Masataka Nakamura

A characterization of the edge-shelling convex geometries of trees (2009)

Kashiwabara, Kenji, Nakamura, Masataka

We investigate the class of the edge-shelling convex geometries of trees. The edge-shelling convex geometry of a tree is the convex geometry consisting of the sets of edges of the subtrees. For the...

(1) E ∈ K, (2008)

Kenji Kashiwabara, Masataka Nakamura

We introduce a notion of a broken circuit and an NBC complex for an (abstract) convex geometry. Based on these definitions, we shall show the analogues of the Whitney-Rota’s formula and...

Identification of two distinct elements mediating activation of telomerase (hTERT) gene expression in association with cell growth in human T cells (2005)

Matsumura-Arioka, Yuuki, Ohtani, Kiyoshi, Hara, Toshifumi, Iwanaga, Ritsuko, Nakamura, Masataka

Lymphocytes are exceptional among normal somatic cells in that they express high telomerase activity like germline and malignant cells. We investigated the induction of telomerase in human T cells in...

Identification of two distinct elements mediating activation of telomerase (hTERT) gene expression in association with cell growth in human T cells (2005)

Matsumura-Arioka, Yuuki, Ohtani, Kiyoshi, Hara, Toshifumi, Iwanaga, Ritsuko, Nakamura, Masataka

Lymphocytes are exceptional among normal somatic cells in that they express high telomerase activity like germline and malignant cells. We investigated the induction of telomerase in human T cells in...

Affine Representations of Abstract Convex Geometries (2003)

Kenji Kashiwabara, Masataka Nakamura, Yoshio Okamoto

A convex geometry is a combinatorial abstract model introduced by Edelman and Jamison which captures a combinatorial essence of "convexity " shared by some structures including finite point...

The Forbidden Minor Characterization of Line-Search Antimatroids of Rooted Digraphs (2002)

Yoshio Okamoto, Masataka Nakamura

An antimatroid is an accessible union-closed family of subsets of a finite set. A number of classes of antimatroids are closed under taking minors such as point-search antimatroids of rooted...

Accumulation of CRTH2-positive T-helper 2 and T-cytotoxic 2 cells at implantation sites of human decidua in a prostaglandin D2-mediated manner (2002)

Michimata, Toshihiko, Tsuda, Hiroshi, Sakai, Masatoshi, Fujimura, Masaki, Nagata, Kinya, Nakamura, Masataka, ...

T-helper (Th) 2-type cytokines predominate in decidua, plausibly accounting for protection of a semiallograft, the embryo and placenta, from attack by the maternal immune system. However,...

Sharing of the IL-2 receptor {gamma} chain with the functional IL-9 receptor complex (1995)

Kimura, Yutaka, Takeshita, Toshikazu, Kondo, Motonari, Ishii, Naoto, Nakamura, Masataka, Van Snick, Jacques, ...

The third subunit, the so-called common γ (γc) chain, of the IL-2 receptor is shared among the receptors for IL-2, IL-4, IL-7 and IL-15, and dysfunction of the γc chain is thought to cause...

Expression of the IL-2 receptor {gamma} chain on various populations in human peripheral blood (1994)

Ishil, Naoto, Takeshita, Toshikazu, Kimura, Yutaka, Tada, Kohtaro, Kondo, Motonari, Nakamura, Masataka, ...

We have established two rat mAbs, TUGH4 and TUGh5, specific for the human γ chain of the IL-2 receptor (IL-2R), which is known to be shared among receptors for IL-2, IL-4 and IL-7. The antibodies...

The evidence for the IL-2 recptor {beta} Chain processing from p70 to p75 (1990)

Asao, Hironobu, Takeshita, Toshikazu, Nakamura, Masataka, Nagata, Kinya, Sugamura, Kazuo

The biosynthesis of human interleukin 2 receptor (IL-2R)p75 was studied with TU27 monoclonal antibody (TU27 mAb) specific for the IL-2Rp75. TU27 mAb specifically immunoprecipitated not only p75 with...

