Hair loss and defective T- and B-cell function in mice lacking ORAI1 (2008)
Gwack, Yousang, Srikanth, Sonal, Oh-Hora, Masatsugu, Hogan, Patrick G., Lamperti, Edward D., Yamashita, Megumi, ...
ORAI1 is a pore subunit of the store-operated Ca(2+) release-activated Ca(2+) (CRAC) channel. To examine the physiological consequences of ORAI1 deficiency, we generated mice with targeted disruption...
Aiba, Yuichi, Oh-hora, Masatsugu, Kiyonaka, Shigeki, Kimura, Yayoi, Hijikata, Atsushi, Mori, Yasuo, ...
The Ras signaling pathway plays a critical role in B lymphocyte development and activation, but its activation mechanism has not been well understood. At least one mode of Ras regulation in B cells...
Aiba, Yuichi, Oh-hora, Masatsugu, Kiyonaka, Shigeki, Kimura, Yayoi, Hijikata, Atsushi, Mori, Yasuo, ...
The Ras signaling pathway plays a critical role in B lymphocyte development and activation, but its activation mechanism has not been well understood. At least one mode of Ras regulation in B cells...
Oh-hora, Masatsugu, Johmura, Sachiko, Hashimoto, Ari, Hikida, Masaki, Kurosaki, Tomohiro
Two important Ras guanine nucleotide exchange factors, Son of sevenless (Sos) and Ras guanine nucleotide releasing protein (RasGRP), have been implicated in controlling Ras activation when cell...
Barr, Valarie A., Bernot, Kelsie M., Srikanth, Sonal, Gwack, Yousang, Balagopalan, Lakshmi, Regan, Carole K., ...
The proteins STIM1 and Orai1 are the long sought components of the store-operated channels required in T-cell activation. However, little is known about the interaction of these proteins in T-cells...
Hair Loss and Defective T- and B-Cell Function in Mice Lacking ORAI1▿ †
Gwack, Yousang, Srikanth, Sonal, Oh-hora, Masatsugu, Hogan, Patrick G., Lamperti, Edward D., Yamashita, Megumi, ...
ORAI1 is a pore subunit of the store-operated Ca2+ release-activated Ca2+ (CRAC) channel. To examine the physiological consequences of ORAI1 deficiency, we generated mice with targeted disruption of...