Meng Wang

Prize-Collecting Data Fusion for Cost-Performance Tradeoff in Distributed Inference (2009)

Animashree An, Meng Wang, Lang Tong, Ananthram Swami

Abstract—A novel formulation for optimal sensor selection and in-network fusion for distributed inference known as the prizecollecting data fusion (PCDF) is proposed in terms of optimal tradeoff...

Extremal Random Walks on Trees (2009)

Wang, Meng

We study random walks on trees, where we iteratively move from one vertex to a randomly chosen adjacent vertex. We study two quantities arising in random walks: the hitting time and the mixing time....

On the Pursuit of Static and Coherent Weaving (2009)

Meng Wang

Aspect-oriented programming (AOP) has been shown to be a useful model for software development. Special care must be taken when we try to adapt AOP to strongly typed functional languages which come...

Particokinetics and Extrapulmonary Translocation of Intratracheally Instilled Ferric Oxide Nanoparticles in Rats and the Potential Health Risk Assessment (2009)

Zhu, Mo-Tao, Feng, Wei-Yue, Wang, Yun, Wang, Bing, Wang, Meng, Ouyang, Hong, ...

Exposure to nanoparticles has presented potential risks to human cardiorespiratory systems. Pulmonary retention and extrapulmonary redistribution of inhaled nanoparticles have been considered to be...

Prize-Collecting Data Fusion for Cost-Performance Tradeoff (2009)

Animashree An, Meng Wang, Lang Tong, Ananthram Swami

A novel formulation for optimal sensor selection and in-network fusion for distributed inference known as the prize-collecting data fusion (PCDF) is proposed in terms of optimal tradeoff between the...

An Algorithm for V/UV/S Segmentation of Speech by (2008)

Meng Wang, Donald Bitzer, David Mcallister, Robert Rodman, Jamie Taylor

Let f(n) be a sampled voice signal. Our goal is to identify the voiced (V) portions of f (as opposed to the silence (S) and unvoiced (UV) portions). In the following discussion, the sampling rate is...

Real-Time Loop Scheduling with Leakage Energy Minimization for Embedded VLIW DSP Processors £Ý (2008)

Meng Wang, Zili Shao

In this paper, we develop a novel real-time instructionlevel loop scheduling technique to reduce leakage energy consumption for applications with loops on VLIW architecture. We first prove that the...

REALM: A Loop Memory Access Optimization Technique with Loop-Carried Data Dependence Analysis for DSP Applications (2008)

Meng Wang, Zili Shao

Reducing memory accesses is particularly important for DSP applications since they are widely used in embedded systems and need to be executed with high performance and low power consumption. In this...

Single Neuron Local Rational Arithmetic Revealed in Phase Space of Input Conductances (2008)

Meng Wang, Chang N. Zhang

ABSTRACT We present a phase space analysis to explore the potential of single neuron local arithmetic operations on its input conductances. This analysis was conducted first by deriving a rational...

Predictor Surfaces for Lip Synchronization Animation of Voiced Input (2008)

Rika Krothapalli, David F. Mcallister, Robert D. Rodman, Donald Bitzer, Meng Wang, Jamie Taylor

The authors are producing two-dimensional animated human faces with lip motion synchronized to a given speech sound file. The process is called lip synchronization. We assume the only input is the...

Speaker Independence in Lip Synchronization of Vowels (2008)

Jamie Taylor, Donald Bitzer, Robert Rodman, David Mcallister, Meng Wang

This paper presents a method for achieving speaker independence in the lip synchronization of vowels by performing an affine transformation on the moments of the spectrum of the speech. A speech...

GADTless Programming in Haskell 98 (2008)

Martin Sulzmann, Meng Wang

Abstract. Generalized algebraic data types (GADTs) allow to write sophisticated, type-safe programs and transformations. But not many languages, respectively their underlying implementations, support...

Translating Generalized Algebraic Data Types (2008)

To System F, Martin Sulzmann, Meng Wang

1 Introduction Generalized algebraic data types (GADTs) are an extension of (boxed) existen-tial types [17]. The novelty of GADTs is that we may include syntactic type equality constraints, i.e....

