Soiffer, Robert, Lynch, Thomas, Mihm, Martin, Jung, Ken, Rhuda, Catherine, Schmollinger, Jan C., ...
We conducted a Phase I clinical trial investigating the biologic activity of vaccination with irradiated autologous melanoma cells engineered to secrete human granulocyte–macrophage...
ATP6S1 elicits potent humoral responses associated with immune-mediated tumor destruction
Hodi, F. Stephen, Schmollinger, Jan C., Soiffer, Robert J., Salgia, Ravi, Lynch, Thomas, Ritz, Jerome, ...
An important goal of cancer immunology is the identification of antigens associated with tumor destruction. Vaccination with irradiated tumor cells engineered to secrete granulocyte/macrophage...
Melanoma inhibitor of apoptosis protein (ML-IAP) is a target for immune-mediated tumor destruction
Schmollinger, Jan C., Vonderheide, Robert H., Hoar, Kara M., Maecker, Britta, Schultze, Joachim L., Hodi, F. Stephen, ...
The identification of antigens associated with tumor destruction is a major goal of cancer immunology. Vaccination with irradiated tumor cells engineered to secrete granulocyte–macrophage colony...
Soiffer, Robert, Lynch, Thomas, Mihm, Martin, Jung, Ken, Rhuda, Catherine, Schmollinger, Jan C., ...
We conducted a Phase I clinical trial investigating the biologic activity of vaccination with irradiated autologous melanoma cells engineered to secrete human granulocyte–macrophage...
ATP6S1 elicits potent humoral responses associated with immune-mediated tumor destruction
Hodi, F. Stephen, Schmollinger, Jan C., Soiffer, Robert J., Salgia, Ravi, Lynch, Thomas, Ritz, Jerome, ...
An important goal of cancer immunology is the identification of antigens associated with tumor destruction. Vaccination with irradiated tumor cells engineered to secrete granulocyte/macrophage...
Melanoma inhibitor of apoptosis protein (ML-IAP) is a target for immune-mediated tumor destruction
Schmollinger, Jan C., Vonderheide, Robert H., Hoar, Kara M., Maecker, Britta, Schultze, Joachim L., Hodi, F. Stephen, ...
The identification of antigens associated with tumor destruction is a major goal of cancer immunology. Vaccination with irradiated tumor cells engineered to secrete granulocyte–macrophage colony...
King, Roy, Weilbaecher, Katherine N., McGill, Gaël, Cooley, Edward, Mihm, Martin, Fisher, David E.
Malignant melanomas do not uniformly retain expression of melanocytic gene products—an observation associated with diagnostic dilemmas. Microphthalmia transcription factor (Mitf) is a melanocytic...
Jinushi, Masahisa, Nakazaki, Yukoh, Dougan, Michael, Carrasco, Daniel R., Mihm, Martin, Dranoff, Glenn
Granulocyte-macrophage colony-stimulating factor (GM-CSF) enhances protection against tumors and infections, but GM-CSF–deficient mice develop inflammatory disease. Here we show that GM-CSF is...
Deficiencies of GM-CSF and Interferon γ Link Inflammation and Cancer
Enzler, Thomas, Gillessen, Silke, Manis, John P., Ferguson, David, Fleming, James, Alt, Frederick W., ...
Chronic inflammation contributes to carcinogenesis, but the underlying mechanisms are poorly understood. We report that aged granulocyte-macrophage colony stimulating factor (GM-CSF)-deficient mice...
Enzler, Thomas, Gillessen, Silke, Dougan, Michael, Allison, James P., Neuberg, Donna, Oble, Darryl A., ...
The pathogenesis of type 1 diabetes (T1D) involves the immune-mediated destruction of insulin-producing β cells in the pancreatic islets of Langerhans. Genetic analysis of families with a high...