A Stochastic Compartmental Model for Fast Axonal Transport (2009)
McKinley, Scott A., Popovic, Lea, Reed, Michael C.
In this paper we develop a probabilistic micro-scale model and use it to study macro-scale properties of axonal transport, the processes by which materials are moved in the axons of neurons. By...
Homeostatic mechanisms in dopamine synthesis and release: a mathematical model (2009)
Best, Janet A, Nijhout, H Frederik, Reed, Michael C
Abstract Background Dopamine is a catecholamine that is used as a neurotransmitter both in the periphery and in the central nervous system. Dysfunction in various dopaminergic systems is known to be...
A mathematical model of glutathione metabolism (2008)
Reed, Michael C, Thomas, Rachel L, Pavisic, Jovana, James, S Jill, Ulrich, Cornelia M, Nijhout, H Frederik
Abstract Background Glutathione (GSH) plays an important role in anti-oxidant defense and detoxification reactions. It is primarily synthesized in the liver by the transsulfuration pathway and...
In silico experimentation with a model of hepatic mitochondrial folate metabolism (2006)
Nijhout, H Frederik, Reed, Michael C, Lam, Shi-Ling, Shane, Barry, Gregory, Jesse F, Ulrich, Cornelia M
Abstract Background In eukaryotes, folate metabolism is compartmentalized and occurs in both the cytosol and the mitochondria. The function of this compartmentalization and the great changes that...
Washington, Talitha M, Blum, J Joseph, Reed, Michael C, Conn, P Michael
Abstract In a previous study, a model was developed to investigate the release of luteinizing hormone (LH) from pituitary cells in response to a short pulse of gonadotropin-releasing hormone (GnRH)....
Nonlinear superposition and absorption of delta waves in one space dimension (1987)
Rauch, Jeffrey, Reed, Michael C.
Peer Reviewed
Washington, Talitha M, Blum, J Joseph, Reed, Michael C, Conn, P Michael
In a previous study, a model was developed to investigate the release of luteinizing hormone (LH) from pituitary cells in response to a short pulse of gonadotropin-releasing hormone (GnRH). The model...
Boyles, Abee L., Billups, Ashley V., Deak, Kristen L., Siegel, Deborah G., Mehltretter, Lorraine, Slifer, Susan H., ...
In silico experimentation with a model of hepatic mitochondrial folate metabolism
Nijhout, H Frederik, Reed, Michael C, Lam, Shi-Ling, Shane, Barry, Gregory, Jesse F, Ulrich, Cornelia M
Washington, Talitha M, Blum, J Joseph, Reed, Michael C, Conn, P Michael
In a previous study, a model was developed to investigate the release of luteinizing hormone (LH) from pituitary cells in response to a short pulse of gonadotropin-releasing hormone (GnRH). The model...
Boyles, Abee L., Billups, Ashley V., Deak, Kristen L., Siegel, Deborah G., Mehltretter, Lorraine, Slifer, Susan H., ...
Leduc, Damien, Escartin, Frédéric, Nijhout, H. Frederik, Reed, Michael C., Liebl, Ursula, Skouloubris, Stéphane, ...
Although flavin-dependent ThyX proteins show thymidylate synthase activity in vitro and functionally complement thyA defects in heterologous systems, direct proof of their cellular functions is...