Megan M. Durham

Heterologous immunity provides a potent barrier to transplantation tolerance

Adams, Andrew B., Williams, Matthew A., Jones, Thomas R., Shirasugi, Nozomu, Durham, Megan M., Kaech, Susan M., ...

Many strategies have been proposed to induce tolerance to transplanted tissue in rodents; however, few if any have shown equal efficacy when tested in nonhuman primate transplant models. We...

Asialo GM1+ CD8+ T cells play a critical role in costimulation blockade–resistant allograft rejection

Trambley, Joel, Bingaman, Adam W., Lin, Angello, Elwood, Eric T., Waitze, Seung-Yeun, Ha, Jongwon, ...

Simultaneous blockade of the CD40 and CD28 costimulatory pathways is an effective treatment strategy to promote allograft acceptance but does not lead to indefinite allograft survival. The immune...

Heterologous immunity provides a potent barrier to transplantation tolerance

Adams, Andrew B., Williams, Matthew A., Jones, Thomas R., Shirasugi, Nozomu, Durham, Megan M., Kaech, Susan M., ...

Many strategies have been proposed to induce tolerance to transplanted tissue in rodents; however, few if any have shown equal efficacy when tested in nonhuman primate transplant models. We...

Asialo GM1+ CD8+ T cells play a critical role in costimulation blockade–resistant allograft rejection

Trambley, Joel, Bingaman, Adam W., Lin, Angello, Elwood, Eric T., Waitze, Seung-Yeun, Ha, Jongwon, ...

Simultaneous blockade of the CD40 and CD28 costimulatory pathways is an effective treatment strategy to promote allograft acceptance but does not lead to indefinite allograft survival. The immune...