Electroporation: application to human lympboid cell lines for stable introduction of a transactivator gene of human T-cell leukemia virus type I (1989)

Ohtani, Kiyoshi, Nakamura, Masataka, Saito, Shigeru, Nagata, Kinya, Sugamura, Kazuo, Hinuma, Yorio

Conditions were developed for stable introduction of foreign DNA into human lymphoid cell lines by electroporation. To introduce stably the p40 gene of human T-cell leukemia virus type I (HTLV-I)...

Differential activation of the 21-base-pair enhancer element of human T-cell leukemia virus type 1 by its own trans-activator and cyclic AMP (1989)

Nakamura, Masataka, Niki, Masaru, Ohtani, Kiyoshi, Sugamura, Kazuo

A transcriptional trans-acting factor ptax of human T-cell leukemia virus type I (HTLV-I) functions as an inducer for expression of HTLV-I provirus via activation of the enhancer in the long terminal...

Nucleotide sequence of the asnA gene coding for asparagine synthetase of E.coli K-12 (1981)

Nakamura, Masataka, Yamada, Masao, Hirota, Yukinori, Sugimoto, Kazunori, Oka, Atsuhiro, Takanami, Mituru

We have subcloned the asnA gene of E. coli K-12, a gene coding for asparagine synthetase, from a previously cloned 6 mega-dalton segment of E. coli chromosome containing the DNA replication origin,...

Mouse Spleen Cell Nuclear Protein Kinases and the Stimulating Effect of dsDNA on NHP Phosphorylation by Cyclic AMP-Independent Protein Kinase In Vitro (1980)

OHTSUKI, Kenzo, YAMADA, Ei, NAKAMURA, Masataka, ISHIDA, Nakao

cAMP-dependent (designated as enzyme I, about 68,000 daltons) and cAMP-independent protein kinase (designated as enzyme II, about 45,000 daltons) have been partially purified from the nuclei of mouse...

Common Regulation of Growth Arrest and Differentiation of Osteoblasts by Helix-Loop-Helix Factors

Funato, Noriko, Ohtani, Kiyoshi, Ohyama, Kimie, Kuroda, Takayuki, Nakamura, Masataka

Cellular differentiation entails the coordination of cell cycle arrest and tissue-specific gene expression. We investigated the involvement of basic helix-loop-helix (bHLH) factors in differentiation...

Human T-Cell Leukemia Virus Type 1 Tax Protein Abrogates Interleukin-2 Dependence in a Mouse T-Cell Line

Iwanaga, Youichi, Tsukahara, Tomonori, Ohashi, Takashi, Tanaka, Yuetsu, Arai, Masaaki, Nakamura, Masataka, ...

Human T-cell leukemia virus type 1 (HTLV-1) is the etiologic agent of adult T-cell leukemia. Tax, the viral protein, is thought to be crucial in the development of the disease, since it transforms...

Induction of Bcl-xL Expression by Human T-Cell Leukemia Virus Type 1 Tax through NF-κB in Apoptosis-Resistant T-Cell Transfectants with Tax

Tsukahara, Tomonori, Kannagi, Mari, Ohashi, Takashi, Kato, Hirotomo, Arai, Masaaki, Nunez, Gabriel, ...

Human T-cell leukemia virus type 1 (HTLV-1) Tax is thought to play a pivotal role in immortalization of T cells. We have recently shown that the expression of Tax protected the mouse T-cell line...

OX40 Stimulation by gp34/OX40 Ligand Enhances Productive Human Immunodeficiency Virus Type 1 Infection

Takahashi, Yoshiaki, Tanaka, Yuetsu, Yamashita, Atsuya, Koyanagi, Yoshio, Nakamura, Masataka, Yamamoto, Naoki

OX40 is a member of the tumor necrosis factor (TNF) receptor superfamily and known to be an important costimulatory molecule expressed on activated T cells. To investigate the role of costimulation...

Distinct E2F-mediated transcriptional program regulates p14ARF gene expression

Komori, Hideyuki, Enomoto, Mitsuru, Nakamura, Masataka, Iwanaga, Ritsuko, Ohtani, Kiyoshi

The tumor suppressor p14ARF gene is induced by ectopically expressed E2F, a positive regulator of the cell cycle. The gene is expressed at low levels in normally growing cells in contrast to high...