HIGH-LEVEL FEATURE EXTRACTION AND RUSHES EXPLOITATION (2008)

Xian-sheng Hua, Tao Mei, Wei Lai, Meng Wang, Jinhui Tang, Guo-jun Qi, ...

In this paper, we describe the MSRA experiments for TRECVID 2006, including details of the approaches and performance analyses for high-level feature extraction task and rushes exploitation task. For...

Implementing Hybrid Operating Systems with Two-Level Hardware Interrupts £ (2008)

Miao Liu, Zili Shao, Meng Wang, Hongxing Wei, Tianmiao Wang

In this paper, we propose to implement hybrid operating systems based on two-level hardware interrupts. To separate real-time and non-real-time hardware interrupts by hardware, we show that it is...

The Integration of State Space into the Dynamic Synthesis/Design and Operational/Control Optimization of a PEMFC System (2008)

Wang, Meng

ABSTRACT A typical approach to the synthesis/design optimization of energy systems is to only use steady state operation and high efficiency (or low total life cycle cost) at full load as the basis...

The Integration of State Space into the Dynamic Synthesis/Design and Operational/Control Optimization of a PEMFC System (2008)

Wang, Meng

ABSTRACT A typical approach to the synthesis/design optimization of energy systems is to only use steady state operation and high efficiency (or low total life cycle cost) at full load as the basis...

Generic and Indexed Programming (Project Paper) (2008)

Jeremy Gibbons, Meng Wang

The EPSRC-funded Generic and Indexed Programming project will explore the interaction between datatype-generic programming (DGP) — programs parametrized by the shape of their data — and indexed...

MSRA-USTC-SJTU AT TRECVID 2007: HIGH-LEVEL FEATURE EXTRACTION AND SEARCH (2008)

Tao Mei, Xian-sheng Hua, Wei Lai, Linjun Yang, Zheng-jun Zha, Yuan Liu, ...

This paper describes the MSRA-USTC-SJTU experiments for TRECVID 2007. We performed the experiments in high-level feature extraction and automatic search tasks. For high-level feature extraction, we...

Abstract A Compilation Model for Aspect-Oriented Polymorphically Typed Functional Languages (Technical Report) (2008)

Meng Wang, Shu-chun Weng

Introducing aspect orientation to a polymorphically typed functional language strengthens the importance of type-scoped advices; i.e., advices with their effects being harnessed by type constraints....

An Efficient Automatic Video Shot Size Annotation Scheme* (2008)

Meng Wang, Xian-sheng Hua, Yan Song, Wei Lai, Li-rong Dai, Ren-hua Wang

Abstract. This paper presents an efficient learning scheme for automatic annotation of video shot size. Instead of existing methods that applied in sports videos using domain knowledge, we are aiming...

ABSTRACT Optimizing Multi-Graph Learning: Towards A Unified Video Annotation Scheme (2008)

Meng Wang, Xian-sheng Hua, Xun Yuan, Yan Song, Li-rong Dai

Learning based semantic video annotation is a promising approach for enabling content-based video search. However, severe difficulties, such as insufficiency of training data and curse of...

ABSTRACT Structure-Sensitive Manifold Ranking for Video Concept Detection (2008)

Jinhui Tang, Xian-sheng Hua, Meng Wang, Tao Mei, Guo-jun Qi, Xiuqing Wu

Pairwise similarity of samples is an essential factor in graph propagation based semi-supervised learning methods. Usually it is estimated based on Euclidean distance. However, the structural...

2-(1H-Benzotriazol-1-yl)-1-(4-bromobenzoyl)ethyl 4-methylbenzoate (2008)

Jiu-Long Sun, Meng Wang, Ying-Jie Zhu, Fang Li, Sai Bi

In the molecule of the title compound, C23H18BrN3O3, the benzotriazole mean plane makes dihedral angles of 1.26 (1) and 87.39 (1)° with the tolyl and bromophenyl benzene rings,...

6,6′-Oxydichroman (2008)

Meng Wang, Yong-Hao Ye

The title compound, C18H18O3, was synthesized from dichroman in concentrated sulfuric acid. The molecule has a twofold axis passing through the central O atom. The dihedral angle between the two...

