Masato Takahashi

Swainsonine reduces 5-fluorouracil tolerance in the multistage resistance of colorectal cancer cell lines (2007)

Hamaguchi, Jun, Nakagawa, Hiroaki, Takahashi, Masato, Kudo, Takeaki, Kamiyama, Naoya, Sun, Bailong, ...

Abstract Background Drug resistance is a major problem in cancer chemotherapy. Acquisition of chemo-resistance not only reduces the effectiveness of drugs, but also promotes side effects and markedly...

N-glycan alterations are associated with drug resistance in human hepatocellular carcinoma (2007)

Kudo, Takeaki, Nakagawa, Hiroaki, Takahashi, Masato, Hamaguchi, Jun, Kamiyama, Naoya, Yokoo, Hideki, ...

Abstract Background Correlations of disease phenotypes with glycosylation changes have been analysed intensively in the tumor biology field. Glycoforms potentially associated with carcinogenesis,...

Inactivate the remaining p53 allele or the alternate p73? Preferential selection of the Arg72 polymorphism in cancers with recessive p53 mutants but not transdominant mutants (2001)

Tada, Mitsuhiro, Furuuchi, Keiji, Kaneda, Masako, Matsumoto, Joe, Takahashi, Masato, Hirai, Atsuko, ...

Several reports have noted epidemiological differences in the prevalence or prognostic significance of p53 mutants with arginine (R) or proline (P) at the codon 72 polymorphism (R72/P72) in certain...

Pulmonary vasoreactivity in animals with relatively increased pulmonary blood flow (1970)

Linde, Leonard M., Goldberg, Stanley J., Takahashi, Masato, Momma, Kazua, Groveman, George

Authors' synopsisPulmonary haemodynamics and vasoreactivity to pentobarbital and thiamylal were measured in dogs with normal and increased lung blood flow. Pressure response and vasoreactivity were...

Effects of Barbiturates on Pulmonary and Systemic Haemodynamics (1968)

Goldberg, Stanley J., Linde, Leonard M., Gaal, Peter G., Momma, Kazuo, Takahashi, Masato, Sarna, Gregory

Authors' SynopsisPulmonary and systemic haemodynamic effects of intravenously administered thiamylal and pentobarbital were investigated in intact, unsedated, instrumented dogs. The predominant...

Autoinhibitory Regulation of p73 by ΔNp73 To Modulate Cell Survival and Death through a p73-Specific Target Element within the ΔNp73 Promoter

Nakagawa, Takahito, Takahashi, Masato, Ozaki, Toshinori, Watanabe, Ken-ichi, Todo, Satoru, Mizuguchi, Hiroyuki, ...

p73 is a p53-related tumor suppressor but is also induced by oncogene products such as E2F-1, raising a question as to whether p73 is a tumor suppressor gene or oncogene. Unlike p53, p73 has several...

Autoinhibitory Regulation of p73 by ΔNp73 To Modulate Cell Survival and Death through a p73-Specific Target Element within the ΔNp73 Promoter

Nakagawa, Takahito, Takahashi, Masato, Ozaki, Toshinori, Watanabe, Ken-ichi, Todo, Satoru, Mizuguchi, Hiroyuki, ...

p73 is a p53-related tumor suppressor but is also induced by oncogene products such as E2F-1, raising a question as to whether p73 is a tumor suppressor gene or oncogene. Unlike p53, p73 has several...

AFP mRNA Detected in Bone Marrow by Real-Time Quantitative RT-PCR Analysis Predicts Survival and Recurrence After Curative Hepatectomy for Hepatocellular Carcinoma

Kamiyama, Toshiya, Takahashi, Masato, Nakagawa, Takahito, Nakanishi, Kazuaki, Kamachi, Hirofumi, Suzuki, Tomomi, ...

Hepatocellular carcinoma cells were perioperatively detected by real-time quantitative RT-PCR targeting AFP mRNA in bone marrow and peripheral blood of HCC patients who underwent curative...

Somatic Mutations of the APC Gene in Primary Breast Cancers

Furuuchi, Keiji, Tada, Mitsuhiro, Yamada, Hidehisa, Kataoka, Akihiko, Furuuchi, Narumi, Hamada, Jun-ichi, ...

APC gene mutations play an important role in the initiation step of colorectal carcinogenesis in both familial adenomatous polyposis (FAP) patients and non-FAP patients. Although the APC gene is...