Mayda Gursel

Potential Role of Phosphatidylinositol 3 Kinase, rather than DNA-dependent Protein Kinase, in CpG DNA–induced Immune Activation

Ishii, Ken J., Takeshita, Fumihiko, Gursel, Ihsan, Gursel, Mayda, Conover, Jacqueline, Nussenzweig, Andre, ...

Unmethylated CpG motifs present in bacterial DNA stimulate a strong innate immune response. There is evidence that DNA-dependent protein kinase (DNA-PK) mediates CpG signaling. Specifically,...