Masao Yamada

Mutations of the PAX6 Gene Detected in Patients with a Variety (2008)

Eriko Kawase, Masao Yamada

The PAX6 gene is involved in ocular morphogenesis and is expressed in the developing central nervous system and numerous ocular tissues during development. PAX6 mutations have been detected in...

Neurovirulent strains of herpes simplex virus type 1 are not necessarily competent for reactivatable latency. (2007)

Arao, Yujiro, Hatano, Atsushi, Yamada, Masao, Uno, Fumio, Nii, Shiro

Ability of two neurovirulent strains (F and +GC (LPV) Miyama) of herpes simplex virus type 1 (HSV-1) to establish and maintain reactivatable latency in trigeminal ganglia (TG) was compared after...

Reactivatable latency of three avirulent strains of herpes simplex virus type 1 after intranasal inoculation in mice. (2007)

Arao, Yujiro, Hatano, Atsushi, Yamada, Masao, Uno, Fumio, Nii, Shiro

In order to elucidate the mechanism of latent infection of herpes simplex virus (HSV), reactivatable latency of three avirulent strains (SKO-1B, -GCr Miyama, SKa) of HSV type 1 was comparatively...

Induction and prevention of virus-associated malignant lymphoma by serial transmission of EBV-related virus from cynomolgus by blood transfusion in rabbits. (2006)

Koirala, Tirtha Raj, Hayashi, Kazuhiko, Jin, Zaishun, Onoda, Sachiyo, Tanaka, Takehiro, Oda, Wakako, ...

Epstein-Barr virus (EBV)-related herpesvirus (Si-IIA-EBV) was serially transmitted for 3 passages from rabbit to rabbit of the opposite sex by blood transfusion, which subsequently induced...

Induction of tumour necrosis factor receptor-expressing macrophages by interleukin-10 and macrophage colony-stimulating factor in rheumatoid arthritis (2006)

Takasugi, Koji, Yamamura, Masahiro, Iwahashi, Mitsuhiro, Otsuka, Fumio, Yamana, Jiro, Sunahori, Katsue, ...

Abstract Despite its potent ability to inhibit proinflammatory cytokine synthesis, interleukin (IL)-10 has a marginal clinical effect in rheumatoid arthritis (RA) patients. Recent evidence suggests...

Application of Lectin Microarray to Crude Samples: Differential Glycan Profiling of Lec Mutants (2006)

Ebe, Youji, Kuno, Atsushi, Uchiyama, Noboru, Koseki-Kuno, Shiori, Yamada, Masao, Sato, Takashi, ...

We recently developed a novel system for lectin microarray based on the evanescent-field fluorescence-detection principle, by which even weak lectin-oligosaccharide interactions are detectable...

Rapid Communication Application of Lectin Microarray to Crude Samples: Differential Glycan Profiling of Lec Mutants (2005)

J. Biochem, Youji Ebe, Atsushi Kuno, Noboru Uchiyama, Shiori Koseki-kuno, Masao Yamada, ...

We recently developed a novel system for lectin microarray based on the evanescentfield fluorescence-detection principle, by which even weak lectin-oligosaccharide interactions are detectable without...

Detecting tissue-specific alternative splicing and disease-associated aberrant splicing of the PTCH gene with exon junction microarrays (2005)

Nagao, Kazuaki, Togawa, Naoyuki, Fujii, Katsunori, Uchikawa, Hideki, Kohno, Yoichi, Yamada, Masao, ...

Mutations in the human ortholog of Drosophila patched (PTCH) have been identified in patients with autosomal dominant nevoid basal cell carcinoma syndrome (NBCCS), characterized by minor...

The Pax6 isoform bearing an alternative spliced exon promotes the development of the neural retinal structure (2005)

Azuma, Noriyuki, Tadokoro, Keiko, Asaka, Astuko, Yamada, Masao, Yamaguchi, Yuki, Handa, Hiroshi, ...

The vertebrate retina has an area where visual cells are closely packed for proper vision that is known as a fovea, an area centralis or a visual streak. The molecular mechanism that regulates the...

