Matthew W. Strobeck

Assessing the Impacts of the Prescription Drug User Fee Acts (PDUFA) on the FDA Approval Process (2005)

Berndt, Ernst R., Gottschalk, Adrian H. B., Philipson, Tomas, Strobeck, Matthew W.

Congress enacted and renewed the Prescription Drug User Fee Acts (PDUFA) in 1992, and renewed it in 1997 and 2002, mandating FDA performance goals in reviewing and acting on drug applications within...

Assessing the Impacts of the Prescription Drug User Fee Acts (PDUFA) on the FDA Approval Process (2005)

Berndt, Ernst R., Gottschalk, Adrian H. B., Philipson, Tomas, Strobeck, Matthew W.

Congress enacted and renewed the Prescription Drug User Fee Acts (PDUFA) in 1992, and renewed it in 1997 and 2002, mandating FDA performance goals in reviewing and acting on drug applications within...

Assessing the Impacts of the Prescription Drug User Fee Acts (PDUFA) on the FDA Approval Process (2005)

Berndt, Ernst R., Gottschalk, Adrian H. B., Philipson, Tomas, Strobeck, Matthew W.

Congress enacted and renewed the Prescription Drug User Fee Acts (PDUFA) in 1992, and renewed it in 1997 and 2002, mandating FDA performance goals in reviewing and acting on drug applications within...

Assessing the Impacts of the Prescription Drug User Fee Acts (PDUFA) on the FDA Approval Process (2005)

Berndt, Ernst R., Gottschalk, Adrian H. B., Philipson, Tomas, Strobeck, Matthew W.

Congress enacted and renewed the Prescription Drug User Fee Acts (PDUFA) in 1992, and renewed it in 1997 and 2002, mandating FDA performance goals in reviewing and acting on drug applications within...

Assessing the Impacts of the Prescription Drug User Fee Acts (PDUFA) on the FDA Approval Process

Ernst R. Berndt, Tomas Philipson, Matthew W. Strobeck

Congress enacted and renewed the Prescription Drug User Fee Acts (PDUFA) in 1992, and renewed it in 1997 and 2002, mandating FDA performance goals in reviewing and acting on drug applications within...

Assessing the Safety and Efficacy of the FDA: The Case of the Prescription Drug User Fee Acts

Tomas J. Philipson, Ernst R. Berndt, Matthew W. Strobeck

The US Food and drug Administration (FDA) is estimated to regulate markets accounting for about 20% of consumer spending in the US. This paper proposes a general methodology to evaluate FDA policies,...

Opportunities for Improving the Drug Development Process: Results from a Survey of Industry and the FDA

Ernst R. Berndt, Matthew W. Strobeck

In the United States, the Food and Drug Administration (FDA) agency is responsible for regulating the safety and efficacy of biopharmaceutical drug products. Furthermore, the FDA is tasked with...

BRG-1 is required for RB-mediated cell cycle arrest

Strobeck, Matthew W., Knudsen, Karen E., Fribourg, Anne F., DeCristofaro, Marc F., Weissman, Bernard E., Imbalzano, Anthony N., ...

The antiproliferative action of the retinoblastoma tumor suppressor protein, RB, is disrupted in the majority of human cancers. Disruption of RB activity occurs through several disparate mechanisms,...

BRG-1 is required for RB-mediated cell cycle arrest

Strobeck, Matthew W., Knudsen, Karen E., Fribourg, Anne F., DeCristofaro, Marc F., Weissman, Bernard E., Imbalzano, Anthony N., ...

The antiproliferative action of the retinoblastoma tumor suppressor protein, RB, is disrupted in the majority of human cancers. Disruption of RB activity occurs through several disparate mechanisms,...