Martina I. Lefterova

PPAR{gamma} and C/EBP factors orchestrate adipocyte biology via adjacent binding on a genome-wide scale (2008)

Lefterova, Martina I., Zhang, Yong, Steger, David J., Schupp, Michael, Schug, Jonathan, Cristancho, Ana, ...

Peroxisome proliferator-activated receptor γ(PPARγ), a nuclear receptor and the target of anti-diabetic thiazolinedione drugs, is known as the master regulator of adipocyte biology. Although it...

Absence of bacterially induced RELMβ reduces injury in the dextran sodium sulfate model of colitis

McVay, Laila D., Keilbaugh, Sue A., Wong, Tracie M.H., Kierstein, Sonja, Shin, Marcus E., Lehrke, Michael, ...

Although inflammatory bowel disease (IBD) is the result of a dysregulated immune response to commensal gut bacteria in genetically predisposed individuals, the mechanism(s) by which bacteria lead to...

Absence of bacterially induced RELMβ reduces injury in the dextran sodium sulfate model of colitis

McVay, Laila D., Keilbaugh, Sue A., Wong, Tracie M.H., Kierstein, Sonja, Shin, Marcus E., Lehrke, Michael, ...

Although inflammatory bowel disease (IBD) is the result of a dysregulated immune response to commensal gut bacteria in genetically predisposed individuals, the mechanism(s) by which bacteria lead to...

DOT1L/KMT4 Recruitment and H3K79 Methylation Are Ubiquitously Coupled with Gene Transcription in Mammalian Cells▿

Steger, David J., Lefterova, Martina I., Ying, Lei, Stonestrom, Aaron J., Schupp, Michael, Zhuo, David, ...

The histone H3 lysine 79 methyltransferase DOT1L/KMT4 can promote an oncogenic pattern of gene expression through binding with several MLL fusion partners found in acute leukemia. However, the normal...

PPARγ and C/EBP factors orchestrate adipocyte biology via adjacent binding on a genome-wide scale

Lefterova, Martina I., Zhang, Yong, Steger, David J., Schupp, Michael, Schug, Jonathan, Cristancho, Ana, ...

Peroxisome proliferator-activated receptor γ(PPARγ), a nuclear receptor and the target of anti-diabetic thiazolinedione drugs, is known as the master regulator of adipocyte biology. Although it...

Retinol saturase promotes adipogenesis and is downregulated in obesity

Schupp, Michael, Lefterova, Martina I., Janke, Jürgen, Leitner, Kirstin, Cristancho, Ana G., Mullican, Shannon E., ...

Adipocyte differentiation is controlled by many transcription factors, but few known downstream targets of these factors are necessary for adipogenesis. Here we report that retinol saturase (RetSat),...