A halo model for intrinsic alignments of galaxy ellipticities (2009)
Schneider, Michael D., Bridle, Sarah
Correlations between intrinsic ellipticities of galaxies are a potentially important systematic error when constraining dark energy properties from weak gravitational lensing (cosmic shear) surveys....
Schneider, Michael D., Knox, Lloyd, Habib, Salman, Heitmann, Katrin, Higdon, David, Nakhleh, Charles
We describe an approximate statistical model for the sample variance distribution of the non-linear matter power spectrum that can be calibrated from limited numbers of simulations. Our model retains...
Ding, Guoliang, Fu, Mingui, Qin, Qianhong, Lewis, William, Kim, Ha Won, Fukai, Tohru, ...
Objectives Peroxisome proliferator-activated receptors (PPAR) α and β/δ are essential transcriptional regulators of fatty acid oxidation in the heart. However, little is known about the roles of...
Morley, Gregory E, Vance, Kendra M, Emile, Lorin, ...
Endocardial cushions are precursors of mature atrioventricular (AV) valves. Their formation is induced by signaling molecules originating from the AV myocardium, including bone morphogenetic proteins...
Mishina, Yuji, Hanks, Mark C, ...
Receptors for bone morphogenetic proteins (BMPs), members of the transforming growth factor-beta (TGFbeta) superfamily, are persistently expressed during cardiac development, yet mice lacking type II...
World view and role awareness in foreign policy decision making : the Berlin crisis of 1961 / (1978)
Schneider, Michael D. (Michael Donald)
Thesis (Ph. D.)--American University, 1978.
Oh, Hidemasa, Taffet, George E., Youker, Keith A., Entman, Mark L., Overbeek, Paul A., Michael, Lloyd H., ...
Cardiac muscle regeneration after injury is limited by “irreversible” cell cycle exit. Telomere shortening is one postulated basis for replicative senescence, via down-regulation of telomerase...
A Novel Rb- and p300-Binding Protein Inhibits Transactivation by MyoD
MacLellan, W. Robb, Xiao, G., Abdellatif, M., Schneider, Michael D.
The retinoblastoma protein (Rb) regulates both the cell cycle and tissue-specific transcription, by modulating the activity of factors that associate with its A-B and C pockets. In skeletal muscle,...
Abdellatif, Maha, Packer, Sharon E., Michael, Lloyd H., Zhang, Dou, Charng, Min Ji, Schneider, Michael D.
Despite extensive evidence implicating Ras in cardiac muscle hypertrophy, the mechanisms involved are unclear. We previously reported that Ras, through an effector-like function of Ras...
Gaussin, Vinciane, Van De Putte, Tom, Mishina, Yuji, Hanks, Mark C., Zwijsen, An, Huylebroeck, Danny, ...
Receptors for bone morphogenetic proteins (BMPs), members of the transforming growth factor-β (TGFβ) superfamily, are persistently expressed during cardiac development, yet mice lacking type II or...
MEKK1 is essential for cardiac hypertrophy and dysfunction induced by Gq
Minamino, Tetsuo, Yujiri, Toshiaki, Terada, Naohiro, Taffet, George E., Michael, Lloyd H., Johnson, Gary L., ...
Signaling via mitogen-activated protein kinases is implicated in heart failure induced by agonists for G protein-coupled receptors that act via the G protein Gαq. However, this assertion relies...
Telomere attrition and Chk2 activation in human heart failure
Oh, Hidemasa, Wang, Sam C., Prahash, Arun, Sano, Motoaki, Moravec, Christine S., Taffet, George E., ...
The “postmitotic” phenotype in adult cardiac muscle exhibits similarities to replicative senescence more generally and constitutes a barrier to effective restorative growth in heart disease....
Holtwick, Rita, Van Eickels, Martin, Skryabin, Boris V., Baba, Hideo A., Bubikat, Alexander, Begrow, Frank, ...
Cardiac hypertrophy is a common and often lethal complication of arterial hypertension. Atrial natriuretic peptide (ANP) has been postulated to exert local antihypertrophic effects in the heart....
A Wnt- and β-catenin-dependent pathway for mammalian cardiac myogenesis
Nakamura, Teruya, Sano, Motoaki, Songyang, Zhou, Schneider, Michael D.
Acquisition of a cardiac fate by embryonic mesodermal cells is a fundamental step in heart formation. Heart development in frogs and avians requires positive signals from adjacent endoderm, including...
Hamamori, Yasuo, Schneider, Michael D.
Histone acetylation, regulated by two antagonistic enzymes — histone acetyltransferases (HATs) and histone deacetylases (HDACs) — results in transcriptional changes and also plays a critical role...
Cardiac progenitor cells from adult myocardium: Homing, differentiation, and fusion after infarction
Oh, Hidemasa, Bradfute, Steven B., Gallardo, Teresa D., Nakamura, Teruya, Gaussin, Vinciane, Mishina, Yuji, ...
