Bayesian optimal discovery procedure for simultaneous significance testing (2009)
Cao, Jing, Xie, Xian-Jin, Zhang, Song, Whitehurst, Angelique, White, Michael A
Abstract Background In high throughput screening, such as differential gene expression screening, drug sensitivity screening, and genome-wide RNAi screening, tens of thousands of tests need to be...
A global framework for monitoring phenological responses to (2008)
Michael A. White, Forrest Hoffman, William W. Hargrove, Ramakrishna R. Nemani
climate change
El Niño–Southern Oscillation–induced variability in terrestrial carbon cycling (2008)
Hirofumi Hashimoto, Ramakrishna R. Nemani, Michael A. White, William M. Jolly
[1] We examined the response of terrestrial carbon fluxes to climate variability induced by the El Niño–Southern Oscillation (ENSO). We estimated global net primary production (NPP) from 1982 to...
Shah, Jyoti K, Garner, Harold R, White, Michael A, Shames, David S, Minna, John D
Abstract Background RNA interference has revolutionized our ability to study the effects of altering the expression of single genes in mammalian (and other) cells through targeted knockdown of gene...
White, Michael A., Culbertson, Amy L.
The information presented here was gathered from a variety of sources, including interviews conducted with 39 ASO non-supervisory, supervisory, and managerial employees, along with a review of...
Delayed Entry Program Attrition: Survey Results (2006)
Lane, Marian E., Johns, Charles W., White, Michael A., Eshwar, Naina C.
The Navy's Delayed Entry Program (DEP) allows individuals to delay their entry into the Navy for up to one year after signing an enlistment contract. However, the DEP loses approximately 18 percent...
Merrill A. Peterson, Barbara M. Honchak, Stefanie E. Locke, Timothy E. Beeman, Jessica Mendoza, Jabin Green, ...
Most studies of reinforcement have focused on the evolution of either female choice or male mating cues, following the long-held view in sexual selection theory that mating mistakes are typically...
Biochemical and genetic analysis of the yeast proteome with a movable ORF collection (2005)
Gelperin, Daniel M., White, Michael A., Wilkinson, Martha L., Kon, Yoshiko, Kung, Li A., Wise, Kevin J., ...
Functional analysis of the proteome is an essential part of genomic research. To facilitate different proteomic approaches, a MORF (moveable ORF) library of 5854 yeast expression plasmids was...
A Practical Methodology for Identifying Impediments to Productivity. (2002)
White,Michael A., Atwater,Leanne Y., Mohr,Deborah A.
The methodology followed by NAVPERSRANDCEN in conducting an investigation of impediments to productivity at five Navy industrial facilities in 1980 is described in detail. The methodology included...
The Impact of Goal Setting and Feedback on the Productivity of Navy Industrial Workers. (2002)
Crawford,Kent S., White,Michael A., Magnusson,Paul A.
The objective of this effort was to implement and evaluate a goal-setting program for industrial workers at a Naval Air Rework Facility (NARF). This program attempted to improve worker motivation and...
Behavior and Effectiveness of First-Line Supervisors. (2002)
Atwater,Leanne E., White,Michael A.
The purpose of this study was to expand the current understanding of the factors related to first-line supervisory effectiveness. Data was collected from over 400 employees from three Navy Public...
A Field Study of an Individual Incentive System for Production Workers. (2002)
White,Michael A., Crawford,Kent S., Dockstader,Steven L.
An individual monetary incentive system was implemented in four shops at a Naval Air Rework Facility. Performance data were analyzed across baseline and incentive periods for four incentive shops and...
While not expressed in most adult human tissues, high levels of telomerase activity are present in most cancers. Expression of telomerase in many primary cell cultures is sufficient to bypass normal...
White, Michael A, Asner, Gregory P, Nemani, Ramakrishna R, Privette, Jeff L, Running, Steven W
Field measurement of shrubland ecological properties is important for both site monitoring and validation of remote sensing information. During the May 1997 NASA Earth Observing System Jornada...
Functional requirement of p23 and Hsp90 in telomerase complexes (1999)
Holt, Shawn E., Aisner, Dara L., Baur, Joseph, Tesmer, Valerie M., Dy, Marife, Ouellette, Michel, ...
Improving Performance of the Navy Intermediate Maintenance System in San Diego. (1998)
Feher, Bela, Riedel, James A., Farkas, Arthur J., White, Michael A., Millard, Warren J.
Navy repair activities are facing an increased workload at a time when the work force is being reduced. The demand for intermediate ship repairs is also increasing as periods between overhauls are...
An Evaluation of Quality Circles in Department of Defense Organizations. (1998)
White, Michael A., Konoske, Paula J.
This report describes the evaluation of quality circle programs in the Department of Defense (DoD). Rather than attempting to provide a final analysis of the value of quality circle programs to the...
Relationships Between Expectations and Life and Job Satisfaction, (1998)
Baker, Herbert G., White, Michael A.
