Michèle Bouloy

Characterisation of immune responses and protective efficacy in mice after immunisation with Rift Valley Fever virus cDNA constructs (2009)

Lagerqvist, Nina, Näslund, Jonas, Lundkvist, Åke, Bouloy, Michèle, Ahlm, Clas, Bucht, Göran

Abstract Background Affecting both livestock and humans, Rift Valley Fever is considered as one of the most important viral zoonoses in Africa. However, no licensed vaccines or effective treatments...

A SAP30 Complex Inhibits IFN-β Expression in Rift Valley Fever Virus Infected Cells (2008)

Nicolas Le May, Zeyni Mansuroglu, Psylvia Léger, Thibaut Josse, Guillaume Blot, Agnès Billecocq, ...

Rift Valley fever virus (RVFV) nonstructural protein NSs acts as the major determinant of virulence by antagonizing interferon β (IFN-β) gene expression. We demonstrate here that NSs interacts with...

Inversing the natural hydrogen bonding rule to selectively amplify GC-rich ADAR-edited RNAs. (2008)

Suspène, Rodolphe, Renard, Myrtille, Henry, Michel, Guétard, Denise, Puyraimond-Zemmour, David, Billecocq, Agnès, ...

DNA complementarity is expressed by way of three hydrogen bonds for a G:C base pair and two for A:T. As a result, careful control of the denaturation temperature of PCR allows selective amplification...

Inversing the natural hydrogen bonding rule to selectively amplify GC-rich ADAR-edited RNAs. (2008)

Suspène, Rodolphe, Renard, Myrtille, Henry, Michel, Guétard, Denise, Puyraimond-Zemmour, David, Billecocq, Agnès, ...

DNA complementarity is expressed by way of three hydrogen bonds for a G:C base pair and two for A:T. As a result, careful control of the denaturation temperature of PCR allows selective amplification...

Inversing the natural hydrogen bonding rule to selectively amplify GC-rich ADAR-edited RNAs (2008)

Suspène, Rodolphe, Renard, Myrtille, Henry, Michel, Guétard, Denise, Puyraimond-Zemmour, David, Billecocq, Agnès, ...

DNA complementarity is expressed by way of three hydrogen bonds for a G:C base pair and two for A:T. As a result, careful control of the denaturation temperature of PCR allows selective amplification...

A SAP30 complex inhibits IFN-beta expression in Rift Valley fever virus infected cells. (2008)

Le May, Nicolas, Mansuroglu, Zeyni, Léger, Psylvia, Josse, Thibaut, Blot, Guillaume, Billecocq, Agnès, ...

Rift Valley fever virus (RVFV) nonstructural protein NSs acts as the major determinant of virulence by antagonizing interferon beta (IFN-beta) gene expression. We demonstrate here that NSs interacts...

A SAP30 complex inhibits IFN-beta expression in Rift Valley fever virus infected cells. (2008)

Le May, Nicolas, Mansuroglu, Zeyni, Léger, Psylvia, Josse, Thibaut, Blot, Guillaume, Billecocq, Agnès, ...

Rift Valley fever virus (RVFV) nonstructural protein NSs acts as the major determinant of virulence by antagonizing interferon beta (IFN-beta) gene expression. We demonstrate here that NSs interacts...

Modulations of the in vitro translational efficiencies of Yellow Fever virus mRNAs: interactions between coding and noncoding regions (1989)

Ruiz-Linares, Andrès, Bouloy, Michèle, Girard, Marc, Cahour, Annie

As an approach to define the structural features within the 5′ noncoding region of Yellow Fever virus (YFV) that modulate mRNA translational efficiency, we have studied how minor changes In this...

The Carboxy-Terminal Acidic Domain of Rift Valley Fever Virus NSs Protein Is Essential for the Formation of Filamentous Structures but Not for the Nuclear Localization of the Protein

Yadani, Fatima-Zahra, Kohl, Alain, Préhaud, Christophe, Billecocq, Agnès, Bouloy, Michèle

The ambisense S segment of Rift Valley fever (RVF) virus (a phlebovirus in the Bunyaviridae family) codes for two proteins: the viral complementary-sense RNA for the N nucleoprotein and the...

Genetic Evidence for an Interferon-Antagonistic Function of Rift Valley Fever Virus Nonstructural Protein NSs

Bouloy, Michèle, Janzen, Christian, Vialat, Pierre, Khun, Huot, Pavlovic, Jovan, Huerre, Michel, ...

Rift Valley fever virus (RVFV), a phlebovirus of the family Bunyaviridae, is a major public health threat in Egypt and sub-Saharan Africa. The viral and host cellular factors that contribute to RVFV...

NSs Protein of Rift Valley Fever Virus Blocks Interferon Production by Inhibiting Host Gene Transcription

Billecocq, Agnès, Spiegel, Martin, Vialat, Pierre, Kohl, Alain, Weber, Friedemann, Bouloy, Michèle, ...