Common Regulation of Growth Arrest and Differentiation of Osteoblasts by Helix-Loop-Helix Factors

Funato, Noriko, Ohtani, Kiyoshi, Ohyama, Kimie, Kuroda, Takayuki, Nakamura, Masataka

Cellular differentiation entails the coordination of cell cycle arrest and tissue-specific gene expression. We investigated the involvement of basic helix-loop-helix (bHLH) factors in differentiation...

Human T-Cell Leukemia Virus Type 1 Tax Protein Abrogates Interleukin-2 Dependence in a Mouse T-Cell Line

Iwanaga, Youichi, Tsukahara, Tomonori, Ohashi, Takashi, Tanaka, Yuetsu, Arai, Masaaki, Nakamura, Masataka, ...

Human T-cell leukemia virus type 1 (HTLV-1) is the etiologic agent of adult T-cell leukemia. Tax, the viral protein, is thought to be crucial in the development of the disease, since it transforms...

Induction of Bcl-xL Expression by Human T-Cell Leukemia Virus Type 1 Tax through NF-κB in Apoptosis-Resistant T-Cell Transfectants with Tax

Tsukahara, Tomonori, Kannagi, Mari, Ohashi, Takashi, Kato, Hirotomo, Arai, Masaaki, Nunez, Gabriel, ...

Human T-cell leukemia virus type 1 (HTLV-1) Tax is thought to play a pivotal role in immortalization of T cells. We have recently shown that the expression of Tax protected the mouse T-cell line...

OX40 Stimulation by gp34/OX40 Ligand Enhances Productive Human Immunodeficiency Virus Type 1 Infection

Takahashi, Yoshiaki, Tanaka, Yuetsu, Yamashita, Atsuya, Koyanagi, Yoshio, Nakamura, Masataka, Yamamoto, Naoki

OX40 is a member of the tumor necrosis factor (TNF) receptor superfamily and known to be an important costimulatory molecule expressed on activated T cells. To investigate the role of costimulation...

Distinct E2F-mediated transcriptional program regulates p14ARF gene expression

Komori, Hideyuki, Enomoto, Mitsuru, Nakamura, Masataka, Iwanaga, Ritsuko, Ohtani, Kiyoshi

The tumor suppressor p14ARF gene is induced by ectopically expressed E2F, a positive regulator of the cell cycle. The gene is expressed at low levels in normally growing cells in contrast to high...

Interleukin 12–dependent Interferon γ Production by CD8α+Lymphoid Dendritic Cells

Ohteki, Toshiaki, Fukao, Taro, Suzue, Kazutomo, Maki, Chikako, Ito, Mamoru, Nakamura, Masataka, ...

We investigated the role of antigen-presenting cells in early interferon (IFN)-γ production in normal and recombinase activating gene 2–deficient (Rag-2−/−) mice in response to Listeria...

Prostaglandin D2 Selectively Induces Chemotaxis in T Helper Type 2 Cells, Eosinophils, and Basophils via Seven-Transmembrane Receptor Crth2

Hirai, Hiroyuki, Tanaka, Kazuya, Yoshie, Osamu, Ogawa, Kazuyuki, Kenmotsu, Kazumi, Takamori, Yasushi, ...

Prostaglandin (PG)D2, which has long been implicated in allergic diseases, is currently considered to elicit its biological actions through the DP receptor (DP). Involvement of DP in the formation of...

Continuous Hemodiafiltration with PMMA Hemofilter in the Treatment of Patients with Septic Shock

Nakada, Taka-aki, Oda, Shigeto, Matsuda, Ken-ichi, Sadahiro, Tomohito, Nakamura, Masataka, Abe, Ryuzo, ...

Septic shock is the most severe form of sepsis. It is widely accepted that cytokines play pivotal roles in the pathophysiology of septic shock. We reported previously that continuous...

Blood glucose control in patients with severe sepsis and septic shock

Hirasawa, Hiroyuki, Oda, Shigeto, Nakamura, Masataka

The main pathophysiological feature of sepsis is the uncontrollable activation of both pro- and anti-inflammatory responses arising from the overwhelming production of mediators such as pro- and...