The early stage of the military recruiting process is built on a loosely connected series of specific, but mostly general images, associations, and "like to have"s. It is clear that some well-formed...
Melvalonates, Ras and Breast Cancer (1998)
Therapy of any cancer is designed to control the growth of cancer cells while permitting the function and proliferation of normal cells. 6-fluoromevalonate (Fmev) can inhibit proliferation of...
Mevalonates, Ras and Breast Cancer (1998)
Therapy of any cancer is designed to control growth of cancer cells while permitting the function and proliferation of normal cells. 6-fluoromevalonate (Fmev) can inhibit proliferation of leukemic...
Isolation of Factors that Disrupt Critical Protein (1998)
One of the earliest events associated with the multistage pathogenesis of breast cancer is the activation of telomerase. Telomerase is a reverse transcriptase that elongates the ends of chromosomes...
Characterization of a Putative Tumor Suppressor in Breast Cancer (1998)
White, Michael A., Shivakumar, Latha, Thomas, Jackie
The RASSF1A locus at 3p21.3 is epigenetically inactivated at high frequency in a variety of solid tumors. We have shown that expression of RASSF1A is sufficient to revert the tumorigenicity of human...
Telomerase activity is required to maintain telomere integrity on chromosomes of proliferating cells and thus is critically involved in regulating cellular replicative lifespan. Telomerase is...
Characterization of a Putative Tumor Suppressor in Breast Cancer (1998)
Thomas, Jackie, White, Michael A.
Telomerase activity is required to maintain telomere integrity on chromosomes of proliferating cells and thus is critically involved in regulating cellular replicative lifespan. Telomerase is...
The decade of the 1970's : a science fiction renaissance / (1991)
Thesis (M.A.)--Bowling Green State University, 1991.
The influence of attributions on the subjective performance appraisal / (1990)
Typescript (photocopy).
Typescript.
History of education in Texas, 1860-1884--[microform]. (1969)
Thesis (Ed. D.)--Baylor University, 1969.
History of education in Texas, 1860-1884 /--by Michael Allen White. (1969)
Bibliography: leaves 333-339.
Ral GTPases Contribute to Regulation of Cyclin D1 through Activation of NF-κB
Henry, Dale O., Moskalenko, Serge A., Kaur, Kiran J., Fu, Maofu, Pestell, Richard G., Camonis, Jacques H., ...
Ral GTPases have been implicated as mediators of Ras-induced signal transduction from observations that Ral-specific guanine nucleotide exchange factors associate with Ras and are activated by Ras....
Differential Effects of Protein Kinase A on Ras Effector Pathways
Miller, Marsha J., Rioux, Lise, Prendergast, Gregory V., Cannon, Sarah, White, Michael A., Meinkoth, Judy L.
Ras mutants with the ability to interact with different effectors have played a critical role in the identification of Ras-dependent signaling pathways. We used two mutants, RasS35 and RasG37, which...
The RASSF1A Tumor Suppressor Blocks Cell Cycle Progression and Inhibits Cyclin D1 Accumulation
Shivakumar, Latha, Minna, John, Sakamaki, Toshiyuki, Pestell, Richard, White, Michael A.
The RASSF1A locus at 3p21.3 is epigenetically inactivated at high frequency in a variety of solid tumors. Expression of RASSF1A is sufficient to revert the tumorigenicity of human cancer cell lines....
Functional requirement of p23 and Hsp90 in telomerase complexes
Holt, Shawn E., Aisner, Dara L., Baur, Joseph, Tesmer, Valerie M., Dy, Marife, Ouellette, Michel, ...
Most normal human diploid cells have no detectable telomerase; however, expression of the catalytic subunit of telomerase is sufficient to induce telomerase activity and, in many cases, will bypass...
Whitehurst, Angelique, Cobb, Melanie H., White, Michael A.
Current understanding of cell regulatory systems suggests a diverse array of extracellular stimuli commonly recruit a limited cadre of core signal transduction modules to drive discrete...
RAL GTPases are linchpin modulators of human tumour-cell proliferation and survival
Chien, Yuchen, White, Michael A.
The monomeric RAL (RAS-like) GTPases have been indirectly implicated in mitogenic regulation and cell transformation. Here, we show that RALA and RALB collaborate to maintain tumorigenicity through...
RalB Mobilizes the Exocyst To Drive Cell Migration†
Rossé, Carine, Hatzoglou, Anastassia, Parrini, Maria-Carla, White, Michael A., Chavrier, Philippe, Camonis, Jacques
The Ras family GTPases RalA and RalB have been defined as central components of the regulatory machinery supporting tumor initiation and progression. Although it is known that Ral proteins mediate...
Biochemical and genetic analysis of the yeast proteome with a movable ORF collection
Gelperin, Daniel M., White, Michael A., Wilkinson, Martha L., Kon, Yoshiko, Kung, Li A., Wise, Kevin J., ...
Functional analysis of the proteome is an essential part of genomic research. To facilitate different proteomic approaches, a MORF (moveable ORF) library of 5854 yeast expression plasmids was...
