Matthias Egger

Routine Vaccination Against Pertussis and the Risk of Childhood Asthma: A Population-Based Cohort Study (2009)

Spycher, Ben Daniel, Silverman, Michael, Egger, Matthias, Zwahlen, Marcel, Kuehni, Claudia Elisabeth

This paper was published as Pediatrics, 2009, 123 (3), pp. 944-950. It is available from http://pediatrics.aappublications.org/cgi/content/abstract/123/3/944. Doi: 10.1542/peds.2008-0115

Mortality of HIV-infected patients starting antiretroviral therapy in sub-Saharan Africa: comparison with HIV-unrelated mortality. (2009)

Brinkhof, Martin, Boulle, Andrew, Weigel, Ralf, Messou, Eugène, Mathers, Colin, Orrell, Catherine, ...

BACKGROUND: Mortality in HIV-infected patients who have access to highly active antiretroviral therapy (ART) has declined in sub-Saharan Africa, but it is unclear how mortality compares to the...

Mortality of HIV-infected patients starting antiretroviral therapy in sub-Saharan Africa: comparison with HIV-unrelated mortality. (2009)

Brinkhof, Martin, Boulle, Andrew, Weigel, Ralf, Messou, Eugène, Mathers, Colin, Orrell, Catherine, ...

BACKGROUND: Mortality in HIV-infected patients who have access to highly active antiretroviral therapy (ART) has declined in sub-Saharan Africa, but it is unclear how mortality compares to the...

Timing of initiation of antiretroviral therapy in AIDS-free HIV-1-infected patients: a collaborative analysis of 18 HIV cohort studies. (2009)

Sterne, Jonathan, May, Margaret, Costagliola, Dominique, De Wolf, Frank, Phillips, Andrew, Harris, Ross, ...

BACKGROUND: The CD4 cell count at which combination antiretroviral therapy should be started is a central, unresolved issue in the care of HIV-1-infected patients. In the absence of randomised...

Timing of initiation of antiretroviral therapy in AIDS-free HIV-1-infected patients: a collaborative analysis of 18 HIV cohort studies. (2009)

Sterne, Jonathan, May, Margaret, Costagliola, Dominique, De Wolf, Frank, Phillips, Andrew, Harris, Ross, ...

BACKGROUND: The CD4 cell count at which combination antiretroviral therapy should be started is a central, unresolved issue in the care of HIV-1-infected patients. In the absence of randomised...

Timing of initiation of antiretroviral therapy in AIDS-free HIV-1-infected patients: a collaborative analysis of 18 HIV cohort studies. (2009)

Sterne, Jonathan, May, Margaret, Costagliola, Dominique, De Wolf, Frank, Phillips, Andrew, Harris, Ross, ...

BACKGROUND: The CD4 cell count at which combination antiretroviral therapy should be started is a central, unresolved issue in the care of HIV-1-infected patients. In the absence of randomised...

Mortality of HIV-infected patients starting antiretroviral therapy in sub-Saharan Africa: comparison with HIV-unrelated mortality. (2009)

Brinkhof, Martin, Boulle, Andrew, Weigel, Ralf, Messou, Eugène, Mathers, Colin, Orrell, Catherine, ...

BACKGROUND: Mortality in HIV-infected patients who have access to highly active antiretroviral therapy (ART) has declined in sub-Saharan Africa, but it is unclear how mortality compares to the...

Residence Near Power Lines and Mortality From Neurodegenerative Diseases: Longitudinal Study of the Swiss Population (2009)

Huss, Anke, Spoerri, Adrian, Egger, Matthias, Röösli, Martin

The relation between residential magnetic field exposure from power lines and mortality from neurodegenerative conditions was analyzed among 4.7 million persons of the Swiss National Cohort (linking...

Cardiovascular mortality and exposure to extremely low frequency magnetic fields: a cohort study of Swiss railway workers (2008)

Röösli, Martin, Egger, Matthias, Pfluger, Dominik, Minder, Christoph

Abstract Background Exposure to intermittent magnetic fields of 16 Hz has been shown to reduce heart rate variability, and decreased heart rate variability predicts cardiovascular mortality. We...

Public-Health and Individual Approaches to Antiretroviral Therapy: Township South Africa and Switzerland Compared (2008)

Olivia Keiser, Catherine Orrell, Matthias Egger, Robin Wood, Hansjakob Furrer, ...

