Masaaki Miyazawa

Peptide-induced immune protection of CD8+ T cell-deficient mice against Friend retrovirus-induced disease (2006)

Kawabata, Hiroyuki, Niwa, Atsuko, Tsuji-Kawahara, Sachiyo, Uenishi, Hirohide, Iwanami, Norimasa, Matsukuma, Hideaki, ...

CD8+ CTLs and virus-neutralizing antibodies have been associated with spontaneous and vaccine-induced immune control of retroviral infections. We previously showed that a single immunization...

Peptide-induced immune protection of CD8+ T cell-deficient mice against Friend retrovirus-induced disease (2005)

Kawabata, Hiroyuki, Niwa, Atsuko, Tsuji-Kawahara, Sachiyo, Uenishi, Hirohide, Iwanami, Norimasa, Matsukuma, Hideaki, ...

CD8+ CTLs and virus-neutralizing antibodies have been associated with spontaneous and vaccine-induced immune control of retroviral infections. We previously showed that a single immunization with an...

Establishment of Monoclonal Anti-Retroviral gp70 Autoantibodies from MRL/lpr Lupus Mice and Induction of Glomerular gp70 Deposition and Pathology by Transfer into Non-Autoimmune Mice

Tabata, Nobutada, Miyazawa, Masaaki, Fujisawa, Ryuichi, Takei, Yumiko A., Abe, Hiroyuki, Hashimoto, Keiji

Several strains of mice, including MRL/MpJ mice homozygous for the Fas mutant lpr gene (MRL/lpr mice), F1 hybrids of New Zealand Black and New Zealand White mice, and BXSB/MpJ mice carrying a...

Role of Natural Killer Cells in Resistance against Friend Retrovirus-Induced Leukemia

Iwanami, Norimasa, Niwa, Atsuko, Yasutomi, Yasuhiro, Tabata, Nobutada, Miyazawa, Masaaki

We have previously shown that immunization with a synthetic peptide that contains a single CD4+ T-cell epitope protects mice against immunosuppressive Friend retrovirus infection. Cells producing...

Identification of a Protective CD4+ T-Cell Epitope in p15gag of Friend Murine Leukemia Virus and Role of the MA Protein Targeting the Plasma Membrane in Immunogenicity

Sugahara, Daisuke, Tsuji-Kawahara, Sachiyo, Miyazawa, Masaaki

Recent studies have demonstrated an essential role of Gag-specific CD4+ T-cell responses for viral control in individuals infected with human immunodeficiency virus type 1. However, little is known...

Influence of Glycosylation on the Efficacy of an Env-Based Vaccine against Simian Immunodeficiency Virus SIVmac239 in a Macaque AIDS Model

Mori, Kazuyasu, Sugimoto, Chie, Ohgimoto, Shinji, Nakayama, Emi E., Shioda, Tatsuo, Kusagawa, Shigeru, ...

The envelope glycoprotein (Env) of human immunodeficiency viruses (HIVs) and simian immunodeficiency viruses (SIVs) is heavily glycosylated, and this feature has been speculated to be a reason for...

Establishment of Monoclonal Anti-Retroviral gp70 Autoantibodies from MRL/lpr Lupus Mice and Induction of Glomerular gp70 Deposition and Pathology by Transfer into Non-Autoimmune Mice

Tabata, Nobutada, Miyazawa, Masaaki, Fujisawa, Ryuichi, Takei, Yumiko A., Abe, Hiroyuki, Hashimoto, Keiji

Several strains of mice, including MRL/MpJ mice homozygous for the Fas mutant lpr gene (MRL/lpr mice), F1 hybrids of New Zealand Black and New Zealand White mice, and BXSB/MpJ mice carrying a...

Role of Natural Killer Cells in Resistance against Friend Retrovirus-Induced Leukemia

Iwanami, Norimasa, Niwa, Atsuko, Yasutomi, Yasuhiro, Tabata, Nobutada, Miyazawa, Masaaki

We have previously shown that immunization with a synthetic peptide that contains a single CD4+ T-cell epitope protects mice against immunosuppressive Friend retrovirus infection. Cells producing...

Identification of a Protective CD4+ T-Cell Epitope in p15gag of Friend Murine Leukemia Virus and Role of the MA Protein Targeting the Plasma Membrane in Immunogenicity

Sugahara, Daisuke, Tsuji-Kawahara, Sachiyo, Miyazawa, Masaaki

Recent studies have demonstrated an essential role of Gag-specific CD4+ T-cell responses for viral control in individuals infected with human immunodeficiency virus type 1. However, little is known...

Influence of Glycosylation on the Efficacy of an Env-Based Vaccine against Simian Immunodeficiency Virus SIVmac239 in a Macaque AIDS Model

Mori, Kazuyasu, Sugimoto, Chie, Ohgimoto, Shinji, Nakayama, Emi E., Shioda, Tatsuo, Kusagawa, Shigeru, ...

The envelope glycoprotein (Env) of human immunodeficiency viruses (HIVs) and simian immunodeficiency viruses (SIVs) is heavily glycosylated, and this feature has been speculated to be a reason for...

Cytotoxic T Lymphocyte–based Control of Simian Immunodeficiency Virus Replication in a Preclinical AIDS Vaccine Trial

Matano, Tetsuro, Kobayashi, Masahiro, Igarashi, Hiroko, Takeda, Akiko, Nakamura, Hiromi, Kano, Munehide, ...

Recently, encouraging AIDS vaccine trials in macaques have implicated cytotoxic T lymphocytes (CTLs) in the control of the simian human immunodeficiency virus SHIV89.6P that induces acute CD4+ T cell...

Mouse APOBEC3 Restricts Friend Leukemia Virus Infection and Pathogenesis In Vivo▿

Takeda, Eri, Tsuji-Kawahara, Sachiyo, Sakamoto, Mayumi, Langlois, Marc-André, Neuberger, Michael S., Rada, Cristina, ...

Several members of the apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like complex 3 (APOBEC3) family in primates act as potent inhibitors of retroviral replication. However, lentiviruses...