Transdifferentiation of the retinal pigment epithelia to the neural retina by transfer of the Pax6 transcriptional factor (2005)

Azuma, Noriyuki, Tadokoro, Keiko, Asaka, Astuko, Yamada, Masao, Yamaguchi, Yuki, Handa, Hiroshi, ...

The Pax6 gene plays an important role in eye morphogenesis throughout the animal kingdom. The Pax6 gene and its homologue could form ectopic eyes by targeted expression in Drosophila and Xenopus....

The Pax6 isoform bearing an alternative spliced exon promotes the development of the neural retinal structure (2005)

Azuma, Noriyuki, Tadokoro, Keiko, Asaka, Astuko, Yamada, Masao, Yamaguchi, Yuki, Handa, Hiroshi, ...

The vertebrate retina has an area where visual cells are closely packed for proper vision that is known as a fovea, an area centralis, or a visual streak. The molecular mechanism that regulates the...

Transdifferentiation of the retinal pigment epithelia to the neural retina by transfer of the Pax6 transcriptional factor (2005)

Azuma, Noriyuki, Tadokoro, Keiko, Asaka, Astuko, Yamada, Masao, Yamaguchi, Yuki, Handa, Hiroshi, ...

The Pax6 gene plays important roles in eye morphogenesis throughout the animal kingdom. The Pax6 gene and its homologue could form ectopic eyes by targeted expression in Drosophila and Xenopus. Thus,...

Detecting tissue-specific alternative splicing and disease-associated aberrant splicing of the PTCH gene with exon junction microarrays (2005)

Nagao, Kazuaki, Togawa, Naoyuki, Fujii, Katsunori, Uchikawa, Hideki, Kohno, Yoichi, Yamada, Masao, ...

Mutations in the human ortholog of Drosophila patched (PTCH) have been identified in patients with autosomal dominant nevoid basal cell carcinoma syndrome (NBCCS) characterized by minor developmental...

Dentatorubral-pallidoluysian atrophy protein is phosphorylated by c-Jun NH2-terminal kinase (2003)

Okamura-Oho, Yuko, Miyashita, Toshiyuki, Nagao, Kazuaki, Shima, Seigo, Ogata, Yukie, Katada, Toshiaki, ...

Dentatorubral-pallidoluysian atrophy (DRPLA) is a dominant-inherited neurodegenerative disease characterized by selective cell loss in particular neuronal pathways. This is caused by expansion of CAG...

Protein binding of a DRPLA family through arginine-glutamic acid dipeptide repeats is enhanced by extended polyglutamine (2000)

Yanagisawa, Hiroko, Bundo, Miki, Miyashita, Toshiyuki, Okamura-Oho, Yuko, Tadokoro, Keiko, Tokunaga, Katsushi, ...

Dentatorubral-pallidoluysian atrophy (DRPLA) is one of the hereditary neurodegenerative disorders caused by expansion of CAG/glutamine repeats. To investigate the normal function of the DRPLA...

Mutations of a human homologue of the Drosophila eyes absent gene (EYA1) detected in patients with congenital cataracts and ocular anterior segment anomalies (2000)

Azuma, Noriyuki, Hirakiyama, Asami, Inoue, Tadashi, Asaka, Atsuko, Yamada, Masao

The Drosophila eyes absent gene (eya) is involved in the formation of compound eyes. Flies with loss-of-function mutations of this gene develop no eyes and form the ectopic eye in the antennae and...

High-resolution immuno-scanning electron microscopy using a non-coating method: study of herpes simplex virus glycoproteins on the surface of virus particles and infected cells (1997)

Padilla, Jorge A., Uno, Fumio, Yamada, Masao, Namba, Hikaru, Nii, Shiro

The expression of two glycoproteins, i.e. glycoprotein C (gC) and glycoprotein D (gD), of herpes simplex virus type 1 (HSV-1) on the surface of extracellular particles of this virus was examined by...