BackgroundThe provision of highly active antiretroviral therapy (HAART) in resource-limited settings follows a public health approach, which is characterised by a limited number of regimens and the...

Graphical presentation of diagnostic information (2008)

Whiting, Penny F, Sterne, Jonathan AC, Westwood, Marie E, Bachmann, Lucas M, Harbord, Roger, Egger, Matthias, ...

Abstract Background Graphical displays of results allow researchers to summarise and communicate the key findings of their study. Diagnostic information should be presented in an easily interpretable...

Early loss of HIV-infected patients on potent antiretroviral therapy programmes in lower-income countries. (2008)

Brinkhof, Martin, Dabis, François, Myer, Landon, Bangsberg, David, Boulle, Andrew, Nash, Denis, ...

OBJECTIVE: To analyse the early loss of patients to antiretroviral therapy (ART) programmes in resource-limited settings. METHODS: Using data on 5491 adult patients starting ART (median age 35 years,...

Early loss of HIV-infected patients on potent antiretroviral therapy programmes in lower-income countries. (2008)

Brinkhof, Martin, Dabis, François, Myer, Landon, Bangsberg, David, Boulle, Andrew, Nash, Denis, ...

OBJECTIVE: To analyse the early loss of patients to antiretroviral therapy (ART) programmes in resource-limited settings. METHODS: Using data on 5491 adult patients starting ART (median age 35 years,...

Declaración de la iniciativa Strobe (Strengthening the Reporting of Observational Studies in Epidemiology): Directrices para la comunicación de estudios observacionales (2008)

Altman, Douglas G., Egger, Matthias, Pocock, Stuart J., Gotzsche, Peter C., Vandenbroucke, Jan P., Von Elm, Erik

RESUMEN A pesar de que la mayor parte de la investigación biomédica es de tipo observacional, la información difundida sobre estas investigaciones es a menudo insuficiente, lo que dificulta la...

Early loss of HIV-infected patients on potent antiretroviral therapy programmes in lower-income countries. (2008)

Brinkhof, Martin, Dabis, François, Myer, Landon, Bangsberg, David, Boulle, Andrew, Nash, Denis, ...

OBJECTIVE: To analyse the early loss of patients to antiretroviral therapy (ART) programmes in resource-limited settings. METHODS: Using data on 5491 adult patients starting ART (median age 35 years,...

Promotion of health in older people: a randomised controlled trial of health risk appraisal in British general practice (2008)

Harari, Danielle, Iliffe, Steve, Kharicha, Kalpa, Egger, Matthias, Gillmann, Gerhard, ...

Background: there is inadequate evidence to support currently formulated NHS strategies to achieve health promotion and preventative care in older people through broad-based screening and assessment...

Childhood leukaemia and socioeconomic status: what is the evidence? (2008)

Adam, Martin, Rebholz, Cornelia E., Egger, Matthias, Zwahlen, Marcel, Kuehni, Claudia E.

The objectives of this systematic review are to summarise the current literature on socioeconomic status (SES) and the risk of childhood leukaemia, to highlight methodological problems and formulate...

What Do Case-Control Studies Estimate? Survey of Methods and Assumptions in Published Case-Control Research (2008)

Knol, Mirjam J., Vandenbroucke, Jan P., Scott, Pippa, Egger, Matthias

To evaluate strategies used to select cases and controls and how reported odds ratios are interpreted, the authors examined 150 case-control studies published in leading general medicine,...

Does short-term virologic failure translate to clinical events in antiretroviral-naïve patients initiating antiretroviral therapy in clinical practice? (2008)

Mugavero, Michael, May, Margaret, Harris, Ross, Saag, Michael, Costagliola, Dominique, Egger, Matthias, ...

OBJECTIVE: To determine whether differences in short-term virologic failure among commonly used antiretroviral therapy (ART) regimens translate to differences in clinical events in antiretroviral-na?...

Does short-term virologic failure translate to clinical events in antiretroviral-naïve patients initiating antiretroviral therapy in clinical practice? (2008)

Mugavero, Michael, May, Margaret, Harris, Ross, Saag, Michael, Costagliola, Dominique, Egger, Matthias, ...

