Kato, Yuzuru, Kaneda, Masahiro, Hata, Kenichiro, Kumaki, Kenji, Hisano, Mizue, Kohara, Yuji, ...
DNA methylation is an important epigenetic modification regulating various biological phenomena, including genomic imprinting and transposon silencing. It is known that methylation of the...
Sakamaki, Kazuhiro, Nozaki, Masami, Kominami, Katsuya, Satou, Yutaka
Abstract Background Death receptors on the cell surface and the interacting cytosolic molecules, adaptors and initiator caspases, are essential as core components of the extrinsic apoptotic signaling...
Somboonthum, Pranee, Ohta, Hiroshi, Yamada, Shuichi, Onishi, Masayoshi, Ike, Akiko, Nishimune, Yoshitake, ...
Promoters, including neither TATA box nor initiator, have been frequently found in testicular germ cell-specific genes in mice. These investigations imply that unique forms of the polymerase II...
Hisano, Mizue, Ohta, Hiroshi, Nishimune, Yoshitake, Nozaki, Masami
Methylation of CpG islands spanning promoter regions is associated with control of gene expression. However, it is considered that methylation of exonic CpG islands without promoter is not related to...
Cloning and characterization of the human tektin-t gene (2002)
Iguchi, Naoko, Tanaka, Hiromitsu, Nakamura, Yoshihiro, Nozaki, Masami, Fujiwara, Tsutomu, Nishimune, Yoshitake
Tektin-t is a part of the tektin protein family, the members of which form filamentous polymers in the walls of ciliary and flagellar microtubules. In mice, tektin-t protein has been localized to the...
Wakabayashi, Nobunao, Kageyama, Ryoichiro, Habu, Toshiyuki, Doi, Toshihide, Morita, Takashi, Nozaki, Masami, ...
The regulatory mechanisms of mammalian hairy and Enhancer of split homologue-1 (HES-1) genes were examined in mouse P19 embryonic carcinoma cells (P19 cells). Undifferentiated P19 stem cells...
Fujimura, Yasuo, Yamamoto, Hideyuki, Hamazato, Fumiaki, Nozaki, Masami
Expression of the mouse cytokeratin EndoA gene is restricted in endodermal and epithelial cells, and Is regulated by an enhancer that is located 1 kilobase (kb) 3' downstream from the gene. The...
The promoter of the endo A cytokeratin gene is activated by a 3' downstream enhancer (1991)
Takemoto, Yoshihiro, Fujimura, Yasuo, Matsumoto, Midori, Tamai, Yoshitaka, Morita, Takashi, Matsushiro, Aizo, ...
Mouse cytokeratin EndoA is an intermediate filament subunit of the type II cytokeratin class which initiates expression in trophectoderm cells of blastocyst during embryogenesis. To identify the...
Polyadenylated and 3' processed mRNAs are transcribed from the mouse histone H2A.X gene (1991)
Nagata, Toshi, Kato, Tomohisa, Morita, Takashi, Nozaki, Masami, Kubota, Hiroshi, Yagi, Hirotaka, ...
We have Isolated a cDNA clone encoding a mouse histone H2A.X from a cDNA library of teratocarcinoma F9 cells. The predicted amlno acid sequence of this clone is 97% identical to human histone H2A.X....
Hisano, Mizue, Ohta, Hiroshi, Nishimune, Yoshitake, Nozaki, Masami
Methylation of CpG islands spanning promoter regions is associated with control of gene expression. However, it is considered that methylation of exonic CpG islands without promoter is not related to...
Tachibana, Makoto, Sugimoto, Kenji, Nozaki, Masami, Ueda, Jun, Ohta, Tsutomu, Ohki, Misao, ...
Covalent modification of histone tails is crucial for transcriptional regulation, mitotic chromosomal condensation, and heterochromatin formation. Histone H3 lysine 9 (H3-K9) methylation catalyzed by...
In Vitro and In Vivo Gene Delivery by Recombinant Baculoviruses
Tani, Hideki, Limn, Chang Kwang, Yap, Chan Choo, Onishi, Masayoshi, Nozaki, Masami, Nishimune, Yoshitake, ...
Although recombinant baculovirus vectors can be an efficient tool for gene transfer into mammalian cells in vitro, gene transduction in vivo has been hampered by the inactivation of baculoviruses by...
Somboonthum, Pranee, Ohta, Hiroshi, Yamada, Shuichi, Onishi, Masayoshi, Ike, Akiko, Nishimune, Yoshitake, ...
Promoters, including neither TATA box nor initiator, have been frequently found in testicular germ cell-specific genes in mice. These investigations imply that unique forms of the polymerase II...
Hisano, Mizue, Ohta, Hiroshi, Nishimune, Yoshitake, Nozaki, Masami
Methylation of CpG islands spanning promoter regions is associated with control of gene expression. However, it is considered that methylation of exonic CpG islands without promoter is not related to...
Tachibana, Makoto, Sugimoto, Kenji, Nozaki, Masami, Ueda, Jun, Ohta, Tsutomu, Ohki, Misao, ...
Covalent modification of histone tails is crucial for transcriptional regulation, mitotic chromosomal condensation, and heterochromatin formation. Histone H3 lysine 9 (H3-K9) methylation catalyzed by...
In Vitro and In Vivo Gene Delivery by Recombinant Baculoviruses
Tani, Hideki, Limn, Chang Kwang, Yap, Chan Choo, Onishi, Masayoshi, Nozaki, Masami, Nishimune, Yoshitake, ...
Although recombinant baculovirus vectors can be an efficient tool for gene transfer into mammalian cells in vitro, gene transduction in vivo has been hampered by the inactivation of baculoviruses by...
Somboonthum, Pranee, Ohta, Hiroshi, Yamada, Shuichi, Onishi, Masayoshi, Ike, Akiko, Nishimune, Yoshitake, ...
Promoters, including neither TATA box nor initiator, have been frequently found in testicular germ cell-specific genes in mice. These investigations imply that unique forms of the polymerase II...
Cytokeratins 8 and 19 in the Mouse Placental Development
Tamai, Yoshitaka, Ishikawa, Tomo-o, Bösl, Michael R., Mori, Masahiko, Nozaki, Masami, Baribault, Heléne, ...
To investigate the expression and biological roles of cytokeratin 19 (K19) in development and in adult tissues, we inactivated the mouse K19 gene (Krt1-19) by inserting a bacterial β-galactosidase...
Functional dynamics of H3K9 methylation during meiotic prophase progression
Tachibana, Makoto, Nozaki, Masami, Takeda, Naoki, Shinkai, Yoichi
Histone H3 lysine 9 (H3K9) methylation is a crucial epigenetic mark of heterochromatin formation and transcriptional silencing. G9a is a major mammalian H3K9 methyltransferase at euchromatin and is...