Martine Guiraud

CD2 and TCR synergize for the activation of phospholipase C{gamma}1/calcium pathway at the immunological synapse (2007)

Espagnolle, Nicolas, Depoil, David, Zaru, Rossana, Demeur, Cecile, Champagne, Eric, Guiraud, Martine, ...

Upon conjugation with cognate antigen-presenting cells (APCs), T lymphocytes undergo a sustained [Ca2+]i increase resulting from the engagement of TCR and of accessory molecules with ligands...

CD2 and TCR synergize for the activation of phospholipase C{gamma}1/calcium pathway at the immunological synapse (2007)

Espagnolle, Nicolas, Depoil, David, Zaru, Rossana, Demeur, Cecile, Champagne, Eric, Guiraud, Martine, ...

Upon conjugation with cognate antigen-presenting cells (APCs), T lymphocytes undergo a sustained [Ca2+]i increase resulting from the engagement of TCR and of accessory molecules with ligands...

CD2 and TCR synergize for the activation of phospholipase C{gamma}1/calcium pathway at the immunological synapse (2007)

Espagnolle, Nicolas, Depoil, David, Zaru, Rossana, Demeur, Cecile, Champagne, Eric, Guiraud, Martine, ...

Upon conjugation with cognate antigen-presenting cells (APCs), T lymphocytes undergo a sustained [Ca2+]i increase resulting from the engagement of TCR and of accessory molecules with ligands...

Tumor recognition following Vgamma9Vdelta2 T cell receptor interactions with a surface F1-ATPase-related structure and apolipoprotein A-I. (2005)

Scotet, Emmanuel, Martinez, Laurent, Grant, Ethan, Barbaras, Ronald, Jenö, Paul, Guiraud, Martine, ...

Vgamma9Vdelta2 T lymphocytes, a major gammadelta T lymphocyte subset in humans, display cytolytic activity against various tumor cells upon recognition of yet uncharacterized structures. Here, we...

Tumor recognition following Vgamma9Vdelta2 T cell receptor interactions with a surface F1-ATPase-related structure and apolipoprotein A-I. (2005)

Scotet, Emmanuel, Martinez, Laurent, Grant, Ethan, Barbaras, Ronald, Jenö, Paul, Guiraud, Martine, ...

Vgamma9Vdelta2 T lymphocytes, a major gammadelta T lymphocyte subset in humans, display cytolytic activity against various tumor cells upon recognition of yet uncharacterized structures. Here, we...

Tumor recognition following Vgamma9Vdelta2 T cell receptor interactions with a surface F1-ATPase-related structure and apolipoprotein A-I. (2005)

Scotet, Emmanuel, Martinez, Laurent, Grant, Ethan, Barbaras, Ronald, Jenö, Paul, Guiraud, Martine, ...

Vgamma9Vdelta2 T lymphocytes, a major gammadelta T lymphocyte subset in humans, display cytolytic activity against various tumor cells upon recognition of yet uncharacterized structures. Here, we...

Lytic versus stimulatory synapse in cytotoxic T lymphocyte/target cell interaction: Manifestation of a dual activation threshold

Faroudi, Mustapha, Utzny, Clemens, Salio, Mariolina, Cerundolo, Vincenzo, Guiraud, Martine, Müller, Sabina, ...

Activation of biological functions in T lymphocytes is determined by the molecular dynamics occurring at the T cell/opposing cell interface. In the present study, a central question of cytotoxic T...

Lytic versus stimulatory synapse in cytotoxic T lymphocyte/target cell interaction: Manifestation of a dual activation threshold

Faroudi, Mustapha, Utzny, Clemens, Salio, Mariolina, Cerundolo, Vincenzo, Guiraud, Martine, Müller, Sabina, ...

Activation of biological functions in T lymphocytes is determined by the molecular dynamics occurring at the T cell/opposing cell interface. In the present study, a central question of cytotoxic T...

Human regulatory T cells inhibit polarization of T helper cells toward antigen-presenting cells via a TGF-β-dependent mechanism

Esquerré, Michael, Tauzin, Baptiste, Guiraud, Martine, Müller, Sabina, Saoudi, Abdelhadi, Valitutti, Salvatore

The molecular mechanisms used by regulatory T cells (Treg) to inhibit the effector phase of adaptive immune responses are still elusive. In the present work, we investigated the possibility that Treg...