OBJECTIVE: To determine whether differences in short-term virologic failure among commonly used antiretroviral therapy (ART) regimens translate to differences in clinical events in antiretroviral-na?...

Does short-term virologic failure translate to clinical events in antiretroviral-naïve patients initiating antiretroviral therapy in clinical practice? (2008)

Mugavero, Michael, May, Margaret, Harris, Ross, Saag, Michael, Costagliola, Dominique, Egger, Matthias, ...

OBJECTIVE: To determine whether differences in short-term virologic failure among commonly used antiretroviral therapy (ART) regimens translate to differences in clinical events in antiretroviral-na?...

BMC Medical Research Methodology BioMed Central Correspondence Graphical presentation of diagnostic information (2008)

Penny F Whiting, Jonathan Ac Sterne, Marie E Westwood, Lucas M Bachmann, Roger Harbord, Matthias Egger, ...

© 2008 Whiting et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License

Placebo-controlled trials of Chinese herbal medicine and conventional medicine comparative study (2007)

Shang, Aijing, Huwiler, Karin, Nartey, Linda, Jüni, Peter, Egger, Matthias

Background Chinese herbal medicine (CHM) is increasingly used in the West, but the evidence on its effectiveness is a matter of debate. We compared the characteristics, study quality and results of...

The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Statement: Guidelines for Reporting Observational Studies (2007)

Erik Von Elm, Douglas G. Altman, Matthias Egger, Stuart J. Pocock, Peter C. Gøtzsche, Jan P. Vandenbroucke

Much biomedical research is observational. The reporting of such research is often inadequate, which hampers the assessment of its strengths and weaknesses and of a study's generalisability. The...

Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): Explanation and Elaboration (2007)

Jan P. Vandenbroucke, Erik Von Elm, Douglas G. Altman, Peter C. Gøtzsche, Cynthia D. Mulrow, Stuart J. Pocock, ...

Much medical research is observational. The reporting of observational studies is often of insufficient quality. Poor reporting hampers the assessment of the strengths and weaknesses of a study and...

A unification of models for meta-analysis of diagnostic accuracy studies (2007)

Harbord, Roger M., Deeks, Jonathan J., Egger, Matthias, Whiting, Penny, Sterne, Jonathan A. C.

Studies of diagnostic accuracy require more sophisticated methods for their meta-analysis than studies of therapeutic interventions. A number of different, and apparently divergent, methods for...

Development, feasibility and performance of a health risk appraisal questionnaire for older persons (2007)

Stuck, Andreas E, Kharicha, Kalpa, Dapp, Ulrike, Anders, Jennifer, Meier-Baumgartner, Hans, ...

Abstract Background Health risk appraisal is a promising method for health promotion and prevention in older persons. The Health Risk Appraisal for the Elderly (HRA-E) developed in the U.S. has...

The PRO-AGE study: an international randomised controlled study of health risk appraisal for older persons based in general practice (2007)

Stuck, Andreas E, Kharicha, Kalpa, Dapp, Ulrike, Anders, Jennifer, Meier-Baumgartner, Hans, ...

Abstract Background This paper describes the study protocol, the recruitment, and base-line data for evaluating the success of randomisation of the PRO-AGE (PRevention in Older people – Assessment...

A coronary heart disease risk model for predicting the effect of potent antiretroviral therapy in HIV-1 infected men (2007)

May, Margaret, Sterne, Jonathan A C, Shipley, Martin, Brunner, Eric, D’Agostino, Ralph, Whincup, Peter, ...

Background Many HIV-infected patients on highly active antiretroviral therapy (HAART) experience metabolic complications including dyslipidaemia and insulin resistance, which may increase their...

A unification of models for meta-analysis of diagnostic accuracy studies (2007)

Harbord, Roger M., Deeks, Jonathan J., Egger, Matthias, Whiting, Penny, Sterne, Jonathan A. C.

Studies of diagnostic accuracy require more sophisticated methods for their meta-analysis than studies of therapeutic interventions. A number of different, and apparently divergent, methods for...

Correspondence to: (2006)

Marcel Zwahlen, Matthias Egger, Professor Matthias Egger

Progression and mortality of untreated HIV-positive individuals living in resource-limited settings: Update of literature review and evidence synthesis

A unification of models for meta-analysis of diagnostic accuracy studies (2006)

Harbord, Roger M., Deeks, Jonathan J., Egger, Matthias, Whiting, Penny, Sterne, Jonathan A.C.