Potential repair by cell grafting or mobilizing endogenous cells holds particular attraction in heart disease, where the meager capacity for cardiomyocyte proliferation likely contributes to the...
Activation of cardiac Cdk9 represses PGC-1 and confers a predisposition to heart failure
Sano, Motoaki, Wang, Sam C, Shirai, Manabu, Scaglia, Fernando, Xie, Min, Sakai, Satoshi, ...
Hypertrophy allows the heart to adapt to workload but culminates in later pump failure; how it is achieved remains uncertain. Previously, we showed that hypertrophy is accompanied by activation of...
Unchain my heart: the scientific foundations of cardiac repair
Dimmeler, Stefanie, Zeiher, Andreas M., Schneider, Michael D.
In humans, the biological limitations to cardiac regenerative growth create both a clinical imperative — to offset cell death in acute ischemic injury and chronic heart failure — and a clinical...
Learning from failure: congestive heart failure in the postgenomic age
Benjamin, Ivor J., Schneider, Michael D.
The prognosis of heart failure is worse than that of most cancers, but new therapeutic interventions using stem and other cell-based therapies are succeeding in the fight against it, and old drugs,...
Atrioventricular cushion transformation is mediated by ALK2 in the developing mouse heart
Wang, Jikui, Sridurongrit, Somyoth, Dudas, Marek, Thomas, Penny, Nagy, Andre, Schneider, Michael D., ...
Developmental abnormalities in endocardial cushions frequently contribute to congenital heart malformations including septal and valvular defects. While compelling evidence has been presented to...
Garcia-Gras, Eduardo, Lombardi, Raffaella, Giocondo, Michael J., Willerson, James T., Schneider, Michael D., Khoury, Dirar S., ...
Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVC) is a genetic disease caused by mutations in desmosomal proteins. The phenotypic hallmark of ARVC is fibroadipocytic replacement of...
Oh, Hidemasa, Taffet, George E., Youker, Keith A., Entman, Mark L., Overbeek, Paul A., Michael, Lloyd H., ...
Cardiac muscle regeneration after injury is limited by “irreversible” cell cycle exit. Telomere shortening is one postulated basis for replicative senescence, via down-regulation of telomerase...
A Novel Rb- and p300-Binding Protein Inhibits Transactivation by MyoD
MacLellan, W. Robb, Xiao, G., Abdellatif, M., Schneider, Michael D.
The retinoblastoma protein (Rb) regulates both the cell cycle and tissue-specific transcription, by modulating the activity of factors that associate with its A-B and C pockets. In skeletal muscle,...
Abdellatif, Maha, Packer, Sharon E., Michael, Lloyd H., Zhang, Dou, Charng, Min Ji, Schneider, Michael D.
Despite extensive evidence implicating Ras in cardiac muscle hypertrophy, the mechanisms involved are unclear. We previously reported that Ras, through an effector-like function of Ras...
Gaussin, Vinciane, Van De Putte, Tom, Mishina, Yuji, Hanks, Mark C., Zwijsen, An, Huylebroeck, Danny, ...
Receptors for bone morphogenetic proteins (BMPs), members of the transforming growth factor-β (TGFβ) superfamily, are persistently expressed during cardiac development, yet mice lacking type II or...
MEKK1 is essential for cardiac hypertrophy and dysfunction induced by Gq
Minamino, Tetsuo, Yujiri, Toshiaki, Terada, Naohiro, Taffet, George E., Michael, Lloyd H., Johnson, Gary L., ...
Signaling via mitogen-activated protein kinases is implicated in heart failure induced by agonists for G protein-coupled receptors that act via the G protein Gαq. However, this assertion relies...
Telomere attrition and Chk2 activation in human heart failure
Oh, Hidemasa, Wang, Sam C., Prahash, Arun, Sano, Motoaki, Moravec, Christine S., Taffet, George E., ...
The “postmitotic” phenotype in adult cardiac muscle exhibits similarities to replicative senescence more generally and constitutes a barrier to effective restorative growth in heart disease....
Holtwick, Rita, Van Eickels, Martin, Skryabin, Boris V., Baba, Hideo A., Bubikat, Alexander, Begrow, Frank, ...
Cardiac hypertrophy is a common and often lethal complication of arterial hypertension. Atrial natriuretic peptide (ANP) has been postulated to exert local antihypertrophic effects in the heart....
A Wnt- and β-catenin-dependent pathway for mammalian cardiac myogenesis
Nakamura, Teruya, Sano, Motoaki, Songyang, Zhou, Schneider, Michael D.
Acquisition of a cardiac fate by embryonic mesodermal cells is a fundamental step in heart formation. Heart development in frogs and avians requires positive signals from adjacent endoderm, including...
