Matthew A. Williams

Publication List Details

Period

1997 - 2008

Number

8

Co-Authors

CUTTING EDGE THE JOURNAL OF IMMUNOLOGY Cutting Edge: A Single MHC Class Ia Is Sufficient for CD8 (2008)

Matthew A. Williams, Michael J. Bevan

Recent studies have suggested a role for MHC class Ib molecules in providing signals for memory T cell differentiation during the early phases of acute infection. To test this hypothesis, we assessed...

Oral Administration of a Prodrug of the Influenza Virus Neuraminidase Inhibitor GS 4071 Protects Mice and Ferrets against Influenza Infection

Mendel, Dirk B., Tai, Chun Y., Escarpe, Paul A., Li, Weixing, Sidwell, Robert W., Huffman, John H., ...

We have recently described GS 4071, a carbocyclic transition-state analog inhibitor of the influenza virus neuraminidase, which has potent inhibitory activity comparable to that of...

Characterization of Human Influenza Virus Variants Selected In Vitro in the Presence of the Neuraminidase Inhibitor GS 4071

Tai, Chun Y., Escarpe, Paul A., Sidwell, Robert W., Williams, Matthew A., Lew, Willard, Wu, Huiwei, ...

An oral prodrug of GS 4071, a potent and selective inhibitor of influenza neuraminidases, is currently under clinical development for the treatment and prophylaxis of influenza virus infections in...

Heterologous immunity provides a potent barrier to transplantation tolerance

Adams, Andrew B., Williams, Matthew A., Jones, Thomas R., Shirasugi, Nozomu, Durham, Megan M., Kaech, Susan M., ...

Many strategies have been proposed to induce tolerance to transplanted tissue in rodents; however, few if any have shown equal efficacy when tested in nonhuman primate transplant models. We...

Oral Administration of a Prodrug of the Influenza Virus Neuraminidase Inhibitor GS 4071 Protects Mice and Ferrets against Influenza Infection

Mendel, Dirk B., Tai, Chun Y., Escarpe, Paul A., Li, Weixing, Sidwell, Robert W., Huffman, John H., ...

We have recently described GS 4071, a carbocyclic transition-state analog inhibitor of the influenza virus neuraminidase, which has potent inhibitory activity comparable to that of...

Characterization of Human Influenza Virus Variants Selected In Vitro in the Presence of the Neuraminidase Inhibitor GS 4071

Tai, Chun Y., Escarpe, Paul A., Sidwell, Robert W., Williams, Matthew A., Lew, Willard, Wu, Huiwei, ...

An oral prodrug of GS 4071, a potent and selective inhibitor of influenza neuraminidases, is currently under clinical development for the treatment and prophylaxis of influenza virus infections in...

Heterologous immunity provides a potent barrier to transplantation tolerance

Adams, Andrew B., Williams, Matthew A., Jones, Thomas R., Shirasugi, Nozomu, Durham, Megan M., Kaech, Susan M., ...

Many strategies have been proposed to induce tolerance to transplanted tissue in rodents; however, few if any have shown equal efficacy when tested in nonhuman primate transplant models. We...