Studies of diagnostic accuracy require more sophisticated methods for their meta-analysis than studies of therapeutic interventions. A number of different, and apparently divergent, methods for...

Years of life lost attributable to air pollution in Switzerland: dynamic exposure-response model (2005)

Röösli, Martin, Künzli, Nino, Braun-Fahrländer, Charlotte, Egger, Matthias

Background There is debate on how the effect of air pollution should be assessed. We propose an approach to estimate its impact on adult and infant mortality that integrates data from long-term...

Years of life lost attributable to air pollution in Switzerland: dynamic exposure-response model (2005)

Röösli, Martin, Künzli, Nino, Braun-Fahrländer, Charlotte, Egger, Matthias

Background There is debate on how the effect of air pollution should be assessed. We propose an approach to estimate its impact on adult and infant mortality that integrates data from long-term...

Risk factors for asymptomatic abdominal aortic aneurysm: Systematic review and meta-analysis of population-based screening studies (2004)

Cornuz, Jacques, Sidoti Pinto, Claudio, Tevaearai, Heindrik, Egger, Matthias

Background: The incidence of and mortality from ruptured abdominal aortic aneurysm (AAA) is increasing. There is uncertainty regarding the indicators which could be used to identify groups at high...

Women's perception of the benefits of mammography screening: population-based survey in four countries (2003)

Domenighetti, Gianfranco, D’Avanzo, Barbara, Egger, Matthias, Berrino, Franco, Perneger, Thomas, Mosconi, Paola, ...

Background Screening programmes are often actively promoted to achieve high coverage, which may result in unrealistic expectations. We examined women’s understanding of the likely benefits of...

Direction and impact of language bias in meta-analyses of controlled trials: empirical study (2002)

Jüni, Peter, Holenstein, Franziska, Sterne, Jonathan, Bartlett, Christopher, Egger, Matthias

Background Excluding clinical trials reported in languages other than English from meta-analyses may introduce bias and reduce the precision of combined estimates of treatment effects. We examined...

Effekt von Biperiden auf den Morgenschlaf nach Schlafentzug bei Gesunden [microform] / (1999)

Egger, Matthias.

Thesis (doctoral)--Albert-Ludwigs-Universität Freiburg im Breisgau, 1999.

Post-Challenge Glucose Concentration, Impaired Glucose Tolerance, Diabetes, and Cancer Mortality in Men (1992)

Smith, George Davey, Egger, Matthias, Shipley, Martin J., Marmot, M. G.

The possibility that diabetes is associated with an elevated risk of cancer mortality has been discussed for many years. Recently, Levine et al. (Am J Epidemiol, 1990; 131: 254–62) approached this...

Screening for chlamydial infections and the risk of ectopic pregnancy in a county in Sweden: ecological analysis

Egger, Matthias, Low, Nicola, Smith, George Davey, Lindblom, Bo, Herrmann, Björn

Objectives: To analyse trends in rates of genital chlamydial infection and ectopic pregnancy between 1985 and 1995 in a county in Sweden.

Clinical efficacy of antiretroviral combination therapy based on protease inhibitors or non-nucleoside analogue reverse transcriptase inhibitors: indirect comparison of controlled trials

Yazdanpanah, Yazdan, Sissoko, Daouda, Egger, Matthias, Mouton, Yves, Zwahlen, Marcel, Chêne, Geneviève

Objective To compare the clinical efficacy of triple antiretroviral regimens based on protease inhibitors and non-nucleoside analogue reverse transcriptase inhibitors (NNRTIs) in adults positive for...

Coverage and uptake of systematic postal screening for genital Chlamydia trachomatis and prevalence of infection in the United Kingdom general population: cross sectional study

Macleod, John, Salisbury, Chris, Low, Nicola, McCarthy, Anne, Sterne, Jonathan A C, Holloway, Aisha, ...

Objective To measure the coverage and uptake of systematic postal screening for genital Chlamydia trachomatis and the prevalence of infection in the general population in the United Kingdom. To...

Enhanced Enzyme Immunoassay with Negative-Gray-Zone Testing Compared to a Single Nucleic Acid Amplification Technique for Community-Based Chlamydial Screening of Men

Horner, Paddy, Skidmore, Sue, Herring, Alan, Sell, Jo, Paul, Ian, Caul, Owen, ...

