiroki, Pakendorf, Brigitte, Weiss, Gunter, Von Haeseler, Arndt, Pookajorn, Surin, Settheetham-Ishida, Wannapa, ...
Contemporary hunter–gatherer groups are often thought to serve as models of an ancient lifestyle that was typical of human populations prior to the development of agriculture. Patterns of genetic...
Hamilton, Grant, Stoneking, Mark, Excoffier, Laurent
Human social organization can deeply affect levels of genetic diversity. This fact implies that genetic information can be used to study social structures, which is the basis of ethnogenetics....
Independent Histories of Human Y Chromosomes from Melanesia and Australia
Kayser, Manfred, Brauer, Silke, Weiss, Gunter, Schiefenhövel, Wulf, Underhill, Peter A., Stoneking, Mark
To investigate the origins and relationships of Australian and Melanesian populations, 611 males from 18 populations from Australia, Melanesia, and eastern/southeastern Asia were typed for eight...
Hypervariable Sites in the mtDNA Control Region Are Mutational Hotspots
Hypervariable sites in human mtDNA are readily identified in evolutionary studies and are usually assumed to represent mutational hotspots. Recently, an alternative hypothesis was proposed that holds...
May, Bernie, Stoneking, Mark, Wright, James E.
The results of more than 300 pairwise examinations of biochemical loci for joint segregation in brook trout (Salvelinus fontinalis) and in the hybridized genome of lake trout (S. namaycush) x brook...
Helmuth, Rhea, Fildes, Nicola, Blake, Edward, Luce, Michael C., Chimera, J., Madej, Roberta, ...
Allele and genotype frequencies at the HLA-DQα locus have been determined by the use of polymerase chain reaction (PCR) amplification and nonradioactive oligonucleotide probes. The probes define six...
Patterns of Human Diversity, within and among Continents, Inferred from Biallelic DNA Polymorphisms
Romualdi, Chiara, Balding, David, Nasidze, Ivane S., Risch, Gregory, Robichaux, Myles, Sherry, Stephen T., ...
Previous studies have reported that about 85% of human diversity at Short Tandem Repeat (STR) and Restriction Fragment Length Polymorphism (RFLP) autosomal loci is due to differences between...
Alu Insertion Polymorphisms and Human Evolution: Evidence for a Larger Population Size in Africa
Stoneking, Mark, Fontius, Jennifer J., Clifford, Stephanie L., Soodyall, Himla, Arcot, Santosh S., Saha, Nilmani, ...
Alu insertion polymorphisms (polymorphisms consisting of the presence/absence of an Alu element at a particular chromosomal location) offer several advantages over other nuclear DNA polymorphisms for...
Reading between the LINEs: Human Genomic Variation Induced by LINE-1 Retrotransposition
Sheen, Fang-miin, Sherry, Stephen T., Risch, Gregory M., Robichaux, Myles, Nasidze, Ivane, Stoneking, Mark, ...
The insertion of mobile elements into the genome represents a new class of genetic markers for the study of human evolution. Long interspersed elements (LINEs) have amplified to a copy number of...
Reduced Y-Chromosome, but Not Mitochondrial DNA, Diversity in Human Populations from West New Guinea
Kayser, Manfred, Brauer, Silke, Weiss, Gunter, Schiefenhövel, Wulf, Underhill, Peter, Shen, Peidong, ...
To investigate the paternal population history of New Guinea, 183 individuals from 11 regional populations of West New Guinea (WNG) and 131 individuals from Papua New Guinea (PNG) were analyzed at 26...
Kayser, Manfred, Brauer, Silke, Schädlich, Hiltrud, Prinz, Mechthild, Batzer, Mark A., Zimmerman, Peter A., ...
To investigate geographic structure within U.S. ethnic populations, we analyzed 1705 haplotypes on the basis of 9 short tandem repeat (STR) loci on the Y-chromosome from 9–11 groups each of...
Recent Origin and Cultural Reversion of a Hunter–Gatherer Group
Oota, Hiroki, Pakendorf, Brigitte, Weiss, Gunter, Von Haeseler, Arndt, Pookajorn, Surin, Settheetham-Ishida, Wannapa, ...
Contemporary hunter–gatherer groups are often thought to serve as models of an ancient lifestyle that was typical of human populations prior to the development of agriculture. Patterns of genetic...
Hamilton, Grant, Stoneking, Mark, Excoffier, Laurent
Human social organization can deeply affect levels of genetic diversity. This fact implies that genetic information can be used to study social structures, which is the basis of ethnogenetics....
A Comprehensive Survey of Human Y-Chromosomal Microsatellites
Kayser, Manfred, Kittler, Ralf, Erler, Axel, Hedman, Minttu, Lee, Andrew C., Mohyuddin, Aisha, ...
