Klumpp, Jochen, Dorscht, Julia, Lurz, Rudi, Bielmann, Regula, Wieland, Matthias, Zimmer, Markus, ...
Only little information on a particular class of myoviruses, the SPO1-like bacteriophages infecting low-G+C-content, gram-positive host bacteria (Firmicutes), is available. We present the genome...
Bacteriophage Endolysin, Martin J. Loessner, Anette Schneider, Siegfried Scherer
A method for the rapid lysis of Listeria cells, employing a recombinant Listeria bacteriophage A118 lytic enzyme (PLY118), is described. The procedure can be used with all listerial species. It...
Gaeng, Susanne, Scherer, Siegfried, Neve, Horst, Loessner, Martin J.
Bacteriophage lysins (Ply), or endolysins, are phage-encoded cell wall lytic enzymes which are synthesized late during virus multiplication and mediate the release of progeny virions. Bacteriophages...
Maier, Simon K., Scherer, Siegfried, Loessner, Martin J.
We investigated the cellular mechanisms that led to growth inhibition, morphological changes, and lysis of Bacillus cereus WSBC 10030 when it was challenged with a long-chain polyphosphate (polyP)....
Loessner, Martin J., Gaeng, Susanne, Scherer, Siegfried
We have cloned, sequenced, and characterized the genes encoding the lytic system of the unique Staphylococcus aureus phage 187. The endolysin gene ply187 encodes a large cell wall-lytic enzyme (71.6...
Zimmer, Markus, Vukov, Naťasa, Scherer, Siegfried, Loessner, Martin J.
Clostridium perfringens commonly occurs in food and feed, can produce an enterotoxin frequently implicated in food-borne disease, and has a substantial negative impact on the poultry industry. As a...
Lauer, Peter, Chow, Man Yin Nora, Loessner, Martin J., Portnoy, Daniel A., Calendar, Richard
Two site-specific shuttle integration vectors were developed with two different chromosomal bacteriophage integration sites to facilitate strain construction in Listeria monocytogenes. The first...
Zimmer, Markus, Scherer, Siegfried, Loessner, Martin J.
Two temperate viruses, φ3626 and φ8533, have been isolated from lysogenic Clostridium perfringens strains. Phage φ3626 was chosen for detailed analysis and was inspected by electron microscopy,...
Cytolysin-dependent delay of vacuole maturation in macrophages infected with Listeria monocytogenes
Henry, Rebecca, Shaughnessy, Lee, Loessner, Martin J., Alberti-Segui, Christine, Higgins, Darren E., Swanson, Joel A.
The bacterial pathogen Listeria monocytogenes (Lm) evades the antimicrobial mechanisms of macrophages by escaping from vacuoles to the cytosol, through the action of the cytolysin listeriolysin O...
Gaeng, Susanne, Scherer, Siegfried, Neve, Horst, Loessner, Martin J.
Bacteriophage lysins (Ply), or endolysins, are phage-encoded cell wall lytic enzymes which are synthesized late during virus multiplication and mediate the release of progeny virions. Bacteriophages...
Maier, Simon K., Scherer, Siegfried, Loessner, Martin J.
We investigated the cellular mechanisms that led to growth inhibition, morphological changes, and lysis of Bacillus cereus WSBC 10030 when it was challenged with a long-chain polyphosphate (polyP)....
Loessner, Martin J., Gaeng, Susanne, Scherer, Siegfried
We have cloned, sequenced, and characterized the genes encoding the lytic system of the unique Staphylococcus aureus phage 187. The endolysin gene ply187 encodes a large cell wall-lytic enzyme (71.6...
Zimmer, Markus, Vukov, Naťasa, Scherer, Siegfried, Loessner, Martin J.
Clostridium perfringens commonly occurs in food and feed, can produce an enterotoxin frequently implicated in food-borne disease, and has a substantial negative impact on the poultry industry. As a...
Lauer, Peter, Chow, Man Yin Nora, Loessner, Martin J., Portnoy, Daniel A., Calendar, Richard
Two site-specific shuttle integration vectors were developed with two different chromosomal bacteriophage integration sites to facilitate strain construction in Listeria monocytogenes. The first...
Zimmer, Markus, Scherer, Siegfried, Loessner, Martin J.
Two temperate viruses, φ3626 and φ8533, have been isolated from lysogenic Clostridium perfringens strains. Phage φ3626 was chosen for detailed analysis and was inspected by electron microscopy,...
Kretzer, Jan W., Lehmann, Rainer, Schmelcher, Mathias, Banz, Manuel, Kim, Kwang-Pyo, Korn, Corinna, ...
Immobilization and magnetic separation for specific enrichment of microbial cells, such as the pathogen Listeria monocytogenes, depends on the availability of suitable affinity molecules. We report...
Kim, Kwang-Pyo, Loessner, Martin J.
Enterobacter sakazakii is an opportunistic pathogen that causes systemic bacteremia and meningitis with high mortality, and powdered infant formula is a frequent source of this bacterium. However,...
Klumpp, Jochen, Dorscht, Julia, Lurz, Rudi, Bielmann, Regula, Wieland, Matthias, Zimmer, Markus, ...
Only little information on a particular class of myoviruses, the SPO1-like bacteriophages infecting low-G+C-content, gram-positive host bacteria (Firmicutes), is available. We present the genome...
Virulent Bacteriophage for Efficient Biocontrol of Listeria monocytogenes in Ready-To-Eat Foods▿
Guenther, Susanne, Huwyler, Dominique, Richard, Simon, Loessner, Martin J.
Food-borne Listeria monocytogenes is a serious threat to human health, and new strategies to combat this opportunistic pathogen in foods are needed. Bacteriophages are natural enemies of bacteria and...
Schmid, Barbara, Klumpp, Jochen, Raimann, Eveline, Loessner, Martin J., Stephan, Roger, Tasara, Taurai
The gram-positive bacterium Listeria monocytogenes is a food-borne pathogen of both public health and food safety significance. It possesses three small, highly homologous protein members of the cold...
Antimicrobial Properties of a Novel Silver-Silica Nanocomposite Material▿
Egger, Salome, Lehmann, Rainer P., Height, Murray J., Loessner, Martin J., Schuppler, Markus
Nanotechnology enables development and production of novel silver-based composite materials. We used in vitro tests to demonstrate the antimicrobial activity of a silver-silica nanocomposite compared...