Zhang, Bo, Moses, Marsha A, Tsang, Paul CW
Abstract The matrix metalloproteinases (MMPs) and their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs), may mediate the dramatic structural and functional changes in the...
Troponin I is present in human cartilage and inhibits angiogenesis
Moses, Marsha A., Wiederschain, Dmitri, Wu, Inmin, Fernandez, Cecilia A., Ghazizadeh, Vahid, Lane, William S., ...
Cartilage is an avascular and relatively tumor-resistant tissue. Work from a number of laboratories, including our own, has demonstrated that cartilage is an enriched source of endogenous inhibitors...
Matrix metalloproteinase-2 is required for the switch to the angiogenic phenotype in a tumor model
Fang, Jianmin, Shing, Yuen, Wiederschain, Dmitri, Yan, Li, Butterfield, Catherine, Jackson, Geraldine, ...
Among the earliest and most important stages during tumorigenesis is the activation of the angiogenic process, an event that is termed the “switch to the angiogenic phenotype.” We have developed...
PPARγ ligands inhibit primary tumor growth and metastasis by inhibiting angiogenesis
Panigrahy, Dipak, Singer, Samuel, Shen, Lucy Q., Butterfield, Catherine E., Freedman, Deborah A., Chen, Emy J., ...
Several drugs approved for a variety of indications have been shown to exhibit antiangiogenic effects. Our study focuses on the PPARγ ligand rosiglitazone, a compound widely used in the treatment of...
Zhang, Bo, Moses, Marsha A, Tsang, Paul CW
The matrix metalloproteinases (MMPs) and their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs), may mediate the dramatic structural and functional changes in the corpus luteum...
Dose-dependent response of FGF-2 for lymphangiogenesis
Chang, Lynn K., Garcia-Cardeña, Guillermo, Farnebo, Filip, Fannon, Michael, Chen, Emy J., Butterfield, Catherine, ...
Spatio-temporal studies on the growth of capillary blood vessels and capillary lymphatic vessels in tissue remodeling have suggested that lymphangiogenesis is angiogenesis-dependent. We revisited...
Troponin I is present in human cartilage and inhibits angiogenesis
Moses, Marsha A., Wiederschain, Dmitri, Wu, Inmin, Fernandez, Cecilia A., Ghazizadeh, Vahid, Lane, William S., ...
Cartilage is an avascular and relatively tumor-resistant tissue. Work from a number of laboratories, including our own, has demonstrated that cartilage is an enriched source of endogenous inhibitors...
Matrix metalloproteinase-2 is required for the switch to the angiogenic phenotype in a tumor model
Fang, Jianmin, Shing, Yuen, Wiederschain, Dmitri, Yan, Li, Butterfield, Catherine, Jackson, Geraldine, ...
Among the earliest and most important stages during tumorigenesis is the activation of the angiogenic process, an event that is termed the “switch to the angiogenic phenotype.” We have developed...
PPARγ ligands inhibit primary tumor growth and metastasis by inhibiting angiogenesis
Panigrahy, Dipak, Singer, Samuel, Shen, Lucy Q., Butterfield, Catherine E., Freedman, Deborah A., Chen, Emy J., ...
Several drugs approved for a variety of indications have been shown to exhibit antiangiogenic effects. Our study focuses on the PPARγ ligand rosiglitazone, a compound widely used in the treatment of...
Zhang, Bo, Moses, Marsha A, Tsang, Paul CW
The matrix metalloproteinases (MMPs) and their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs), may mediate the dramatic structural and functional changes in the corpus luteum...
Dose-dependent response of FGF-2 for lymphangiogenesis
Chang, Lynn K., Garcia-Cardeña, Guillermo, Farnebo, Filip, Fannon, Michael, Chen, Emy J., Butterfield, Catherine, ...
Spatio-temporal studies on the growth of capillary blood vessels and capillary lymphatic vessels in tissue remodeling have suggested that lymphangiogenesis is angiogenesis-dependent. We revisited...
LaMontagne Jr., Kenneth R., Moses, Marsha A., Wiederschain, Dmitri, Mahajan, Sudipta, Holden, Jeannine, Ghazizadeh, Hamid, ...
Activated ras causes increased activity of several signal transduction systems, including the mitogen-activated protein kinase kinase (MAPKK) pathway and the phosphoinositol-3-kinase (PI-3-K)...
Bone morphogenetic protein 1 processes prolactin to a 17-kDa antiangiogenic factor
Ge, Gaoxiang, Fernández, Cecilia A., Moses, Marsha A., Greenspan, Daniel S.
In addition to classical expression patterns in pituitary and placenta and functions in growth and reproduction, members of the small family of hormones that includes prolactin (PRL), growth hormone...
Lipocalin 2 promotes breast cancer progression
Yang, Jiang, Bielenberg, Diane R., Rodig, Scott J., Doiron, Robert, Clifton, Matthew C., Kung, Andrew L., ...
Here, we report that lipocalin 2 (Lcn2) promotes breast cancer progression, and we identify the mechanisms underlying this function. We first found that Lcn2 levels were consistently associated with...