We evaluated a low-cost diagnostic strategy for detecting Chlamydia trachomatis in a low-prevalence population. We used an amplified enzyme immunoassay (EIA) with a reduced-cutoff “negative gray...

Partner notification of chlamydia infection in primary care: randomised controlled trial and analysis of resource use

Low, Nicola, McCarthy, Anne, Roberts, Tracy E, Huengsberg, Mia, Sanford, Emma, Sterne, Jonathan A C, ...

Objective To evaluate the effectiveness of a practice nurse led strategy to improve the notification and treatment of partners of people with chlamydia infection.

Impact of Helicobacter pylori eradication on dyspepsia, health resource use, and quality of life in the Bristol helicobacter project: randomised controlled trial

Lane, J Athene, Murray, Liam J, Noble, Sian, Egger, Matthias, Harvey, Ian M, Donovan, Jenny L, ...

Objective To determine the impact of a community based Helicobacter pylori screening and eradication programme on the incidence of dyspepsia, resource use, and quality of life, including a cost...

Accuracy of magnetic resonance imaging for the diagnosis of multiple sclerosis: systematic review

Whiting, Penny, Harbord, Roger, Main, Caroline, Deeks, Jonathan J, Filippini, Graziella, Egger, Matthias, ...

Objective To determine the accuracy of magnetic resonance imaging criteria for the early diagnosis of multiple sclerosis in patients with suspected disease.

Screening for chlamydial infections and the risk of ectopic pregnancy in a county in Sweden: ecological analysis

Egger, Matthias, Low, Nicola, Smith, George Davey, Lindblom, Bo, Herrmann, Björn

Objectives: To analyse trends in rates of genital chlamydial infection and ectopic pregnancy between 1985 and 1995 in a county in Sweden.

Clinical efficacy of antiretroviral combination therapy based on protease inhibitors or non-nucleoside analogue reverse transcriptase inhibitors: indirect comparison of controlled trials

Yazdanpanah, Yazdan, Sissoko, Daouda, Egger, Matthias, Mouton, Yves, Zwahlen, Marcel, Chêne, Geneviève

Objective To compare the clinical efficacy of triple antiretroviral regimens based on protease inhibitors and non-nucleoside analogue reverse transcriptase inhibitors (NNRTIs) in adults positive for...

Coverage and uptake of systematic postal screening for genital Chlamydia trachomatis and prevalence of infection in the United Kingdom general population: cross sectional study

Macleod, John, Salisbury, Chris, Low, Nicola, McCarthy, Anne, Sterne, Jonathan A C, Holloway, Aisha, ...

Objective To measure the coverage and uptake of systematic postal screening for genital Chlamydia trachomatis and the prevalence of infection in the general population in the United Kingdom. To...

Enhanced Enzyme Immunoassay with Negative-Gray-Zone Testing Compared to a Single Nucleic Acid Amplification Technique for Community-Based Chlamydial Screening of Men

Horner, Paddy, Skidmore, Sue, Herring, Alan, Sell, Jo, Paul, Ian, Caul, Owen, ...

We evaluated a low-cost diagnostic strategy for detecting Chlamydia trachomatis in a low-prevalence population. We used an amplified enzyme immunoassay (EIA) with a reduced-cutoff “negative gray...

Partner notification of chlamydia infection in primary care: randomised controlled trial and analysis of resource use

Low, Nicola, McCarthy, Anne, Roberts, Tracy E, Huengsberg, Mia, Sanford, Emma, Sterne, Jonathan A C, ...

Objective To evaluate the effectiveness of a practice nurse led strategy to improve the notification and treatment of partners of people with chlamydia infection.

Impact of Helicobacter pylori eradication on dyspepsia, health resource use, and quality of life in the Bristol helicobacter project: randomised controlled trial

Lane, J Athene, Murray, Liam J, Noble, Sian, Egger, Matthias, Harvey, Ian M, Donovan, Jenny L, ...

Objective To determine the impact of a community based Helicobacter pylori screening and eradication programme on the incidence of dyspepsia, resource use, and quality of life, including a cost...

