Matthias Ochs

Exogenous surfactant application in a rat lung ischemia reperfusion injury model: effects on edema formation and alveolar type II cells (2008)

Dreyer, Niels, Mühlfeld, Christian, Fehrenbach, Antonia, Pech, Thomas, Von Berg, Sebastian, Nagib, Ragi, ...

Abstract Background Prophylactic exogenous surfactant therapy is a promising way to attenuate the ischemia and reperfusion (I/R) injury associated with lung transplantation and thereby to decrease...

Exogenous surfactant application in a rat lung ischemia reperfusion injury model: effects on edema formation and alveolar type II cells ; Research (2008)

Dreyer, Niels, Mühlfeld, Christian, Fehrenbach, Antonia, Pech, Thomas, Berg, Sebastian Von, Nagib, Ragi, ...

Background: Prophylactic exogenous surfactant therapy is a promising way to attenuate the ischemia and reperfusion (I/R) injury associated with lung transplantation and thereby to decrease the...

Visualization and quantitative analysis of nanoparticles in the respiratory tract by transmission electron microscopy (2007)

Mühlfeld, Christian, Rothen-Rutishauser, Barbara, Vanhecke, Dimitri, Blank, Fabian, Gehr, Peter, Ochs, Matthias

Abstract Nanotechnology in its widest sense seeks to exploit the special biophysical and chemical properties of materials at the nanoscale. While the potential technological, diagnostic or...

Truncated recombinant human SP-D attenuates emphysema and type II cell changes in SP-D deficient mice (2007)

Knudsen, Lars, Ochs, Matthias, MacKay, Rosemarie, Townsend, Paul, Deb, Roona, Mühlfeld, Christian, ...

Abstract Background Surfactant protein D (SP-D) deficient mice develop emphysema-like pathology associated with focal accumulations of foamy alveolar macrophages, an excess of surfactant...

Truncated recombinant human SP-D attenuates emphysema and type II cell changes in SP-D deficient mice (2007)

Knudsen, Lars, Ochs, Matthias, Mackay, Rosemarie, Townsend, Paul, Deb, Roona, Mühlfeld, Christian, ...

BACKGROUND: Surfactant protein D (SP-D) deficient mice develop emphysema-like pathology associated with focal accumulations of foamy alveolar macrophages, an excess of surfactant phospholipids in the...

Implications of dealing with airborne substances and reactive oxygen species: what mammalian lungs, animals, and plants have to say? (2007)

Spinelli Oliveira, Elisabeth, Hancock, John T., Hermes-Lima, Marcelo, Isola, Daniel A., Ochs, Matthias, Yu, Jerry, ...

A gas-exchange structure interacts with the environment and is constantly challenged by contaminants that may elicit defense responses, thus compromising its primary function. It is also exposed to...

Alterations of alveolar type II cells and intraalveolar surfactant after bronchoalveolar lavage and perfluorocarbon ventilation. An electron microscopical and stereological study in the rat lung (2007)

Rüdiger, Mario, Wendt, Sebastian, Köthe, Lars, Burkhardt, Wolfram, Wauer, Roland R, Ochs, Matthias

Abstract Background Repeated bronchoalveolar lavage (BAL) has been used in animals to induce surfactant depletion and to study therapeutical interventions of subsequent respiratory insufficiency....

Truncated recombinant human SP-D attenuates emphysema and type II cell changes in SP-D deficient mice ; Research (2007)

Knudsen, Lars, Ochs, Matthias, MacKay, Rosemarie, Townsend, Paul, Deb, Roona, Mühlfeld, Christian, ...

Background: Surfactant protein D (SP-D) deficient mice develop emphysema-like pathology associated with focal accumulations of foamy alveolar macrophages, an excess of surfactant phospholipids in the...

Counterpoint: Chronic Hypoxia-induced Pulmonary Hypertension does not Lead to Loss of Pulmonary Vasculature (2007)

Ewald R. Weibel, Matthias Ochs, N. Regamey, M. Ochs, ...

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Morphological alterations of exogenous surfactant inhibited by meconium can be prevented by dextran (2006)

Ochs, Matthias, Schüttler, Markus, Stichtenoth, Guido, Herting, Egbert

Abstract Background Surfactant dysfunction due to inhibition is involved in the pathophysiology of meconium aspiration syndrome. Dextran addition has been shown to reverse exogenous surfactant...

Improved lung preservation relates to an increase in tubular myelin-associated surfactant protein A (2005)

Fehrenbach, Heinz, Tews, Sebastian, Fehrenbach, Antonia, Ochs, Matthias, Wittwer, Thorsten, Wahlers, Thorsten, ...

Abstract Background Declining levels of surfactant protein A (SP-A) after lung transplantation are suggested to indicate progression of ischemia/reperfusion (IR) injury. We hypothesized that the...

Improved lung preservation relates to an increase in tubular myelin-associated surfactant protein ; Research (2005)

Fehrenbach, A. Heinz, Tews, Sebastian, Fehrenbach, Antonia, Ochs, Matthias, Wittwer, Thorsten, Wahlers, Thorsten, ...

Background: Declining levels of surfactant protein A (SP-A) after lung transplantation are suggested to indicate progression of ischemia/reperfusion (IR) injury. We hypothesized that the previously...

Disruption of an inner arm dynein heavy chain gene results in asthenozoospermia and reduced ciliary beat frequency (2001)

Neesen, Juergen, Kirschner, Renate, Ochs, Matthias, Schmiedl, Andreas, Habermann, Barbara, Mueller, Christian, ...

Impaired ciliary and flagellar functions resulting in male infertility and recurrent respiratory tract infections are found in patients suffering from primary ciliary dyskinesia (PCD). In most cases,...

Sox15 Is Required for Skeletal Muscle Regeneration

Lee, Heon-Jin, Göring, Wolfgang, Ochs, Matthias, Mühlfeld, Christian, Steding, Gerd, Paprotta, Ilona, ...

The Sox genes define a family of transcription factors that play a key role in the determination of cell fate during development. The preferential expression of the Sox15 in the myogenic precursor...

To what extent are the retinal capillaries ensheathed by Müller cells? A stereological study in the tree shrew Tupaia belangeri

OCHS, MATTHIAS, MAYHEW, TERRY M., KNABE, WOLFGANG

The cellular ensheathment of capillaries in the 3 outer capillary layers of the central retina of the adult tree shrew Tupaia belangeri was studied quantitatively by transmission electron microscopy....

Sox15 Is Required for Skeletal Muscle Regeneration

Lee, Heon-Jin, Göring, Wolfgang, Ochs, Matthias, Mühlfeld, Christian, Steding, Gerd, Paprotta, Ilona, ...

The Sox genes define a family of transcription factors that play a key role in the determination of cell fate during development. The preferential expression of the Sox15 in the myogenic precursor...

To what extent are the retinal capillaries ensheathed by Müller cells? A stereological study in the tree shrew Tupaia belangeri

OCHS, MATTHIAS, MAYHEW, TERRY M., KNABE, WOLFGANG

The cellular ensheathment of capillaries in the 3 outer capillary layers of the central retina of the adult tree shrew Tupaia belangeri was studied quantitatively by transmission electron microscopy....

Visualization and quantitative analysis of nanoparticles in the respiratory tract by transmission electron microscopy

Mühlfeld, Christian, Rothen-Rutishauser, Barbara, Vanhecke, Dimitri, Blank, Fabian, Gehr, Peter, Ochs, Matthias

Nanotechnology in its widest sense seeks to exploit the special biophysical and chemical properties of materials at the nanoscale. While the potential technological, diagnostic or therapeutic...