Novel cell segmentation and online SVM for cell cycle phase identification in automated microscopy (2008)

Wang, Meng, Zhou, Xiaobo, Li, Fuhai, Huckins, Jeremy, King, Randall W., Wong, Stephen T.C.

Motivation: Automated identification of cell cycle phases captured via fluorescent microscopy is very important for understanding cell cycle and for drug discovery. In this article, we propose a...

A model for familial exudative vitreoretinopathy caused by LPR5 mutations (2008)

Xia, Chun-Hong, Liu, Haiquan, Cheung, Debra, Wang, Meng, Cheng, Catherine, Du, Xin, ...

We have identified a mouse recessive mutation that leads to attenuated and hyperpermeable retinal vessels, recapitulating some pathological features of familial exudative vitreoretinopathy (FEVR) in...

Single Neuron Local Rational Arithmetic Revealed in Phase Space of Input Conductances (2007)

Meng Wang, Chang N. Zhang

A phase space analysis is presented to explore the potential of single neuron local arithmetic operations on its input conductances. This analysis is conducted first by deriving a rational function...

Corrigendum: High-throughput oncogene mutation profiling in human cancer. (2007)

Thomas, Roman K, Baker, Alissa C, Debiasi, Ralph M, Winckler, Wendy, Laframboise, Thomas, Lin, William M, ...

Systematic efforts are underway to decipher the genetic changes associated with tumor initiation and progression1, 2. However, widespread clinical application of this information is hampered by an...

Context based mixture model for cell phase identification in automated fluorescence microscopy (2007)

Wang, Meng, Zhou, Xiaobo, King, Randy W, Wong, Stephen TC

Abstract Background Automated identification of cell cycle phases of individual live cells in a large population captured via automated fluorescence microscopy technique is important for cancer drug...

Impact of dissoved oxygen performance on the operational cost of activated sludge process (2007)

Wang, Meng

This thesis is submitted in partial fulfilment of the requirements for the degree of Master of Science. The thesis sets out the results of a structured programme of research or design, development or...

BioMed Central (2007)

Bmc Bioinformatics, Meng Wang, Xiaobo Zhou, Y W King, Stephen Tc Wong, Randy W King, ...

Research article Context based mixture model for cell phase identification in automated fluorescence microscopy

Wall Models for Large-Eddy Simulation Based on Optimal Control Theory (2006)

Moin, Parviz, Templeton, Jeremy A., Wang, Meng

Large-eddy simulation (LES) requires very high resolution in high Reynolds number, attached turbulent boundary layers due to the need to capture the small, dynamically important near-wall eddies....

Interpretation of interference signals in label free integrated interferometric biosensors (2006)

Heikkinen, Hanna, Wang, Meng, Okkonen, Matti, Hast, Jukka, Myllylä, Risto

Proceedings of The International Society for Optical Engineering (SPIE); Optical Diagnostics and Sensing V. San Jose USA 21.-26.1.2006, 138 - 148

Aspect-oriented programming with type classes. http://www.comp.nus.edu.sg/˜ sulzmann (2006)

Martin Sulzmann, Meng Wang

What’s this talk about? Aspect-oriented programming (AOP) is an emerging paradigm to aid the user in the modularization of cross-cutting concerns. Type classes are an established concept to support...

Exposure to a Nutrition Supplementation Intervention in Early Childhood and Risk Factors for Cardiovascular Disease in Adulthood: Evidence from Guatemala (2006)

Stein, Aryeh D., Wang, Meng, Ramirez-Zea, Manuel, Flores, Rafael, Grajeda, Ruben, Melgar, Paul, ...

To study the role of nutrition in the association of birth size and childhood growth with development of cardiovascular disease, the authors in 2002–2004 surveyed 665 men and 790 women aged 25–42...

Heavy Flavors in High Energy ep Collisions (2005)

Wang, Meng

Most recent measurements of open charm and beauty production in high energy ep collisions at HERA are reviewed. The measurements explored the different aspects of quantum chromodynamics involved in...