Rift Valley fever virus (RVFV) is an important cause of epizootics and epidemics in Africa and a potential agent of bioterrorism. A better understanding of the factors that govern RVFV virulence and...

The N Terminus of Rift Valley Fever Virus Nucleoprotein Is Essential for Dimerization

Le May, Nicolas, Gauliard, Nicolas, Billecocq, Agnès, Bouloy, Michèle

Rift Valley fever virus (RVFV) is a Phlebovirus in the Bunyaviridae family. The nucleoprotein N is the most abundant component of the virion; numerous copies of N associate with the viral RNA genome...

Nairovirus RNA Sequences Expressed by a Semliki Forest Virus Replicon Induce RNA Interference in Tick Cells

Garcia, Stephan, Billecocq, Agnès, Crance, Jean-Marc, Munderloh, Ulrike, Garin, Daniel, Bouloy, Michèle

We report the successful infection of the cell line ISE6 derived from Ixodes scapularis tick embryos by the tick-borne Hazara virus (HAZV), a nairovirus in the family Bunyaviridae. Using a...

The Carboxy-Terminal Acidic Domain of Rift Valley Fever Virus NSs Protein Is Essential for the Formation of Filamentous Structures but Not for the Nuclear Localization of the Protein

Yadani, Fatima-Zahra, Kohl, Alain, Préhaud, Christophe, Billecocq, Agnès, Bouloy, Michèle

The ambisense S segment of Rift Valley fever (RVF) virus (a phlebovirus in the Bunyaviridae family) codes for two proteins: the viral complementary-sense RNA for the N nucleoprotein and the...

Genetic Evidence for an Interferon-Antagonistic Function of Rift Valley Fever Virus Nonstructural Protein NSs

Bouloy, Michèle, Janzen, Christian, Vialat, Pierre, Khun, Huot, Pavlovic, Jovan, Huerre, Michel, ...

Rift Valley fever virus (RVFV), a phlebovirus of the family Bunyaviridae, is a major public health threat in Egypt and sub-Saharan Africa. The viral and host cellular factors that contribute to RVFV...

NSs Protein of Rift Valley Fever Virus Blocks Interferon Production by Inhibiting Host Gene Transcription

Billecocq, Agnès, Spiegel, Martin, Vialat, Pierre, Kohl, Alain, Weber, Friedemann, Bouloy, Michèle, ...

Rift Valley fever virus (RVFV) is an important cause of epizootics and epidemics in Africa and a potential agent of bioterrorism. A better understanding of the factors that govern RVFV virulence and...

Nairovirus RNA Sequences Expressed by a Semliki Forest Virus Replicon Induce RNA Interference in Tick Cells

Garcia, Stephan, Billecocq, Agnès, Crance, Jean-Marc, Munderloh, Ulrike, Garin, Daniel, Bouloy, Michèle

We report the successful infection of the cell line ISE6 derived from Ixodes scapularis tick embryos by the tick-borne Hazara virus (HAZV), a nairovirus in the family Bunyaviridae. Using a...

The N Terminus of Rift Valley Fever Virus Nucleoprotein Is Essential for Dimerization

Le May, Nicolas, Gauliard, Nicolas, Billecocq, Agnès, Bouloy, Michèle

Rift Valley fever virus (RVFV) is a Phlebovirus in the Bunyaviridae family. The nucleoprotein N is the most abundant component of the virion; numerous copies of N associate with the viral RNA genome...

A SAP30 Complex Inhibits IFN-β Expression in Rift Valley Fever Virus Infected Cells

Le May, Nicolas, Mansuroglu, Zeyni, Léger, Psylvia, Josse, Thibaut, Blot, Guillaume, Billecocq, Agnès, ...

Rift Valley fever virus (RVFV) nonstructural protein NSs acts as the major determinant of virulence by antagonizing interferon β (IFN-β) gene expression. We demonstrate here that NSs interacts with...

Inversing the natural hydrogen bonding rule to selectively amplify GC-rich ADAR-edited RNAs

Suspène, Rodolphe, Renard, Myrtille, Henry, Michel, Guétard, Denise, Puyraimond-Zemmour, David, Billecocq, Agnès, ...

DNA complementarity is expressed by way of three hydrogen bonds for a G:C base pair and two for A:T. As a result, careful control of the denaturation temperature of PCR allows selective amplification...

Real-Time Reverse-Transcription Loop-Mediated Isothermal Amplification for Rapid Detection of Rift Valley Fever Virus▿

Peyrefitte, Christophe N., Boubis, Laetitia, Coudrier, Daniel, Bouloy, Michèle, Grandadam, Marc, Tolou, Hugues J., ...

The development and validation of a one-step, single-tube, real-time accelerated reverse-transcription loop-mediated isothermal amplification (RT-LAMP) for the detection of the L RNA segment of Rift...