Electron Microscopic Observations of Aberrant Capsids of Pseudorabies Virus (1996)

Muraki, Yuko, Yamada, Masao, Yoshida, Mariko, Yamada, Shunji, Padilla, Jorge, Hatano, Yoshihiro, ...

Interactions between four strains of pseudorabies virus (PrV) and seven kinds of cell lines were examined. Three kinds of cells (SKL, CPK and PK-15) were especially infected with PrV at an MOI of...

Megabase-scale analysis of the origin of N-myc amplicons in human neuroblastomas (1994)

Akiyama, Kiyotaka, Kanda, Naotoshi, Yamada, Masao, Tadokoro, Keiko, Matsunaga, Tadashi, Nishi, Yoshisuke

In order to elucidate the Initiation of the N-myc gene amplification, we have analyzed the original structures of the N-myc amplicons among 38 human neuroblastomas. Nineteen DNAs Isolated from the...

A human Y-chromosome specific repeated DNA family (DYZ1) consists of a tandem array of pentanucleotides (1986)

Nakahori, Yutaka, Mitani, Kounosuke, Yamada, Masao, Nakagome, Yasuo

We have determined the complete nucleotide sequence of a 3564 bp EcoRI fragment which represents a major component of the human γ-chromosome specific repeated DNA family (DYZ1). Sequencing result...

Nucleotide sequence of the asnA gene coding for asparagine synthetase of E.coli K-12 (1981)

Nakamura, Masataka, Yamada, Masao, Hirota, Yukinori, Sugimoto, Kazunori, Oka, Atsuhiro, Takanami, Mituru

We have subcloned the asnA gene of E. coli K-12, a gene coding for asparagine synthetase, from a previously cloned 6 mega-dalton segment of E. coli chromosome containing the DNA replication origin,...

Further Studies on Glycosidases from the Liver of Turbo cornutus with Special Reference to {beta}-Galactosidase, {alpha}-L-Arabinosidase, and {beta}-D-Fucosidase Activities (1973)

YAMADA, Masao, IKEDA, Kayoko, EGAMI, Fujio

1) Two β-galactosidase activities with pH optimum at 3.0 and 5.5 were found in the liver extract of a marine gastropod, Turbo cornutus. 2) β-Galactosidase (pH 3.0) [EC 3. 2.1. 23] was purified...

Neutralization Assay for Human Group C Rotaviruses Using a Reverse Passive Hemagglutination Test for Endpoint Determination

Fujii, Ritsushi, Kuzuya, Mitsutaka, Hamano, Masako, Ogura, Hajime, Yamada, Masao, Mori, Tadashige

A novel neutralization assay for human group C rotavirus (CHRV) was developed by using a reverse passive hemagglutination (RPHA) test for endpoint determination. In this assay, the neutralization...

Seroepidemiology of Human Group C Rotavirus in Japan Based on a Blocking Enzyme-Linked Immunosorbent Assay

Kuzuya, Mitsutaka, Fujii, Ritsushi, Hamano, Masako, Ohata, Ritsuko, Ogura, Hajime, Yamada, Masao

A novel blocking enzyme-linked immunosorbent assay (BL-ELISA) was developed for detection of antibodies to human group C rotavirus (CHRV). The specificity of the BL-ELISA was confirmed by using...

Elucidation of the Cross-Reactive Immunoglobulin M Response to Human Herpesviruses 6 and 7 on the Basis of Neutralizing Antibodies

Yoshida, Mariko, Torigoe, Sadayoshi, Yamada, Masao

Human herpesvirus 6 (HHV-6) is closely related to HHV-7 in terms of genome organization and sequence. The cross-reactive responses between HHV-6 and HHV-7 have been reported by using...

Neutralizing Antibody Responses to Human Herpesviruses 6 and 7 Do Not Cross-React with Each Other, and Maternal Neutralizing Antibodies Contribute to Sequential Infection with These Viruses in Childhood

Yoshida, Mariko, Torigoe, Sadayoshi, Ikeue, Kumiko, Yamada, Masao

Seroprevalence of human herpesvirus 6 (HHV-6) and HHV-7 infections is very high throughout the world, and almost all people are exposed first to HHV-6 and second to HHV-7 in their childhood. However,...