Instant order: an enterprise solution for chain restaurants management (2005)

Wang, Meng (王盟), Huang, Guanglin (黃光霖), Zhang, Wan (張琬)

Traditional restaurant is operated based on the paper form and verbal. It usually has the low collaborative efficiency and relatively high risk of errors. Based on the technology of .NET, Web Service...

Semi-automatic video annotation based on active learning with multiple complementary predictors (2005)

Yan Song, Xian-sheng Hua, Li-rong Dai, Meng Wang

In this paper, we will propose a novel semi-automatic annotation scheme for video semantic classification. It is well known that the large gap between high-level semantics and low-level features is...

On the Computation of Space-Time Correlations by Large-Eddy Simulation (2004)

He, Guo-Wei, Wang, Meng, Lele, Sanjiva K.

Sound radiated by turbulent flow is dependent on the space-time characteristics of the flow field. According to Lighthill's theory (Lighthill 1952; Proudman 1952), acoustic power spectra in the...

Constrained Aeroacoustic Shape Optimization Using the Surrogate Management Framework (2004)

Marsden, Alison L., Wang, Meng

Reduction of noise generated by turbulent flow past the trailing-edge of a lifting surface is a challenge in many aeronautical and naval applications. Numerical predictions of trailing-edge noise...

Weighted-support vector machines for predicting membrane protein types based on pseudo-amino acid composition. Protein (2004)

Meng Wang, Jie Yang, Guo-ping Liu, Zhi-jie Xu, Kuo-chen Chou, Prof Alan Fersht

Membrane proteins are generally classified into the following five types: (1) type I membrane protein, (2) type II membrane protein, (3) multipass transmembrane proteins, (4) lipid chain-anchored...

Weighted-support vector machines for predicting membrane protein types based on pseudo amino acid composition (2004)

Wang, Meng, Yang, Jie, Liu, Guo-Ping, Xu, Zhi-Jie, Chou, Kuo-Chen

Membrane proteins are generally classified into the following five types: (1) type I membrane protein, (2) type II membrane protein, (3) multipass transmembrane proteins, (4) lipid chain-anchored...

Weighted-support vector machines for predicting membrane protein types based on pseudo-amino acid composition (2004)

Wang, Meng, Yang, Jie, Liu, Guo-Ping, Xu, Zhi-Jie, Chou, Kuo-Chen

Membrane proteins are generally classified into the following five types: (1) type I membrane proteins, (2) type II membrane proteins, (3) multipass transmembrane proteins, (4) lipid chain-anchored...

Weighted-support vector machines for predicting membrane protein types based on pseudo amino acid composition (2004)

Wang, Meng, Yang, Jie, Liu, Guo-Ping, Xu, Zhi-Jie, Chou, Kuo-Chen

Membrane proteins are generally classified into the following five types: (1) type I membrane protein, (2) type II membrane protein, (3) multipass transmembrane proteins, (4) lipid chain-anchored...

Development of Digital Signal Processing and Statistical Classification Methods for Distinguishing Nasal Consonants (2003)

Wang, Meng

Abstract WANG, MENG. Development of Digital Signal Processing and Statistical Classification Methods for Distinguishing Nasal Consonants. (Under the direction of David McAllister.) For almost half a...

Solid Rocket Combustion Phenomena. (1998)

Kassoy, David R., Wang, Meng, Zhao, Qing

This Final Technical Report describes completed research accomplishments and ongoing activities that are focused on the evolution of boundary driven acoustic disturbances in a low Mach number shear...

Wall Modeling Techniques for Large-Eddy Simulation (1998)

Moin, Parviz, Templeton, Jeremy, Wang, Meng, Nicoud, Franck, Baggett, Jeffrey

In the LEE of high Reynolds number wall-bounded flows, wall modeling is needed to alleviate the severe near-wall resolution requirement. Simple algebraic models such as the instantaneous log-law are...

Optimal Aeroacoustic Shape Design Using the Surrogate Management Framework (1998)

Marsden, Alison L., Wang, Meng, Dennis Jr, John E., Moin, Parviz

Shape optimization is applied to time-dependent trailing-edge flow in order to minimize aerodynamic noise. Optimization is performed using the surrogate management framework (SMF), a non-gradient...