We have screened the nearly complete DNA sequence of the human Y chromosome for microsatellites (short tandem repeats) that meet the criteria of having a repeat-unit size of ⩾3 and a repeat count...
May, Bernie, Stoneking, Mark, Wright, James E.
The results of more than 300 pairwise examinations of biochemical loci for joint segregation in brook trout (Salvelinus fontinalis) and in the hybridized genome of lake trout (S. namaycush) x brook...
Independent Histories of Human Y Chromosomes from Melanesia and Australia
Kayser, Manfred, Brauer, Silke, Weiss, Gunter, Schiefenhövel, Wulf, Underhill, Peter A., Stoneking, Mark
To investigate the origins and relationships of Australian and Melanesian populations, 611 males from 18 populations from Australia, Melanesia, and eastern/southeastern Asia were typed for eight...
Hypervariable Sites in the mtDNA Control Region Are Mutational Hotspots
Hypervariable sites in human mtDNA are readily identified in evolutionary studies and are usually assumed to represent mutational hotspots. Recently, an alternative hypothesis was proposed that holds...
Helmuth, Rhea, Fildes, Nicola, Blake, Edward, Luce, Michael C., Chimera, J., Madej, Roberta, ...
Allele and genotype frequencies at the HLA-DQα locus have been determined by the use of polymerase chain reaction (PCR) amplification and nonradioactive oligonucleotide probes. The probes define six...
A New Approach for Using Genome Scans to Detect Recent Positive Selection in the Human Genome
Tang, Kun, Thornton, Kevin R, Stoneking, Mark
Genome-wide scanning for signals of recent positive selection is essential for a comprehensive and systematic understanding of human adaptation. Here, we present a genomic survey of recent local...
DaRe, Jeana T., Mehlotra, Rajeev K., Michon, Pascal, Mueller, Ivo, Reeder, John, Sharma, Yagya D., ...
Parallel Selection on TRPV6 in Human Populations
Hughes, David A., Tang, Kun, Strotmann, Rainer, Schöneberg, Torsten, Prenen, Jean, Nilius, Bernd, ...
We identified and examined a candidate gene for local directional selection in Europeans, TRPV6, and conclude that selection has acted on standing genetic variation at this locus, creating parallel...
Positive Selection in East Asians for an EDAR Allele that Enhances NF-κB Activation
Bryk, Jarosław, Hardouin, Emilie, Pugach, Irina, Hughes, David, Strotmann, Rainer, Stoneking, Mark, ...
Genome-wide scans for positive selection in humans provide a promising approach to establish links between genetic variants and adaptive phenotypes. From this approach, lists of hundreds of candidate...
Genome-wide Analysis Indicates More Asian than Melanesian Ancestry of Polynesians
Kayser, Manfred, Lao, Oscar, Saar, Kathrin, Brauer, Silke, Wang, Xingyu, Nürnberg, Peter, ...
Analyses of mitochondrial DNA (mtDNA) and nonrecombining Y chromosome (NRY) variation in the same populations are sometimes concordant but sometimes discordant. Perhaps the most dramatic example...
Worldwide population differentiation at disease-associated SNPs
Myles, Sean, Davison, Dan, Barrett, Jeffrey, Stoneking, Mark, Timpson, Nic
Mehlotra, Rajeev K., Mattera, Gabriel, Bockarie, Moses J., Maguire, Jason D., Baird, J. Kevin, Sharma, Yagya D., ...
Mutations in the chloroquine resistance (CQR) transporter gene of Plasmodium falciparum (Pfcrt; chromosome 7) play a key role in CQR, while mutations in the multidrug resistance gene (Pfmdr1;...
Molecular evolution of UCP1 and the evolutionary history of mammalian non-shivering thermogenesis
Hughes, David A, Jastroch, Martin, Stoneking, Mark, Klingenspor, Martin
Positive selection in East Asians for an EDAR allele that enhances NF-kappaB activation
Bryk, Jarosław, Hardouin, Emilie, Pugach, Irina, Hughes, David, Strotmann, Rainer, Stoneking, Mark, ...
Genome-wide scans for positive selection in humans provide a promising approach to establish links between genetic variants and adaptive phenotypes. From this approach, lists of hundreds of candidate...
Global diversity in the human salivary microbiome
Nasidze, Ivan, Li, Jing, Quinque, Dominique, Tang, Kun, Stoneking, Mark
The human salivary microbiome may play a role in diseases of the oral cavity and interact with microbiomes from other parts of the human body (in particular, the intestinal tract), but little is...
Roewer, Lutz, Willuweit, Sascha, Krüger, Carmen, Nagy, Marion, Rychkov, Sergey, Morozowa, Irina, ...
A total of 17 Y-specific STR loci were studied in 12 districts of the European part of Russia aiming to ascertain the amount of substructure required for the construction of a representative regional...