Survey of Human Group C Rotaviruses in Japan during the Winter of 1992 to 1993

Kuzuya, Mitsutaka, Fujii, Ritsushi, Hamano, Masako, Yamada, Masao, Shinozaki, Kuniko, Sasagawa, Akira, ...

Fecal specimens from patients with acute diarrhea were collected from 10 prefectures in Japan over a 6-month period (November 1992 to April 1993), and the specimens that were negative for human group...

Neutralization Assay for Human Group C Rotaviruses Using a Reverse Passive Hemagglutination Test for Endpoint Determination

Fujii, Ritsushi, Kuzuya, Mitsutaka, Hamano, Masako, Ogura, Hajime, Yamada, Masao, Mori, Tadashige

A novel neutralization assay for human group C rotavirus (CHRV) was developed by using a reverse passive hemagglutination (RPHA) test for endpoint determination. In this assay, the neutralization...

Seroepidemiology of Human Group C Rotavirus in Japan Based on a Blocking Enzyme-Linked Immunosorbent Assay

Kuzuya, Mitsutaka, Fujii, Ritsushi, Hamano, Masako, Ohata, Ritsuko, Ogura, Hajime, Yamada, Masao

A novel blocking enzyme-linked immunosorbent assay (BL-ELISA) was developed for detection of antibodies to human group C rotavirus (CHRV). The specificity of the BL-ELISA was confirmed by using...

Elucidation of the Cross-Reactive Immunoglobulin M Response to Human Herpesviruses 6 and 7 on the Basis of Neutralizing Antibodies

Yoshida, Mariko, Torigoe, Sadayoshi, Yamada, Masao

Human herpesvirus 6 (HHV-6) is closely related to HHV-7 in terms of genome organization and sequence. The cross-reactive responses between HHV-6 and HHV-7 have been reported by using...

Neutralizing Antibody Responses to Human Herpesviruses 6 and 7 Do Not Cross-React with Each Other, and Maternal Neutralizing Antibodies Contribute to Sequential Infection with These Viruses in Childhood

Yoshida, Mariko, Torigoe, Sadayoshi, Ikeue, Kumiko, Yamada, Masao

Seroprevalence of human herpesvirus 6 (HHV-6) and HHV-7 infections is very high throughout the world, and almost all people are exposed first to HHV-6 and second to HHV-7 in their childhood. However,...

Survey of Human Group C Rotaviruses in Japan during the Winter of 1992 to 1993

Kuzuya, Mitsutaka, Fujii, Ritsushi, Hamano, Masako, Yamada, Masao, Shinozaki, Kuniko, Sasagawa, Akira, ...

Fecal specimens from patients with acute diarrhea were collected from 10 prefectures in Japan over a 6-month period (November 1992 to April 1993), and the specimens that were negative for human group...

Mutations of the PAX6 Gene Detected in Patients with a Variety of Optic-Nerve Malformations

Azuma, Noriyuki, Yamaguchi, Yuki, Handa, Hiroshi, Tadokoro, Keiko, Asaka, Atsuko, Kawase, Eriko, ...

The PAX6 gene is involved in ocular morphogenesis and is expressed in the developing central nervous system and numerous ocular tissues during development. PAX6 mutations have been detected in...

Induction of tumour necrosis factor receptor-expressing macrophages by interleukin-10 and macrophage colony-stimulating factor in rheumatoid arthritis

Takasugi, Koji, Yamamura, Masahiro, Iwahashi, Mitsuhiro, Otsuka, Fumio, Yamana, Jiro, Sunahori, Katsue, ...

Despite its potent ability to inhibit proinflammatory cytokine synthesis, interleukin (IL)-10 has a marginal clinical effect in rheumatoid arthritis (RA) patients. Recent evidence suggests that IL-10...