The CCR5 receptor acts as an alloantigen in CCR5Δ32 homozygous individuals: Identification of chemokineand HIV-1-blocking human antibodies

Ditzel, Henrik J., Rosenkilde, Mette M., Garred, Peter, Wang, Meng, Koefoed, Klaus, Pedersen, Court, ...

The chemokine receptor CCR5 is the major coreceptor for infection by macrophage-tropic R5 HIV-1. A 32-bp deletion in the gene coding for CCR5 (CCR5Δ32) occurs with a frequency of 10% in the...

Antibody Neutralization-Resistant Primary Isolates of Human Immunodeficiency Virus Type 1

Wang, Meng, Trkola, Alexandra, Binley, James M., Purtscher, Martin, Katinger, Hermann, ...

Although typical primary isolates of human immunodeficiency virus type 1 (HIV-1) are relatively neutralization resistant, three human monoclonal antibodies and a small number of HIV-1+ human sera...

Broadly Neutralizing Antibodies Targeted to the Membrane-Proximal External Region of Human Immunodeficiency Virus Type 1 Glycoprotein gp41

Zwick, Michael B., Labrijn, Aran F., Wang, Meng, Spenlehauer, Catherine, Saphire, Erica Ollmann, Binley, James M., ...

The identification and epitope mapping of broadly neutralizing anti-human immunodeficiency virus type 1 (HIV-1) antibodies (Abs) is important for vaccine design, but, despite much effort, very few...

Neutralization Synergy of Human Immunodeficiency Virus Type 1 Primary Isolates by Cocktails of Broadly Neutralizing Antibodies

Zwick, Michael B., Wang, Meng, Poignard, Pascal, Stiegler, Gabriela, Katinger, Hermann, Burton, Dennis R., ...

Several reports have described the existence of synergy between neutralizing monoclonal antibodies (MAbs) against human immunodeficiency virus type 1 (HIV-1). Synergy between human MAbs b12, 2G12,...

Heterogeneity of Envelope Molecules Expressed on Primary Human Immunodeficiency Virus Type 1 Particles as Probed by the Binding of Neutralizing and Nonneutralizing Antibodies

Poignard, Pascal, Moulard, Maxime, Golez, Edwin, Vivona, Veronique, Franti, Michael, Venturini, Sara, ...

Virion capture assays, in which immobilized antibodies (Abs) capture virus particles, have been used to suggest that nonneutralizing Abs bind effectively to human immunodeficiency virus type 1...

Molecular Features of the Broadly Neutralizing Immunoglobulin G1 b12 Required for Recognition of Human Immunodeficiency Virus Type 1 gp120

Zwick, Michael B., Saphire, Erica O., Church, Sarah, Wang, Meng, Scott, Jamie K., ...

IgG1 b12 is a broadly neutralizing antibody against human immunodeficiency virus type 1 (HIV-1). The epitope recognized by b12 overlaps the CD4 receptor-binding site (CD4bs) on gp120 and has been a...

A Novel Human Antibody against Human Immunodeficiency Virus Type 1 gp120 Is V1, V2, and V3 Loop Dependent and Helps Delimit the Epitope of the Broadly Neutralizing Antibody Immunoglobulin G1 b12

Zwick, Michael B., Kelleher, Robert, Jensen, Richard, Labrijn, Aran F., Wang, Meng, ...

The V1/V2 and V3 loops are proximal to the CD4 binding site (CD4bs) of human immunodeficiency virus type 1 (HIV-1) gp120 and undergo conformational change upon CD4 receptor engagement by the HIV-1...

The Long Third Complementarity-Determining Region of the Heavy Chain Is Important in the Activity of the Broadly Neutralizing Anti-Human Immunodeficiency Virus Type 1 Antibody 2F5

Zwick, Michael B., Komori, H. Kiyomi, Stanfield, Robyn L., Church, Sarah, Wang, Meng, ...

The human monoclonal antibody 2F5 neutralizes primary human immunodeficiency virus type 1 (HIV-1) with rare breadth and potency. A crystal structure of a complex of 2F5 and a peptide corresponding to...

