Mark W. Duncan

Quantitative matrix-assisted laser desorption/ionization mass spectrometry (2008)

Duncan, Mark W., Roder, Heinrich, Hunsucker, Stephen W.

This review summarizes the essential characteristics of matrix-assisted laser desorption/ionization (MALDI) time-of-flight mass spectrometry (TOF MS), especially as they relate to its applications in...

Brain Uptake, Pharmacokinetics, and Tissue Distribution in the Rat of Neurotoxic N-Butylbenzenesulfonamide (2007)

Kumar, Ganesh, Smith, Quentin R., Hokari, Mitsuhiko, Parepally, Jagan, Duncan, Mark W.

Mass Spectrometry to Classify Non-Small-Cell Lung Cancer Patients for Clinical Outcome After Treatment With Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors: A Multicohort Cross-Institutional Study (2007)

Taguchi, Fumiko, Solomon, Benjamin, Gregorc, Vanesa, Roder, Heinrich, Gray, Robert, Kasahara, Kazuo, ...

Background Some but not all patients with non–small-cell lung cancer (NSCLC) respond to treatment with epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs). We developed and...

Brain Uptake, Pharmacokinetics, and Tissue Distribution in the Rat of Neurotoxic N-Butylbenzenesulfonamide (2007)

Kumar, Ganesh, Smith, Quentin R., Hokari, Mitsuhiko, Parepally, Jagan, Duncan, Mark W.

The pharmacokinetics, cerebrovascular permeability, and tissue distribution of the neurotoxic plasticizer N-butylbenzenesulfonamide (NBBS) were determined in rats. A stable isotope–labeled form...

Brain uptake, Pharmacokinetics and Tissue Distribution in the Rat of Neurotoxic N-butylbenzenesulfonamide (2007)

Kumar, Ganesh, Smith, Quentin R., Hokari, Mitsuhiko, Parepally, Jagan, Duncan, Mark W.

The pharmacokinetics, cerebrovascular permeability and tissue distribution of the neurotoxic plasticiser N-butylbenzenesulfonamide (NBBS), were determined in rats. A stable isotope labeled form...

Proteomic analysis of a neoplastic mouse lung epithelial cell line whose tumorigenicity has been abrogated by transfection with the gap junction structural gene for connexin 43, Gja1 (2003)

Peebles, Katherine A., Duncan, Mark W., Ruch, Randall J., Malkinson, Alvin M.

In order to examine how tumorigenicity is abrogated by gap junctional intercellular communication (GJIC), protein expression was analyzed in four related mouse lung epithelial cell lines that vary in...

γ-Tocopherol traps mutagenic electrophiles such as NOx and complements α-tocopherol: Physiological implications

Christen, Stephan, Woodall, Alan A., Shigenaga, Mark K., Southwell-Keely, Peter T., Duncan, Mark W., Ames, Bruce N.

Peroxynitrite, a powerful mutagenic oxidant and nitrating species, is formed by the near diffusion-limited reaction of ·NO and O2⨪ during activation of phagocytes. Chronic inflammation induced by...

γ-Tocopherol traps mutagenic electrophiles such as NOx and complements α-tocopherol: Physiological implications

Christen, Stephan, Woodall, Alan A., Shigenaga, Mark K., Southwell-Keely, Peter T., Duncan, Mark W., Ames, Bruce N.

Peroxynitrite, a powerful mutagenic oxidant and nitrating species, is formed by the near diffusion-limited reaction of ·NO and O2⨪ during activation of phagocytes. Chronic inflammation induced by...

Quantitative matrix-assisted laser desorption/ionization mass spectrometry

Duncan, Mark W., Roder, Heinrich, Hunsucker, Stephen W.

This review summarizes the essential characteristics of matrix-assisted laser desorption/ionization (MALDI) time-of-flight mass spectrometry (TOF MS), especially as they relate to its applications in...