Reversible protein acetylation is a mechanism used by the cell to regulate gene expression and other important activities such as stress response and apoptosis. Human SIRT1 is an NAD+ dependent...
Evan Keibler, Manimozhiyan Arumugam, Michael Brent, Alex Bateman
Motivation: Hidden Markov models (HMMs) and generalized HMMs been successfully applied to many problems, but the standard Viterbi Algorithm for computing the most probable interpretation of an input...
Cahan, Patrick, Godfrey, Laura E., Eis, Peggy S., Richmond, Todd A., Selzer, Rebecca R., Brent, Michael, ...
Copy number variants (CNVs) are currently defined as genomic sequences that are polymorphic in copy number and range in length from 1000 to several million base pairs. Among current array-based CNV...
Robin Dowell, Michael Brent, Sean Eddy, Gary Stormo
One goal of any genome project is the elucidation of the primary sequence of DNA contained within a given species. While the availability of the primary sequence itself is valuable, it does not reach...
Keibler, Evan, Arumugam, Manimozhiyan, Brent, Michael
Motivation: Hidden Markov models (HMMs) and generalized HMMs been successfully applied to many problems, but the standard Viterbi Algorithm for computing the most probable interpretation of an input...
The Successes and Failures of Word-to-World Mapping (1999)
Jesse Snedeker, Lila Gleitman, Michael Brent
Introduction This research examines how children begin learning the meanings of words. Necessarily, novice word-learners must start by pairing a word form with the scenes in which it occurs,...
Towards a Unified Model of Lexical Acquisition and Lexical Access (1996)
Much effort has gone into constructing models of how children segment speech and thereby discover the words of their language. Much effort has also gone into constructing models of how adults access...
How could children possibly acquire their first subcategorization frames? The hypothesis that they directly observe the syntactic structures of the utterances they hear raises two questions. First,...
Causal/Temporal Connectives: Syntax and Lexicon (1989)
Abstract: This report elucidates the linguistic representation of temporal relations among events. It does so by examining sentences that contain two clauses connected words like once, by the time,...
Cahan, Patrick, Godfrey, Laura E., Eis, Peggy S., Richmond, Todd A., Selzer, Rebecca R., Brent, Michael, ...
Copy number variants (CNVs) are currently defined as genomic sequences that are polymorphic in copy number and range in length from 1000 to several million base pairs. Among current array-based CNV...