Markus Schueler

Prediction of cardiac transcription networks based on molecular data and complex clinical phenotypes (2008)

Toenjes, Martje, Schueler, Markus, Hammer, Stefanie, Pape, Utz J., Fischer, Jenny J., Felix Berger, Felix, ...

We present an integrative approach combining sophisticated techniques to construct cardiac gene regulatory networks based on correlated gene expression and optimized prediction of transcription...

Combinatorial effects of four histone modifications in transcription and differentiation (2008)

Fischer, Jenny J., Toedling, Joern, Krueger, Tammo, Schueler, Markus, Huber, Wolfgang, Sperling, Silke

Nucleosomes are involved in DNA compaction and transcriptional regulation. Yet it is unclear whether histone modification marks are primary or secondary to transcription and whether they interact to...

Genomic organization of transcriptomes in mammals: coregulation and cofunctionality (2007)

Purmann, Antje, Toedling, Joern, Schueler, Markus, Carninci, Piero, Lehrach, Hans, Hayashizaki, Yoshihide, ...

In studies of their transcriptional activity, genomes have shown a high order of organization. We assessed the question of how genomically neighboring genes are transcriptionally coupled across...