Aberrant promoter hypermethylation in serum DNA from patients with silicosis (2008)
Umemura, Shigeki, Fujimoto, Nobukazu, Hiraki, Akio, Gemba, Kenichi, Takigawa, Nagio, Fujiwara, Keiichi, ...
It is well established that patients with silicosis are at high risk for lung cancer; however, it is difficult to detect lung cancer by chest radiography during follow-up treatment of patients with...
Matsuo, Keisuke, Kiura, Katsuyuki, Ueoka, Hiroshi, Tabata, Masahiro, Shibayama, Takuo, Matsumura, Tadashi, ...
We have established an Adriamycin (ADM) -resistant small cell lung cancer (SCLC) cell line, SBC-3/ADM100, which shows multifactorial mechanisms of resistance to ADM, such as overexpression of...
Tabata, Masahiro, Ohnoshi, Taisuke, Ueoka, Hiroshi, Kiura, Katsuyuki, Kimura, Ikuro
We report a preliminary study to determine whether MDR1 gene expression level in small cell lung cancer (SCLC) tumors is a useful predictor of tumor response to chemotherapy and patient survival in...
Yonei, Toshiro, Ohnoshi, Taisuke, Hiraki, Shunkichi, Ueoka, Hiroshi, Kiura, Katsuyuki, Moritaka, Tomonori, ...
Antitumor activities of five platinum analogs, including cisplatin, carboplatin, 254-S, DWA2114R, and NK121, were compared using five human lung cancer cell lines and 19 tumor specimens obtained from...
Kiura, Katsuyuki, Ohnoshi, Taisuke, Tabata, Masahiro, Shibayama, Takuo, Kimura, Ikuro
A subline highly resistant to Adriamycin (SBC-3/ADM100) was isolated in vitro from the human small cell lung cancer cell line, SBC-3, by culturing in progressively higher concentrations of...
Kiura, Katsuyuki, Ohnoshi, Taisuke, Tabata, Masahiro, Shibayama, Takuo, Kimura, Ikuro
A subline highly resistant to Adriamycin (SBC-3/ADM100) was isolated in vitro from the human small cell lung cancer cell line, SBC-3, by culturing in progressively higher concentrations of...
Segawa, Yoshihiko, Ohnoshi, Taisuke, Hiraki, Shunkichi, Ueoka, Hiroshi, Kiura, Katsuyuki, Kamei, Haruhito, ...
In an attempt to elucidate the tumor properties relating to responsiveness to chemotherapy, we examined immunohistochemically the expression of P-glycoprotein (P-gp) and carcinoembryonic antigen...
Prognostic factors of small-cell lung cancer in Okayama Lung Cancer Study Group Trials. (2007)
Tamura, Makoto, Ueoka, Hiroshi, Kiura, Katsuyuki, Tabata, Masahiro, Shibayama, Takuo, Miyatake, Kazuyo, ...
In order to elucidate factors influencing the prognosis of small-cell lung cancer (SCLC), we reviewed the records of 253 patients with SCLC and evaluated 20 pretreatment prognostic factors by...
Suzaki, Noriyuki, Hiraki, Akio, Takigawa, Nagio, Ueoka, Hiroshi, Tanimoto, Yasushi, Kozuki, Toshiyuki, ...
A 71-year-old Japanese man with adenocarcinoma of the lung developed interstitial pneumonia after treatment with paclitaxel. The patient had acute chills and fever on the fourth day after the second...
Takata, Ichiro, Ueoka, Hiroshi, Kiura, Katsuyuki, Tabata, Masahiro, Takigawa, Nagio, Katayama, Hideki, ...
A pilot study was conducted to assess the efficacy and feasibility of daily low-dose cisplatin with concurrent thoracic irradiation for clinically unresectable non-small-cell lung cancer (NSCLC)....
Comparison of chemosensitivity tests: clonogenic assay versus MTT assay. (2006)
Kawada, Kazuhiko, Yonei, Toshiro, Ueoka, Hiroshi, Kiura, Katsuyuki, Tabata, Masahiro, Takigawa, Nagio, ...
When the development of chemotherapeutic agents reaches the clinical trial stage, it is necessary to perform drug sensitivity tests quickly in order to select the most promising agents for the...
Kitajima, Takuji, Nishii, Kenji, Ueoka, Hiroshi, Shibayama, Takuo, Gemba, Kenichi, Kodani, Tsuyoshi, ...
To evaluate recent improvements in lung cancer screening, we compared the results of recently conducted lung cancer screening with those of a previous screening. This study compared the survival of...
Establishment of a Drug Sensitivity Panel Using Human Lung Cancer Cell Lines (2006)
Matsushita, Akio, Tabata, Masahiro, Ueoka, Hiroshi, Kiura, Katsuyuki, Shibayama, Takuo, Aoe, Keisuke, ...
We established a drug sensitivity panel consisting of 24 human lung cancer cell lines. Using this panel, we evaluated 26 anti-cancer agents: three alkylators, three platinum compounds, four...
Uchida, Akiko, Tabata, Masahiro, Kiura, Katsuyuki, Tanimoto, Yasushi, Kanehiro, Arihiko, Aoe, Motoi, ...
We describe a case of 63-year-old woman with pulmonary artery sarcoma successfully treated with chemotherapy. She developed acute shortness of breath, and left chest and shoulder pain. Although a...
Uchida, Akiko, Tabata, Masahiro, Kiura, Katsuyuki, Tanimoto, Yasushi, Kanehiro, Arihiko, Aoe, Motoi, ...
We describe a case of 63-year-old woman with pulmonary artery sarcoma successfully treated with chemotherapy. She developed acute shortness of breath, and left chest and shoulder pain. Although a...
Uchida, Akiko, Tabata, Masahiro, Kiura, Katsuyuki, Tanimoto, Yasushi, Kanehiro, Arihiko, Aoe, Motoi, ...
We describe a case of 63-year-old woman with pulmonary artery sarcoma successfully treated with chemotherapy. She developed acute shortness of breath, and left chest and shoulder pain. Although a...
Maeda, Tadashi, Ueoka, Hiroshi, Tabata, Masahiro, Kiura, Katsuyuki, Shibayama, Takuo, Gemba, Kenichi, ...
Background: Non-small cell lung cancer (NSCLC) is resistant to chemotherapy and prognosis of advanced NSCLC patients is considered to be dependent on various prognostic factors. Methods: We analyzed...