Martin Lechmann

Genetic Immunization of Wild-Type and Hepatitis C Virus Transgenic Mice Reveals a Hierarchy of Cellular Immune Response and Tolerance Induction against Hepatitis C Virus Structural Proteins

Satoi, Jujin, Murata, Kazumoto, Lechmann, Martin, Manickan, Elanchezhiyan, Zhang, Zhensheng, Wedemeyer, Heiner, ...

To study the effect of genetic immunization on transgenic expression of hepatitis C virus (HCV) proteins, we evaluated the immunological response of HCV transgenic mice to HCV expression plasmids....

Immunization with hepatitis C virus-like particles protects mice from recombinant hepatitis C virus-vaccinia infection

Murata, Kazumoto, Lechmann, Martin, Qiao, Ming, Gunji, Toshiaki, Alter, Harvey J., Liang, T. Jake

We have recently demonstrated that immunization with hepatitis C virus-like particles (HCV-LPs) generated in insect cells can elicit both humoral and cellular immune responses in BALB/c mice. Here,...

Genetic Immunization of Wild-Type and Hepatitis C Virus Transgenic Mice Reveals a Hierarchy of Cellular Immune Response and Tolerance Induction against Hepatitis C Virus Structural Proteins

Satoi, Jujin, Murata, Kazumoto, Lechmann, Martin, Manickan, Elanchezhiyan, Zhang, Zhensheng, Wedemeyer, Heiner, ...

To study the effect of genetic immunization on transgenic expression of hepatitis C virus (HCV) proteins, we evaluated the immunological response of HCV transgenic mice to HCV expression plasmids....

Immunization with hepatitis C virus-like particles protects mice from recombinant hepatitis C virus-vaccinia infection

Murata, Kazumoto, Lechmann, Martin, Qiao, Ming, Gunji, Toshiaki, Alter, Harvey J., Liang, T. Jake

We have recently demonstrated that immunization with hepatitis C virus-like particles (HCV-LPs) generated in insect cells can elicit both humoral and cellular immune responses in BALB/c mice. Here,...