Megan E. Keniry

Genetic Dissection of PTEN Signaling Mechanisms in Prostate Cancer (1998)

Keniry, Megan E., Hannon, Greg, Parsons, Ramon

The goal of my traineeship is to employ genetic approaches to investigate PTEN signaling in prostate cancer. My first task was to construct expression vectors for a series of tumor-derived PTEN...

Identification of p21-Activated Kinase Specificity Determinants in Budding Yeast: a Single Amino Acid Substitution Imparts Ste20 Specificity to Cla4

Keniry, Megan E., Sprague, Jr., George F.

Two closely related p21-activated kinases from Saccharomyces cerevisiae, Ste20 and Cla4, interact with and are regulated by Cdc42, a small Rho-like GTPase. These kinases are argued to perform a...

Synthetic Lethal Analysis Implicates Ste20p, a p21-activated Protein Kinase, in Polarisome ActivationD⃞

Goehring, April S., Mitchell, David A., Tong, Amy Hin Yan, Keniry, Megan E., Boone, Charles, Sprague, George F.

The p21-activated kinases Ste20p and Cla4p carry out undefined functions that are essential for viability during budding in Saccharomyces cerevisiae. To gain insight into the roles of Ste20p, we have...

The identification of Pcl1-interacting proteins that genetically interact with Cla4 may indicate a link between G1 progression and mitotic exit.

Keniry, Megan E, Kemp, Hilary A, Rivers, David M, Sprague, George F

In budding yeast, Cla4 and Ste20, two p21-activated kinases, contribute to numerous morphogenetic processes. Loss of Ste20 or Cla4 individually confers distinct phenotypes, implying that they...

Identification of p21-Activated Kinase Specificity Determinants in Budding Yeast: a Single Amino Acid Substitution Imparts Ste20 Specificity to Cla4

Keniry, Megan E., Sprague, Jr., George F.

Two closely related p21-activated kinases from Saccharomyces cerevisiae, Ste20 and Cla4, interact with and are regulated by Cdc42, a small Rho-like GTPase. These kinases are argued to perform a...

Synthetic Lethal Analysis Implicates Ste20p, a p21-activated Protein Kinase, in Polarisome ActivationD⃞

Goehring, April S., Mitchell, David A., Tong, Amy Hin Yan, Keniry, Megan E., Boone, Charles, Sprague, George F.

The p21-activated kinases Ste20p and Cla4p carry out undefined functions that are essential for viability during budding in Saccharomyces cerevisiae. To gain insight into the roles of Ste20p, we have...

The identification of Pcl1-interacting proteins that genetically interact with Cla4 may indicate a link between G1 progression and mitotic exit.

Keniry, Megan E, Kemp, Hilary A, Rivers, David M, Sprague, George F

In budding yeast, Cla4 and Ste20, two p21-activated kinases, contribute to numerous morphogenetic processes. Loss of Ste20 or Cla4 individually confers distinct phenotypes, implying that they...