Ral GTPases Contribute to Regulation of Cyclin D1 through Activation of NF-κB
Henry, Dale O., Moskalenko, Serge A., Kaur, Kiran J., Fu, Maofu, Pestell, Richard G., Camonis, Jacques H., ...
Ral GTPases have been implicated as mediators of Ras-induced signal transduction from observations that Ral-specific guanine nucleotide exchange factors associate with Ras and are activated by Ras....
Differential Effects of Protein Kinase A on Ras Effector Pathways
Miller, Marsha J., Rioux, Lise, Prendergast, Gregory V., Cannon, Sarah, White, Michael A., Meinkoth, Judy L.
Ras mutants with the ability to interact with different effectors have played a critical role in the identification of Ras-dependent signaling pathways. We used two mutants, RasS35 and RasG37, which...
The RASSF1A Tumor Suppressor Blocks Cell Cycle Progression and Inhibits Cyclin D1 Accumulation
Shivakumar, Latha, Minna, John, Sakamaki, Toshiyuki, Pestell, Richard, White, Michael A.
The RASSF1A locus at 3p21.3 is epigenetically inactivated at high frequency in a variety of solid tumors. Expression of RASSF1A is sufficient to revert the tumorigenicity of human cancer cell lines....
Functional requirement of p23 and Hsp90 in telomerase complexes
Holt, Shawn E., Aisner, Dara L., Baur, Joseph, Tesmer, Valerie M., Dy, Marife, Ouellette, Michel, ...
Most normal human diploid cells have no detectable telomerase; however, expression of the catalytic subunit of telomerase is sufficient to induce telomerase activity and, in many cases, will bypass...
Whitehurst, Angelique, Cobb, Melanie H., White, Michael A.
Current understanding of cell regulatory systems suggests a diverse array of extracellular stimuli commonly recruit a limited cadre of core signal transduction modules to drive discrete...
Biochemical and genetic analysis of the yeast proteome with a movable ORF collection
Gelperin, Daniel M., White, Michael A., Wilkinson, Martha L., Kon, Yoshiko, Kung, Li A., Wise, Kevin J., ...
Functional analysis of the proteome is an essential part of genomic research. To facilitate different proteomic approaches, a MORF (moveable ORF) library of 5854 yeast expression plasmids was...
RAL GTPases are linchpin modulators of human tumour-cell proliferation and survival
Chien, Yuchen, White, Michael A.
The monomeric RAL (RAS-like) GTPases have been indirectly implicated in mitogenic regulation and cell transformation. Here, we show that RALA and RALB collaborate to maintain tumorigenicity through...
RalB Mobilizes the Exocyst To Drive Cell Migration†
Rossé, Carine, Hatzoglou, Anastassia, Parrini, Maria-Carla, White, Michael A., Chavrier, Philippe, Camonis, Jacques
The Ras family GTPases RalA and RalB have been defined as central components of the regulatory machinery supporting tumor initiation and progression. Although it is known that Ral proteins mediate...
Whitehurst, Angelique W., Ram, Rosalyn, Shivakumar, Latha, Gao, Boning, Minna, John D., White, Michael A.
Multiple molecular lesions in human cancers directly collaborate to deregulate proliferation and suppress apoptosis to promote tumorigenesis. The candidate tumor suppressor RASSF1A is commonly...
Ganesan, Anand K., Ho, Hsiang, Bodemann, Brian, Petersen, Sean, Aruri, Jayavani, Koshy, Shiney, ...
Melanin protects the skin and eyes from the harmful effects of UV irradiation, protects neural cells from toxic insults, and is required for sound conduction in the inner ear. Aberrant regulation of...
Bayesian optimal discovery procedure for simultaneous significance testing
Cao, Jing, Xie, Xian-Jin, Zhang, Song, Whitehurst, Angelique, White, Michael A
Chen, Chiyuan, Lewis, Robert E., White, Michael A.
The Ras effector and ubiquitin-protein isopeptide ligase family member IMP acts as a steady-state resistor within the Raf-MEK-ERK kinase module. IMP concentrations are regulated by Ras through...
A Systematic Screen for Transcriptional Regulators of the Yeast Cell Cycle
White, Michael A., Riles, Linda, Cohen, Barak A.
Transcription factors play a key role in the regulation of cell cycle progression, yet many of the specific regulatory interactions that control cell cycle transcription are still unknown. To...
Fine-Scale Dissection of Functional Protein Network Organization by Statistical Network Analysis
Komurov, Kakajan, Gunes, Mehmet H., White, Michael A.
Revealing organizational principles of biological networks is an important goal of systems biology. In this study, we sought to analyze the dynamic organizational principles within the protein...
Fine-Scale Phylogenetic Discordance across the House Mouse Genome
White, Michael A., Ané, Cécile, Dewey, Colin N., Larget, Bret R., Payseur, Bret A.
Population genetic theory predicts discordance in the true phylogeny of different genomic regions when studying recently diverged species. Despite this expectation, genome-wide discordance in young...