Comprehensive Cross-Clade Neutralization Analysis of a Panel of Anti-Human Immunodeficiency Virus Type 1 Monoclonal Antibodies

Binley, James M., Wrin, Terri, Korber, Bette, Zwick, Michael B., Wang, Meng, Chappey, Colombe, ...

Broadly neutralizing monoclonal antibodies (MAbs) are potentially important tools in human immunodeficiency virus type 1 (HIV-1) vaccine design. A few rare MAbs have been intensively studied, but we...

Anti-Human Immunodeficiency Virus Type 1 (HIV-1) Antibodies 2F5 and 4E10 Require Surprisingly Few Crucial Residues in the Membrane-Proximal External Region of Glycoprotein gp41 To Neutralize HIV-1

Zwick, Michael B., Jensen, Richard, Church, Sarah, Wang, Meng, Stiegler, Gabriela, Kunert, Renate, ...

The conserved membrane-proximal external region (MPER) of human immunodeficiency virus type 1 (HIV-1) gp41 is a target of two broadly neutralizing human monoclonal antibodies, 2F5 and 4E10, and is an...

The CCR5 receptor acts as an alloantigen in CCR5Δ32 homozygous individuals: Identification of chemokineand HIV-1-blocking human antibodies

Ditzel, Henrik J., Rosenkilde, Mette M., Garred, Peter, Wang, Meng, Koefoed, Klaus, Pedersen, Court, ...

The chemokine receptor CCR5 is the major coreceptor for infection by macrophage-tropic R5 HIV-1. A 32-bp deletion in the gene coding for CCR5 (CCR5Δ32) occurs with a frequency of 10% in the...

Antibody Neutralization-Resistant Primary Isolates of Human Immunodeficiency Virus Type 1

Wang, Meng, Trkola, Alexandra, Binley, James M., Purtscher, Martin, Katinger, Hermann, ...

Although typical primary isolates of human immunodeficiency virus type 1 (HIV-1) are relatively neutralization resistant, three human monoclonal antibodies and a small number of HIV-1+ human sera...

Broadly Neutralizing Antibodies Targeted to the Membrane-Proximal External Region of Human Immunodeficiency Virus Type 1 Glycoprotein gp41

Zwick, Michael B., Labrijn, Aran F., Wang, Meng, Spenlehauer, Catherine, Saphire, Erica Ollmann, Binley, James M., ...

The identification and epitope mapping of broadly neutralizing anti-human immunodeficiency virus type 1 (HIV-1) antibodies (Abs) is important for vaccine design, but, despite much effort, very few...

Neutralization Synergy of Human Immunodeficiency Virus Type 1 Primary Isolates by Cocktails of Broadly Neutralizing Antibodies

Zwick, Michael B., Wang, Meng, Poignard, Pascal, Stiegler, Gabriela, Katinger, Hermann, Burton, Dennis R., ...

Several reports have described the existence of synergy between neutralizing monoclonal antibodies (MAbs) against human immunodeficiency virus type 1 (HIV-1). Synergy between human MAbs b12, 2G12,...

Heterogeneity of Envelope Molecules Expressed on Primary Human Immunodeficiency Virus Type 1 Particles as Probed by the Binding of Neutralizing and Nonneutralizing Antibodies

Poignard, Pascal, Moulard, Maxime, Golez, Edwin, Vivona, Veronique, Franti, Michael, Venturini, Sara, ...

Virion capture assays, in which immobilized antibodies (Abs) capture virus particles, have been used to suggest that nonneutralizing Abs bind effectively to human immunodeficiency virus type 1...

Molecular Features of the Broadly Neutralizing Immunoglobulin G1 b12 Required for Recognition of Human Immunodeficiency Virus Type 1 gp120

Zwick, Michael B., Saphire, Erica O., Church, Sarah, Wang, Meng, Scott, Jamie K., ...

IgG1 b12 is a broadly neutralizing antibody against human immunodeficiency virus type 1 (HIV-1). The epitope recognized by b12 overlaps the CD4 receptor-binding site (CD4bs) on gp120 and has been a...

A Novel Human Antibody against Human Immunodeficiency Virus Type 1 gp120 Is V1, V2, and V3 Loop Dependent and Helps Delimit the Epitope of the Broadly Neutralizing Antibody Immunoglobulin G1 b12

Zwick, Michael B., Kelleher, Robert, Jensen, Richard, Labrijn, Aran F., Wang, Meng, ...

