Matthew Breen

A Cytogenetically Characterized, Genome-Anchored 10-Mb BAC Set and CGH Array for the Domestic Dog (2007)

Thomas, Rachael, Duke, Shannon E., Bloom, Stephanie K., Breen, Tessa E., Young, Andrea C., Feiste, Erika, ...

The generation of a 7.5× dog genome assembly provides exciting new opportunities to interpret tumor-associated chromosome aberrations at the biological level. We present a genomic microarray for...

Construction of a 2-Mb resolution BAC microarray for CGH analysis of canine tumors (2005)

Thomas, Rachael, Scott, Allyson, Langford, Cordelia F., Fosmire, Susan P., Jubala, Cristan M., Lorentzen, Travis D., ...

Recognition of the domestic dog as a model for the comparative study of human genetic traits has led to major advances in canine genomics. The pathophysiological similarities shared between many...

An integrated 4249 marker FISH/RH map of the canine genome (2004)

Breen, Matthew, Hitte, Christophe, Lorentzen, Travis D, Thomas, Rachael, Cadieu, Edouard, Sabacan, Leah, ...

Abstract Background The 156 breeds of dog recognized by the American Kennel Club offer a unique opportunity to map genes important in genetic variation. Each breed features a defining constellation...

Comparison of regional gene expression differences in the brains of the domestic dog and human (2004)

Kennerly, Erin, Thomson, Susanne, Olby, Natasha, Breen, Matthew, Gibson, Greg

Comparison of the expression profiles of 2,721 genes in the cerebellum, cortex and pituitary gland of three American Staffordshire terriers, one beagle and one fox hound revealed regional expression...

A Mutation in the Canine BHD Gene is Associated with Hereditary Multifocal Renal Cystadenocarcinoma and Nodular Dermatofibrosis in the German Shepherd Dog (2003)

Lingaas, Frode, Comstock, Kenine E., Kirkness, Ewen F., Sørensen, Anita, Aarskaug, Tone, Hitte, Christophe, ...

Hereditary multifocal renal cystadenocarcinoma and nodular dermatofibrosis (RCND) is a naturally occurring canine kidney cancer syndrome that was originally described in German Shepherd dogs. The...

A mutation in the canine BHD gene is associated with hereditary multifocal renal cystadenocarcinoma and nodular dermatofibrosis in the German Shepherd dog (2003)

Lingaas, Frode, Comstock, Kenine E., Kirkness, Ewen F., Sørensen, Anita, Aarskaug, Tone, Hitte, Christophe, ...

Hereditary multifocal renal cystadenocarcinoma and nodular dermatofibrosis (RCND) is a naturally occurring canine kidney cancer syndrome that was originally described in German Shepherd dogs. The...

A Mutation in the Canine BHD Gene is Associated with Hereditary Multifocal Renal Cystadenocarcinoma and Nodular Dermatofibrosis in the German Shepherd Dog (2003)

Lingaas, Frode, Comstock, Kenine E., Kirkness, Ewen F., Sørensen, Anita, Aarskaug, Tone, Hitte, Christophe, ...

Hereditary multifocal renal cystadenocarcinoma and nodular dermatofibrosis (RCND) is a naturally occurring canine kidney cancer syndrome that was originally described in German Shepherd dogs. The...

Aniridia-associated cytogenetic rearrangements suggest that a position effect may cause the mutant phenotype (1995)

Fantes, Judy, Redeker, Bert, Breen, Matthew, Boyle, Shelagh, Brown, John, Fletcher, Judy, ...

Current evidence suggests that aniridia (absence of iris) is caused by loss of function of one copy of the PAX6 gene, which maps to 11p13. We present the further characterisation of two aniridia...

Chromosome studies in the Equidae. (1990)

Breen, Matthew.

Thesis (Ph. D.)--University of Liverpool, 1990.

A Primary Male Autosomal Linkage Map of the Horse Genome

Lindgren, Gabriella, Sandberg, Kaj, Persson, Helena, Marklund, Stefan, Breen, Matthew, Sandgren, Björn, ...

