Yamada, Hidetaka, Shinmura, Kazuya, Goto, Masanori, Iwaizumi, Moriya, Konno, Hiroyuki, Kataoka, Hideki, ...
Abstract Background Germline mono-allelic promoter hypermethylation of the MLH1 or MSH2 gene in families with hereditary nonpolyposis colorectal cancer has recently been reported. The purpose of this...
Kuroiwa, Yuichi, Yamada, Masami, Matsui, Keiko, Okamura, Toshiya, Ishii, Yuji, Masumura, Ken-ichi, ...
Combination treatment with sodium nitrite (NaNO2) and ascorbic acid (AsA) is well known to promote forestomach carcinogenesis in rats and weakly enhance esophageal carcinogenesis under acid reflux...
Mori, Daisuke, Yano, Yoshihisa, Toyo-oka, Kazuhito, Yoshida, Noriyuki, Yamada, Masami, Muramatsu, Masami, ...
NDEL1 is a binding partner of LIS1 that participates in the regulation of cytoplasmic dynein function and microtubule organization during mitotic cell division and neuronal migration. NDEL1...
Cellular Requirements for CRM1 Import and Export (2003)
Zhang, Xianfeng, Yamada, Masami, Mabuchi, Naoto, Shida, Hisatoshi
We studied the cellular requirements for the translocation of CRM1 (exportin 1) between the nucleus and the cytoplasm. CRM1 import requires neither ATP, Ran, Ran-dependent GTP hydrolysis, nor a...
Kushida, Hirotaka, Fujita, Ken-ichi, Suzuki, Akihiro, Yamada, Masami, Endo, Toru, Nohmi, Takehiko, ...
A Salmonella typhimurium tester strain YG7108 2E1/OR co-expressing human CYP2E1 together with human NADPH-cytochrome P450 reductase (OR) was established. The mutagen-activating capacity of human...
Masumura, Ken-ichi, Matsui, Keiko, Yamada, Masami, Horiguchi, Mieko, Ishida, Kaori, Watanabe, Masahiko, ...
Mutations induced by one of the typical dietary mutagens/carcinogens, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), were characterized using gpt delta transgenic mice. This...
Kim, Su-Ryang, Maenhaut-Michel, Geneviéve, Yamada, Masami, Yamamoto, Yoshihiro, Matsui, Keiko, Sofuni, Toshio, ...
dinP is an Escherichia coli gene recently identified at 5.5 min of the genetic map, whose product shows a similarity in amino acid sequence to the E. coli UmuC protein involved in DNA damage-induced...
In Vitro and In Vivo Activities of Tea Catechins against Helicobacter pylori
Mabe, Katsuhiro, Yamada, Masami, Oguni, Itaro, Takahashi, Tsuneo
The catechin epigallocatechin gallate showed the strongest activity of the six tea catechins tested against Helicobacter pylori (MIC for 50% of the strains tested, 8 μg/ml). It had bactericidal...
Hakata, Yoshiyuki, Yamada, Masami, Shida, Hisatoshi
Rat models of human T-cell leukemia virus type 1 (HTLV-1)-related diseases such as adult T-cell leukemia and HTLV-1-associated myelopathy/tropical spastic paraparesis have been reported. However,...
Hakata, Yoshiyuki, Yamada, Masami, Shida, Hisatoshi
Human CRM1 (hCRM1) functions in the Rex-mediated mRNA export of human T-cell leukemia virus type 1 (HTLV-1) as an export receptor and as an inducing factor for Rex multimerization on its cognate RNA....
Hakata, Yoshiyuki, Yamada, Masami, Mabuchi, Naoto, Shida, Hisatoshi
The human immunodeficiency virus type 1 (HIV-1) regulatory protein, Rev, mediates the nuclear export of unspliced and singly spliced viral mRNAs by bridging viral RNA and export receptor human CRM1...
Yamada, Masami, Nunoshiba, Tatsuo, Shimizu, Masatomi, Gruz, Petr, Kamiya, Hiroyuki, Harashima, Hideyoshi, ...
Escherichia coli DNA polymerase IV incorporated 2-hydroxy-dATP opposite template guanine or thymine and 8-hydroxy-dGTP exclusively opposite adenine in vitro. Mutator phenotypes in sod/fur strains...