The V1/V2 and V3 loops are proximal to the CD4 binding site (CD4bs) of human immunodeficiency virus type 1 (HIV-1) gp120 and undergo conformational change upon CD4 receptor engagement by the HIV-1...

The Long Third Complementarity-Determining Region of the Heavy Chain Is Important in the Activity of the Broadly Neutralizing Anti-Human Immunodeficiency Virus Type 1 Antibody 2F5

Zwick, Michael B., Komori, H. Kiyomi, Stanfield, Robyn L., Church, Sarah, Wang, Meng, ...

The human monoclonal antibody 2F5 neutralizes primary human immunodeficiency virus type 1 (HIV-1) with rare breadth and potency. A crystal structure of a complex of 2F5 and a peptide corresponding to...

Comprehensive Cross-Clade Neutralization Analysis of a Panel of Anti-Human Immunodeficiency Virus Type 1 Monoclonal Antibodies

Binley, James M., Wrin, Terri, Korber, Bette, Zwick, Michael B., Wang, Meng, Chappey, Colombe, ...

Broadly neutralizing monoclonal antibodies (MAbs) are potentially important tools in human immunodeficiency virus type 1 (HIV-1) vaccine design. A few rare MAbs have been intensively studied, but we...

Anti-Human Immunodeficiency Virus Type 1 (HIV-1) Antibodies 2F5 and 4E10 Require Surprisingly Few Crucial Residues in the Membrane-Proximal External Region of Glycoprotein gp41 To Neutralize HIV-1

Zwick, Michael B., Jensen, Richard, Church, Sarah, Wang, Meng, Stiegler, Gabriela, Kunert, Renate, ...

The conserved membrane-proximal external region (MPER) of human immunodeficiency virus type 1 (HIV-1) gp41 is a target of two broadly neutralizing human monoclonal antibodies, 2F5 and 4E10, and is an...

An Affinity-Enhanced Neutralizing Antibody against the Membrane-Proximal External Region of Human Immunodeficiency Virus Type 1 gp41 Recognizes an Epitope between Those of 2F5 and 4E10▿

Nelson, Josh D., Brunel, Florence M., Jensen, Richard, Crooks, Emma T., Cardoso, Rosa M. F., Wang, Meng, ...

The membrane-proximal external region (MPER) of human immunodeficiency virus type 1 (HIV-1) gp41 bears the epitopes of two broadly neutralizing antibodies (Abs), 2F5 and 4E10, making it a target for...

The Human Immunodeficiency Virus Type 1 Envelope Spike of Primary Viruses Can Suppress Antibody Access to Variable Regions▿

Pantophlet, Ralph, Wang, Meng, Aguilar-Sino, Rowena O., Burton, Dennis R.

The human immunodeficiency virus type 1 (HIV-1) envelope spike is a heavily glycosylated trimeric structure in which protein surfaces conserved between different HIV-1 isolates are particularly well...

Different responses of two Mosla species to potassium limitation in relation to acid rain deposition*

Wang, Meng, Gu, Bao-jing, Ge, Ying, Liu, Zhen, Jiang, De-an, Chang, Scott X., ...

The increasingly serious problem of acid rain is leading to increased potassium (K) loss from soils, and in our field investigation, we found that even congenerically relative Mosla species show...

Protective effect of prednisolone on ischemia-induced liver injury in rats

Wang, Meng, Shen, Feng, Shi, Le-Hua, Xi, Tao, Li, Xi-Feng, Chen, Xu, ...

AIM: To investigate the effects of prednisolone on cell membrane bleb formation, calpain μ activation and talin degradation during hepatic ischemia-reperfusion injury in rats.

Function of Neuromuscular Synapses in the Zebrafish Choline-Acetyltransferase Mutant bajan

Wang, Meng, Wen, Hua, Brehm, Paul

We have identified a zebrafish mutant line, bajan, in which compromised motility and fatigue result from a point mutation in the gene coding choline acetyltransferase (ChAT), the enzyme responsible...