Matthew W. McNatt

Direct Binding to Rsp5 Mediates Ubiquitin-independent Sorting of Sna3 via the Multivesicular Body Pathway

McNatt, Matthew W., McKittrick, Ian, West, Matthew, Odorizzi, Greg

The sorting of most integral membrane proteins into the lumenal vesicles of multivesicular bodies (MVBs) is dependent on the attachment of ubiquitin (Ub) to their cytosolic domains. However, Ub is...

Species-Specific Activity of HIV-1 Vpu and Positive Selection of Tetherin Transmembrane Domain Variants

McNatt, Matthew W., Zang, Trinity, Hatziioannou, Theodora, Bartlett, Mackenzie, Fofana, Ismael Ben, Johnson, Welkin E., ...

Tetherin/BST-2/CD317 is a recently identified antiviral protein that blocks the release of nascent retrovirus, and other virus, particles from infected cells. An HIV-1 accessory protein, Vpu, acts as...