Kim, Su-Ryang, Maenhaut-Michel, Geneviéve, Yamada, Masami, Yamamoto, Yoshihiro, Matsui, Keiko, Sofuni, Toshio, ...
dinP is an Escherichia coli gene recently identified at 5.5 min of the genetic map, whose product shows a similarity in amino acid sequence to the E. coli UmuC protein involved in DNA damage-induced...
In Vitro and In Vivo Activities of Tea Catechins against Helicobacter pylori
Mabe, Katsuhiro, Yamada, Masami, Oguni, Itaro, Takahashi, Tsuneo
The catechin epigallocatechin gallate showed the strongest activity of the six tea catechins tested against Helicobacter pylori (MIC for 50% of the strains tested, 8 μg/ml). It had bactericidal...
Hakata, Yoshiyuki, Yamada, Masami, Shida, Hisatoshi
Rat models of human T-cell leukemia virus type 1 (HTLV-1)-related diseases such as adult T-cell leukemia and HTLV-1-associated myelopathy/tropical spastic paraparesis have been reported. However,...
Hakata, Yoshiyuki, Yamada, Masami, Mabuchi, Naoto, Shida, Hisatoshi
The human immunodeficiency virus type 1 (HIV-1) regulatory protein, Rev, mediates the nuclear export of unspliced and singly spliced viral mRNAs by bridging viral RNA and export receptor human CRM1...
Hakata, Yoshiyuki, Yamada, Masami, Shida, Hisatoshi
Human CRM1 (hCRM1) functions in the Rex-mediated mRNA export of human T-cell leukemia virus type 1 (HTLV-1) as an export receptor and as an inducing factor for Rex multimerization on its cognate RNA....
Yamada, Masami, Nunoshiba, Tatsuo, Shimizu, Masatomi, Gruz, Petr, Kamiya, Hiroyuki, Harashima, Hideyoshi, ...
Escherichia coli DNA polymerase IV incorporated 2-hydroxy-dATP opposite template guanine or thymine and 8-hydroxy-dGTP exclusively opposite adenine in vitro. Mutator phenotypes in sod/fur strains...
Mori, Daisuke, Yano, Yoshihisa, Toyo-oka, Kazuhito, Yoshida, Noriyuki, Yamada, Masami, Muramatsu, Masami, ...
NDEL1 is a binding partner of LIS1 that participates in the regulation of cytoplasmic dynein function and microtubule organization during mitotic cell division and neuronal migration. NDEL1...
Yamada, Masami, Ishikawa, Tomohisa, Fujimori, Akira, Goto, Katsutoshi
The mechanism of neurogenic regulation of skeletal muscle circulation was studied in the hindlimb of anaesthetized rats in vivo. Regional blood flow (RBF) of the hindlimb was recorded with a pulsed...
Yamada, Masami, Ishikawa, Tomohisa, Yamanaka, Akihiro, Fujimori, Akira, Goto, Katsutoshi
The mechanism of release of calcitonin gene-related peptide (CGRP) from sensory nerves in response to skeletal muscle contraction was investigated in the rat hindlimb in vivo and in vitro.In the...
Galhardo, Rodrigo S., Do, Robert, Yamada, Masami, Friedberg, Errol C., Hastings, P. J., Nohmi, Takehiko, ...
Stress-induced mutagenesis is a collection of mechanisms observed in bacterial, yeast, and human cells in which adverse conditions provoke mutagenesis, often under the control of stress responses....
Yamada, Hidetaka, Shinmura, Kazuya, Goto, Masanori, Iwaizumi, Moriya, Konno, Hiroyuki, Kataoka, Hideki, ...
LIS1 and NDEL1 coordinate the plus-end-directed transport of cytoplasmic dynein
Yamada, Masami, Toba, Shiori, Yoshida, Yuko, Haratani, Koji, Mori, Daisuke, Yano, Yoshihisa, ...
LIS1 was first identified as a gene mutated in human classical lissencephaly sequence. LIS1 is required for dynein activity, but the underlying mechanism is poorly understood. Here, we demonstrate...