Jacob D. Jaffe, D. R. Mani, Kyriacos C. Leptos, George M. Church, Michael A. Gillette, Steven A. Carr
Quantitative proteomics holds considerable promise for elucidation of basic biology and for clinical biomarker discovery. However, it has been difficult to fulfill this promise due to over-reliance...
PEPPeR, a Platform for Experimental Proteomic Pattern Recognition (2006)
Jacob D. Jaffe, D. R. Mani, Kyriacos C. Leptos, George M. Church, Michael A. Gillette, Steven A. Carr
Quantitative proteomics holds considerable promise for elucidation of basic biology and for clinical biomarker discovery. However, it has been difficult to fulfill this promise due to over-reliance...
Subramanian, Aravind, Tamayo, Pablo, Mootha, Vamsi K., Mukherjee, Sayan, Ebert, Benjamin L., Gillette, Michael A., ...
Although genomewide RNA expression analysis has become a routine tool in biomedical research, extracting biological insight from such information remains a major challenge. Here, we describe a...
Subramanian, Aravind, Tamayo, Pablo, Mootha, Vamsi K., Mukherjee, Sayan, Ebert, Benjamin L., Gillette, Michael A., ...
Although genomewide RNA expression analysis has become a routine tool in biomedical research, extracting biological insight from such information remains a major challenge. Here, we describe a...
Tamayo, Pablo, Scanfeld, Daniel, Ebert, Benjamin L., Gillette, Michael A., Roberts, Charles W. M., Mesirov, Jill P.
The high dimensionality of global transcription profiles, the expression level of 20,000 genes in a much small number of samples, presents challenges that affect the sensitivity and general...
PEPPeR: A Platform for Experimental Proteomic Pattern Recognition
Jaffe, Jacob D., Mani, D. R., Leptos, Kyriacos C., Church, George M., Gillette, Michael A., Carr, Steven A.
Jaffe, Jacob D., Keshishian, Hasmik, Chang, Betty, Addona, Theresa A., Gillette, Michael A., Carr, Steven A.
Verification of candidate biomarker proteins in blood is typically done using multiple reaction monitoring (MRM) of peptides by LC-MS/MS on triple quadrupole MS systems. MRM assay development for...