Kanegae, Kaori, Tamura, Masahito, Kabashima, Narutoshi, Serino, Ryota, Tokunaga, Masaki, Oikawa, Shigeru, ...
Background. Growth factors, extracellular matrix and its receptor integrins are upregulated in various glomerular diseases. We investigated the mechanism of collaboration between integrins and...
Kanegae, Kaori, Tamura, Masahito, Kabashima, Narutoshi, Serino, Ryota, Tokunaga, Masaki, Oikawa, Shigeru, ...
Background. Growth factors, extracellular matrix and its receptor integrins are upregulated in various glomerular diseases. We investigated the mechanism of collaboration between integrins and...
Kanegae, Kaori, Tamura, Masahito, Kabashima, Narutoshi, Serino, Ryota, Tokunaga, Masaki, Oikawa, Shigeru, ...
Background. Growth factors, extracellular matrix and its receptor integrins are upregulated in various glomerular diseases. We investigated the mechanism of collaboration between integrins and...
PTEN Gene and Integrin Signaling in Cancer (1999)
Tamura, Masahito, Gu, Jianguo, Tran, Huan, Yamada, Kenneth M.
Integrins are major adhesion- and signaling-receptor proteins that mediate cell migration and invasion. They also trigger a variety of signal transduction pathways and regulate cytoskeletal...
Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems
Podsypanina, Katrina, Ellenson, Lora Hedrick, Nemes, Adriana, Gu, Jianguo, Tamura, Masahito, Yamada, Kenneth M., ...
Pten/Mmac1+/− heterozygous mice exhibited neoplasms in multiple organs including the endometrium, liver, prostate, gastrointestinal tract, thyroid, and thymus. Loss of the wild-type allele was...
Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems
Podsypanina, Katrina, Ellenson, Lora Hedrick, Nemes, Adriana, Gu, Jianguo, Tamura, Masahito, Yamada, Kenneth M., ...
Pten/Mmac1+/− heterozygous mice exhibited neoplasms in multiple organs including the endometrium, liver, prostate, gastrointestinal tract, thyroid, and thymus. Loss of the wild-type allele was...
Gu, Jianguo, Tamura, Masahito, Yamada, Kenneth M.
The tumor suppressor PTEN dephosphorylates focal adhesion kinase (FAK) and inhibits integrin-mediated cell spreading and cell migration. We demonstrate here that expression of PTEN selectively...
Shc and Fak Differentially Regulate Cell Motility and Directionality Modulated by Pten
Gu, Jianguo, Tamura, Masahito, Pankov, Roumen, Danen, Erik H.J., Takino, Takahisa, Matsumoto, Kazue, ...
Cell migration is modulated by regulatory molecules such as growth factors, oncogenes, and the tumor suppressor PTEN. We previously described inhibition of cell migration by PTEN and restoration of...