Maxine F. Singer

Genomic organization of low copy number sequences that are associated with deca-satellite DNA in the monkey genome (1987)

Maresca, Antonella, Thayer, Ronald E., Gosselin, Pierre, Singer, Maxine F.

A previously described segment of African green monkey DNA (cloned in phage λMkA) contains deca-satellite linked to DNA sequences that are estimated to occur once per genome. Sequences homologous to...

Analysis of LINE-1 family sequences on a single monkey chromosome (1986)

Lee, Theresa N. H., Singer, Maxine F.

The structure of LINE-1 (LICa) family members present on African green monkey chromosome CAE-19 is compared with that of the entire set of LICa sequences present in the monkey genome.The analysis...

Transcription from SV40-like monkey DNA sequences (1984)

Saffer, Jeffrey D., Singer, Maxine F.

The ability of an African green monkey genomic segment, homologous to the regulatory region of SV40, to promote transcription in monkey cells has been investigated. Genomic transcripts from CV-1...

Homology between the KpnI primate and BamHI (M1F-1) rodent families of long interspersed repeated sequences (1983)

Singer, Maxine F., Thayer, Ronald E., Grimaldi, Giovanna, Lennan, Michael I., Fanning, Thomas G.

The Kpnl and BamHl (or M1F-1) families are the predominant sets of long interspersed repeated DNA sequences (LINEs) in primates and rodents, respectively. Recently, the sequences of several cloned...

Sequence relationships between single repeat units of highly reiterated African Green monkey DNA (1981)

Thayer, Ronald E., Singer, Maxine F., McCutchan, Thomas F.

Individual monomer and dimer units of the highly repeated α-component DNA of African Green monkeys were isolated and amplified by molecular cloning in pBR322. The purified sequences were...

Interspersed repeated sequences in the African green monkey genome that are homologous to the human Alu family (1981)

Grimaldi, Giovanna, Queen, Cary, Singer, Maxine F.

The dominant family of interspersed repetitive DNA sequences in the human genome has been termed the Alu family. We have found that more than 75% of the λ phage in a recombinant library representing...

The effect of H1 histone on the action of DNA-relaxing enzyme (1977)

Bina-Stein, Minou, Singer, Maxine F.

The action of DNA-relaxing enzyme on Hl-ENA complexes was investigated. Complexes of superhelical and relaxed closed circular duplex DNA with H1 were treated with mammalian relaxing enzyme,...

Histone synthesis during infection of monkey kidney cells with Simian Virus 40 (1977)

Kay, Alan C., Singer, Maxine F.

The synthesis of histones during lytic infection of BSC-1 (African Green Monkey kidney) cells with SV40 has been investigated. The synthesis of all five classes of histones was stimulated, and all...

Studies on the interaction of H1 histone with superhelical DNA: Characterization of the recognition and binding regions of H1 histone (1976)

Singer, Dinah S., Singer, Maxine F.

The very lysine rich histone, Hl, isolated from a variety of sources interacts preferentially with superhelical DNA compared to relaxed DNA duplexes13. The nature of this specific interaction has...

Summary statement of the Asilomar conference on recombinant DNA molecules (1975)

Berg, Paul, Baltimore, David, Brenner, Sydney, Singer, Maxine F.

This meeting was organized to review scientific progress in research on recombinant DNA molecules and to discuss appropriate ways to deal with the potential biohazards of this work. Impressive...

Further characterization of the polynucleotide phosphorylase of Micrococcus luteus (1975)

Letendre, Carol H., Singer, Maxine F.

The purification of polynucleotide phosphorylase from Micrococcus luteus by chromatography on phosphocellulose columns is described. This procedure offers several advantages over previous procedures....

Further characterization of the polynucleotide phosphorylase of Micrococcus luteus

Letendre, Carol H., Singer, Maxine F.

The purification of polynucleotide phosphorylase from Micrococcus luteus by chromatography on phosphocellulose columns is described. This procedure offers several advantages over previous procedures.

Acquisition of Sequences Homologous to Host DNA by Closed Circular Simian Virus 40 DNA II. Further Studies on the Serial Passage of Virus Clones

Lavi, Sara, Rozenblatt, Shmuel, Singer, Maxine F., Winocour, Ernest

Three plaque isolates of SV40 strain 777 and 1 plaque isolate of strain 776 were grown to high-titer stocks and serially passaged, undiluted, in monkey BS-C-1 cells. In each case, the serial...

Acquisition of Sequences Homologous to Host DNA by Closed Circular Simian Virus 40 DNA III. Host Sequences

Rozenblatt, Shmuel, Lavi, Sara, Singer, Maxine F., Winocour, Ernest

A preparation of serially passaged simian virus 40 (SV40) DNA, in which at least 66% of the molecules contain covalently linked cellular DNA sequences, was digested to completion with the Hemophilus...

Localization of Replicating DNA of Simian Virus 40 in Monkey Kidney Cells

LeBlanc, Donald J., Singer, Maxine F.

Approximately 80-85% of the DNA synthesized by cells infected with simian virus 40 during a short pulse with [3H]thymidine is associated with host nuclear membrane components, as defined by the...

Further characterization of the polynucleotide phosphorylase of Micrococcus luteus

Letendre, Carol H., Singer, Maxine F.

The purification of polynucleotide phosphorylase from Micrococcus luteus by chromatography on phosphocellulose columns is described. This procedure offers several advantages over previous procedures.

Acquisition of Sequences Homologous to Host DNA by Closed Circular Simian Virus 40 DNA II. Further Studies on the Serial Passage of Virus Clones

Lavi, Sara, Rozenblatt, Shmuel, Singer, Maxine F., Winocour, Ernest

Three plaque isolates of SV40 strain 777 and 1 plaque isolate of strain 776 were grown to high-titer stocks and serially passaged, undiluted, in monkey BS-C-1 cells. In each case, the serial...

Acquisition of Sequences Homologous to Host DNA by Closed Circular Simian Virus 40 DNA III. Host Sequences

Rozenblatt, Shmuel, Lavi, Sara, Singer, Maxine F., Winocour, Ernest

A preparation of serially passaged simian virus 40 (SV40) DNA, in which at least 66% of the molecules contain covalently linked cellular DNA sequences, was digested to completion with the Hemophilus...

Localization of Replicating DNA of Simian Virus 40 in Monkey Kidney Cells

LeBlanc, Donald J., Singer, Maxine F.

Approximately 80-85% of the DNA synthesized by cells infected with simian virus 40 during a short pulse with [3H]thymidine is associated with host nuclear membrane components, as defined by the...