Hamamori, Yasuo, Schneider, Michael D.
Histone acetylation, regulated by two antagonistic enzymes — histone acetyltransferases (HATs) and histone deacetylases (HDACs) — results in transcriptional changes and also plays a critical role...
Cardiac progenitor cells from adult myocardium: Homing, differentiation, and fusion after infarction
Oh, Hidemasa, Bradfute, Steven B., Gallardo, Teresa D., Nakamura, Teruya, Gaussin, Vinciane, Mishina, Yuji, ...
Potential repair by cell grafting or mobilizing endogenous cells holds particular attraction in heart disease, where the meager capacity for cardiomyocyte proliferation likely contributes to the...
Activation of cardiac Cdk9 represses PGC-1 and confers a predisposition to heart failure
Sano, Motoaki, Wang, Sam C, Shirai, Manabu, Scaglia, Fernando, Xie, Min, Sakai, Satoshi, ...
Hypertrophy allows the heart to adapt to workload but culminates in later pump failure; how it is achieved remains uncertain. Previously, we showed that hypertrophy is accompanied by activation of...
Unchain my heart: the scientific foundations of cardiac repair
Dimmeler, Stefanie, Zeiher, Andreas M., Schneider, Michael D.
In humans, the biological limitations to cardiac regenerative growth create both a clinical imperative — to offset cell death in acute ischemic injury and chronic heart failure — and a clinical...
Learning from failure: congestive heart failure in the postgenomic age
Benjamin, Ivor J., Schneider, Michael D.
The prognosis of heart failure is worse than that of most cancers, but new therapeutic interventions using stem and other cell-based therapies are succeeding in the fight against it, and old drugs,...
Garcia-Gras, Eduardo, Lombardi, Raffaella, Giocondo, Michael J., Willerson, James T., Schneider, Michael D., Khoury, Dirar S., ...
Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVC) is a genetic disease caused by mutations in desmosomal proteins. The phenotypic hallmark of ARVC is fibroadipocytic replacement of...
Essential role of TAK1 in thymocyte development and activation
Liu, Hong-Hsing, Xie, Min, Schneider, Michael D., Chen, Zhijian J.
The protein kinase TAK1 mediates the activation of NF-κB in response to stimulation by proinflammatory cytokines and microbial pathogens in the innate immunity pathways. However, the physiological...
Chang, Jiang, Xie, Min, Shah, Viraj R., Schneider, Michael D., Entman, Mark L., Wei, Lei, ...
Rho-associated coiled-coil protein kinase 1 (ROCK-1) is a direct cleavage substrate of activated caspase-3, which is associated with heart failure. In the course of human heart failure, we found...
Xie, Min, Zhang, Dou, Dyck, Jason R. B., Li, Yi, Zhang, Hui, Morishima, Masae, ...
TGF-β-activated kinase-1 (TAK1), also known as MAPKK kinase-7 (MAP3K7), is a candidate effector of multiple circuits in cardiac biology and disease. Here, we show that inhibition of TAK1 in mice by...
Haudek, Sandra B., Taffet, George E., Schneider, Michael D., Mann, Douglas L.
Transgenic mice with cardiac-restricted overexpression of secretable TNF (MHCsTNF) develop progressive LV wall thinning and dilation accompanied by an increase in cardiomyocyte apoptosis and a...
Sox17 is essential for the specification of cardiac mesoderm in embryonic stem cells
Liu, Yu, Asakura, Masanori, Inoue, Hironori, Nakamura, Teruya, Sano, Motoaki, Niu, Zhiyv, ...
Early steps for cardiac specification are problematic for the study of mammalian embryos, which has favored using pluripotent cells that recapitulate cardiac myogenesis. Furthermore, circuits...
Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure
Chen, Jian-Fu, Murchison, Elizabeth P., Tang, Ruhang, Callis, Thomas E., Tatsuguchi, Mariko, Deng, Zhongliang, ...
Cardiovascular disease is the leading cause of human morbidity and mortality. Dilated cardiomyopathy (DCM) is the most common form of cardiomyopathy associated with heart failure. Here, we report...
TAK1 is an essential regulator of BMP signalling in cartilage
Shim, Jae-Hyuck, Greenblatt, Matthew B, Xie, Min, Schneider, Michael D, Zou, Weiguo, Zhai, Bo, ...
TGFβ activated kinase 1 (TAK1), a member of the MAPKKK family, controls diverse functions ranging from innate and adaptive immune system activation to vascular development and apoptosis. To analyse...
Yu, Yang, Ge, Ningling, Xie, Min, Sun, Wenjing, Burlingame, Susan, Pass, Amy K., ...
TAK1 (transforming growth factor-β-activated kinase 1), a mitogen-activated protein kinase kinase kinase, is activated by various cytokines, including interleukin-1 (IL-1). However, the precise...