A primary male autosomal linkage map of the domestic horse (Equus caballus) has been developed by segregation analysis of 140 genetic markers within eight half-sib families. The family material...

Chromosome-Specific Single-Locus FISH Probes Allow Anchorage of an 1800-Marker Integrated Radiation-Hybrid/Linkage Map of the Domestic Dog Genome to All Chromosomes

Breen, Matthew, Jouquand, Sophie, Renier, Corinne, Mellersh, Cathryn S., Hitte, Christophe, Holmes, Nigel G., ...

We present here the first fully integrated, comprehensive map of the canine genome, incorporating detailed cytogenetic, radiation hybrid (RH), and meiotic information. We have mapped a collection of...

Genomic Organization of the Dog Dystroglycan Gene DAG1 Locus on Chromosome 20q15.1–q15.2

Leeb, Tosso, Neumann, Stephan, Deppe, Alexandra, Breen, Matthew, Brenig, Bertram

Dystroglycan is a laminin binding protein, which provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix. It is also involved in the organization of basement...

Construction of a 2-Mb resolution BAC microarray for CGH analysis of canine tumors

Thomas, Rachael, Scott, Allyson, Langford, Cordelia F., Fosmire, Susan P., Jubala, Cristan M., Lorentzen, Travis D., ...

Recognition of the domestic dog as a model for the comparative study of human genetic traits has led to major advances in canine genomics. The pathophysiological similarities shared between many...

Interleukin-12 Inhibits Tumor Growth in a Novel Angiogenesis Canine Hemangiosarcoma Xenograft Model1

Akhtar, Nasim, Padilla, Marcia L, Dickerson, Erin B, Steinberg, Howard, Breen, Matthew, Auerbach, Robert, ...

We established a canine hemangiosarcoma cell line derived from malignant endothelial cells comprising a spontaneous tumor in a dog to provide a renewable source of endothelial cells for studies of...

A Primary Male Autosomal Linkage Map of the Horse Genome

Lindgren, Gabriella, Sandberg, Kaj, Persson, Helena, Marklund, Stefan, Breen, Matthew, Sandgren, Björn, ...

A primary male autosomal linkage map of the domestic horse (Equus caballus) has been developed by segregation analysis of 140 genetic markers within eight half-sib families. The family material...

Chromosome-Specific Single-Locus FISH Probes Allow Anchorage of an 1800-Marker Integrated Radiation-Hybrid/Linkage Map of the Domestic Dog Genome to All Chromosomes

Breen, Matthew, Jouquand, Sophie, Renier, Corinne, Mellersh, Cathryn S., Hitte, Christophe, Holmes, Nigel G., ...

We present here the first fully integrated, comprehensive map of the canine genome, incorporating detailed cytogenetic, radiation hybrid (RH), and meiotic information. We have mapped a collection of...

Genomic Organization of the Dog Dystroglycan Gene DAG1 Locus on Chromosome 20q15.1–q15.2

Leeb, Tosso, Neumann, Stephan, Deppe, Alexandra, Breen, Matthew, Brenig, Bertram

Dystroglycan is a laminin binding protein, which provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix. It is also involved in the organization of basement...

Construction of a 2-Mb resolution BAC microarray for CGH analysis of canine tumors

Thomas, Rachael, Scott, Allyson, Langford, Cordelia F., Fosmire, Susan P., Jubala, Cristan M., Lorentzen, Travis D., ...

Recognition of the domestic dog as a model for the comparative study of human genetic traits has led to major advances in canine genomics. The pathophysiological similarities shared between many...

Interleukin-12 Inhibits Tumor Growth in a Novel Angiogenesis Canine Hemangiosarcoma Xenograft Model1

Akhtar, Nasim, Padilla, Marcia L, Dickerson, Erin B, Steinberg, Howard, Breen, Matthew, Auerbach, Robert, ...

We established a canine hemangiosarcoma cell line derived from malignant endothelial cells comprising a spontaneous tumor in a dog to provide a renewable source of endothelial cells for studies of...