Accuracy of magnetic resonance imaging for the diagnosis of multiple sclerosis: systematic review

Whiting, Penny, Harbord, Roger, Main, Caroline, Deeks, Jonathan J, Filippini, Graziella, Egger, Matthias, ...

Objective To determine the accuracy of magnetic resonance imaging criteria for the early diagnosis of multiple sclerosis in patients with suspected disease.

Vulvovaginal-Swab or First-Catch Urine Specimen To Detect Chlamydia trachomatis in Women in a Community Setting?▿

Skidmore, Sue, Horner, Paddy, Herring, Alan, Sell, Joanne, Paul, Ian, Thomas, Jane, ...

Screening for chlamydia in women is widely recommended. We evaluated the performance of two nucleic acid amplification tests for detecting Chlamydia trachomatis in self-collected vulvovaginal-swab...

Cost effectiveness of home based population screening for Chlamydia trachomatis in the UK: economic evaluation of chlamydia screening studies (ClaSS) project

Roberts, Tracy E, Robinson, Suzanne, Barton, Pelham M, Bryan, Stirling, McCarthy, Anne, Macleod, John, ...

Objective To investigate the cost effectiveness of screening for Chlamydia trachomatis compared with a policy of no organised screening in the United Kingdom.

Accuracy of electrocardiography in diagnosis of left ventricular hypertrophy in arterial hypertension: systematic review

Pewsner, Daniel, Jüni, Peter, Egger, Matthias, Battaglia, Markus, Sundström, Johan, Bachmann, Lucas M

Objective To review the accuracy of electrocardiography in screening for left ventricular hypertrophy in patients with hypertension.

Strengthening the reporting of observational studies in epidemiology (STROBE) statement: guidelines for reporting observational studies

Von Elm, Erik, Altman, Douglas G, Egger, Matthias, Pocock, Stuart J, Gøtzsche, Peter C, Vandenbroucke, Jan P

Poor reporting of research hampers assessment and makes it less useful. An international group of methodologists, researchers, and journal editors sets out guidelines to improve reports of...

The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Statement: Guidelines for Reporting Observational Studies

Von Elm, Erik, Altman, Douglas G, Egger, Matthias, Pocock, Stuart J, Gøtzsche, Peter C, Vandenbroucke, Jan P

This paper describes the recommendations of The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Initiative on what should be included in an accurate and complete report...

Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): Explanation and Elaboration

Vandenbroucke, Jan P, Von Elm, Erik, Altman, Douglas G, Gøtzsche, Peter C, Mulrow, Cynthia D, Pocock, Stuart J, ...

In this explanatory and elaboration document Mattias Egger and colleagues provide the meaning and rationale of each checklist item on the STROBE Statement.

Empirical evidence of bias in treatment effect estimates in controlled trials with different interventions and outcomes: meta-epidemiological study

Wood, Lesley, Egger, Matthias, Gluud, Lise Lotte, Schulz, Kenneth F, Jüni, Peter, Altman, Douglas G, ...

Objective To examine whether the association of inadequate or unclear allocation concealment and lack of blinding with biased estimates of intervention effects varies with the nature of the...

Public-Health and Individual Approaches to Antiretroviral Therapy: Township South Africa and Switzerland Compared

Keiser, Olivia, Orrell, Catherine, Egger, Matthias, Wood, Robin, Brinkhof, Martin W. G, Furrer, Hansjakob, ...

Comparing HIV treatment in Switzerland, where drug selection is individualized, and South Africa, where a programmatic approach is used, Matthias Egger and colleagues find similar virologic outcomes...

Mortality of HIV-Infected Patients Starting Antiretroviral Therapy in Sub-Saharan Africa: Comparison with HIV-Unrelated Mortality

Brinkhof, Martin W. G., Boulle, Andrew, Weigel, Ralf, Messou, Eugène, Mathers, Colin, Orrell, Catherine, ...

Comparing mortality rates between patients starting HIV treatment and the general population in four African countries, Matthias Egger and colleagues find the gap decreases over time, especially with...

The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Statement: guidelines for reporting observational studies*

Von Elm, Erik, Altman, Douglas G, Egger, Matthias, Pocock, Stuart J, Gøtzsche, Peter C, Vandenbroucke, Jan P

Much biomedical research is observational. The reporting of such research is often inadequate, which hampers the assessment of its strengths and weaknesses and of a study’s generalizability. The...